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A Study to Evaluate the Efficacy and Safety of AVTX-009 in Patients With Moderate to Severe Hidradenitis Suppurativa
NCT06603077 · View on ClinicalTrials.gov ↗
Study Summary
The main purpose of this study is to evaluate the efficacy and safety of AVTX-009 compared with placebo in patients with moderate to severe Hidradenitis Suppurativa (HS).
Conditions Studied
Interventions
- DRUG Placebo
- DRUG AVTX-009 Regimen 1
- DRUG AVTX-009 Regimen 2
Study Locations (20)
Florida
- Clinical Site 1029 — Boca Raton
- Clinical Site 1002 — Coral Gables
- Clinical Site 1015 — Maitland
- Clinical Site 1027 — North Miami Beach
- Clinical Site 1013 — Tampa
California
- Clinical Site 1032 — Northridge
- Clinical Site 1019 — Pomona
- Clinical Site 1009 — Sacramento
- Clinical Site 1034 — Santa Monica
Arizona
- Clinical Site 1022 — Scottsdale
- Clinical Site 1037 — Scottsdale
- Clinical Site 1026 — Tucson
Kentucky
- Clinical Site 1031 — Bowling Green
- Clinical Site 1024 — Murray
Massachusetts
- Clinical Site 1042 — Boston
- Clinical Site 1001 — Boston
District of Columbia
- Clinical Site 1011 — Washington D.C.
Georgia
- Clinical Site 1008 — Savannah
Illinois
- Clinical Site 1014 — Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 250 participants |
| Start Date | 2024-09-16 |
| Est. Completion | 2026-04 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06603077
The ClinicalTrials.gov registry entry for NCT06603077 describes a study currently listed as active not recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 250 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Avalo Therapeutics, which has 3 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Hidradenitis Suppurativa appearing as the primary indexed condition, and to 3 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06603077 reports 20 study locations spanning 9 distinct geographic areas — top geographies include Florida, California, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06603077 about?
NCT06603077 is a clinical study titled "A Study to Evaluate the Efficacy and Safety of AVTX-009 in Patients With Moderate to Severe Hidradenitis Suppurativa". The main purpose of this study is to evaluate the efficacy and safety of AVTX-009 compared with placebo in patients with moderate to severe Hidradenitis Suppurativa (HS).
What is the current status of trial NCT06603077?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 250 participants. The study started on 2024-09-16. Estimated completion is 2026-04.
What conditions does trial NCT06603077 study?
This clinical trial studies the following conditions: Hidradenitis Suppurativa. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06603077?
The interventions under investigation include: Placebo (DRUG), AVTX-009 Regimen 1 (DRUG), AVTX-009 Regimen 2 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06603077?
This trial is sponsored by Avalo Therapeutics, which has 3 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06603077 being conducted?
This trial has 20 study locations across Arizona, California, District of Columbia, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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