Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

COMPLETED Phase 3

Study of Efficacy and Safety of Two Secukinumab Dose Regimens in Subjects With Moderate to Severe Hidradenitis Suppurativa (HS)

NCT03713632 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study was to demonstrate superiority of secukinumab at Week 16, based on Hidradenitis Suppurativa Clinical Response (HiSCR) rates versus placebo, along with the maintenance of efficacy of secukinumab at Week 52 in subjects with moderate to severe HS. Moreover, this study assessed the safety and tolerability of secukinumab.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG Secukinumab

Study Locations (20)

Other

  • Novartis Investigative Site — Capital Federal
  • Novartis Investigative Site — Ghent
  • Novartis Investigative Site — Liège

California

  • Novartis Investigative Site — San Diego
  • Novartis Investigative Site — Whittier

Florida

  • Novartis Investigative Site — Coral Gables
  • Novartis Investigative Site — Tampa

Missouri

  • Novartis Investigative Site — St Louis
  • Novartis Investigative Site — St Louis

Texas

  • Novartis Investigative Site — Bellaire
  • Novartis Investigative Site — Pflugerville

Georgia

  • Novartis Investigative Site — Sandy Springs

Indiana

  • Novartis Investigative Site — Indianapolis

Massachusetts

  • Novartis Investigative Site — Boston

Trial Details

FieldValue
Enrollment Target 545 participants
Start Date 2019-02-25
Est. Completion 2022-07-19
Phase Phase 3

Sponsor

Novartis Pharmaceuticals

792 total trials

Interested in This Trial?

Always speak with your doctor before enrolling in a clinical trial.

Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT03713632

The ClinicalTrials.gov registry entry for NCT03713632 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 545 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Novartis Pharmaceuticals, which has 792 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Hidradenitis Suppurativa appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT03713632 reports 20 study locations spanning 14 distinct geographic areas — top geographies include Other, California, Florida. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT03713632 about?

NCT03713632 is a clinical study titled "Study of Efficacy and Safety of Two Secukinumab Dose Regimens in Subjects With Moderate to Severe Hidradenitis Suppurativa (HS)". The purpose of this study was to demonstrate superiority of secukinumab at Week 16, based on Hidradenitis Suppurativa Clinical Response (HiSCR) rates versus placebo, along with the maintenance of efficacy of secukinumab at Week 52 in subjects with moderate to severe HS. Moreover, this study assessed...

What is the current status of trial NCT03713632?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 545 participants. The study started on 2019-02-25. Estimated completion is 2022-07-19.

What conditions does trial NCT03713632 study?

This clinical trial studies the following conditions: Hidradenitis Suppurativa. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT03713632?

The interventions under investigation include: Placebo (DRUG), Secukinumab (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT03713632?

This trial is sponsored by Novartis Pharmaceuticals, which has 792 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT03713632 being conducted?

This trial has 20 study locations across California, Florida, Georgia, Indiana, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial