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NCT06958211 · ClinicalTrials.gov registry record · Phase 3
Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa (TRuE-HS2)
A Phase 3 study of Hidradenitis Suppurativa, sponsored by Incyte Corporation.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 550
- Enrollment target
- 20
- Study locations
NCT06958211: Recruiting Phase 3 study of Hidradenitis Suppurativa, sponsored by Incyte Corporation.
NCT06958211 is a Phase 3 study of Hidradenitis Suppurativa that is actively recruiting participants, run by Incyte Corporation. The registered enrollment target is 550 participants, roughly in line with the 588-participant average among 52 other Hidradenitis Suppurativa trials with a reported enrollment target. The trial reports 20 study locations across 6 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06958211, a Phase 3 study of Hidradenitis Suppurativa, is actively recruiting participants, sponsored by Incyte Corporation.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 550 participants
- Enrollment target
- 20
- Study locations
Study Summary
The purpose of this study is to evaluate the efficacy and safety of ruxolitinib cream in participants with hidradenitis suppurativa.
Primary Outcome
HiSCR75 is defined as at least a 75% reduction from baseline in the total abscess and/or inflammatory nodule (AN) count with no increase from baseline in abscess or draining tunnel count.
Conditions Studied
Interventions
- DRUG Ruxolitinib Cream
- DRUG Vehicle Cream
Study Locations (20)
California
- Investigative Site US262 - Encino
- Investigative Site US222 - Fountain Valley
- Investigative Site US211 - Los Angeles
- Investigative Site US237 - Los Angeles
- Investigative Site US234 - Northridge
- Investigative Site US250 - Santa Ana
Florida
- Investigative Site US208 - Boca Raton
- Investigative Site US203 - Hialeah
- Investigative Site US258 - Jacksonville
- Investigative Site US206 - Maitland
- Investigative Site US223 - Miami
Arizona
- Investigative Site US215 - Phoenix
- Investigative Site US261 - Phoenix
- Investigative Site US221 - Scottsdale
- Investigative Site US240 - Tucson
Alabama
- Investigative Site US257 - Birmingham
- Investigative Site US218 - Birmingham
- Investigative Site US239 - Montgomery
Colorado
- Investigative Site US244 - Castle Rock
Connecticut
- Investigative Site US252 - Cromwell
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 550 participants |
| Start Date | 2025-06-12 |
| Est. Completion | 2027-07-11 |
| Phase | Phase 3 |
What NCT06958211 shows while recruiting
NCT06958211 is an interventional study that assigns participants to a tested intervention. The registered 550 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 588-participant average among 52 other Hidradenitis Suppurativa trials with a reported enrollment target.
The record links to 1 condition, with Hidradenitis Suppurativa appearing as the primary indexed condition, and to 2 interventions - of which Ruxolitinib Cream is the first listed.
NCT06958211 names 20 study sites across 6 states, led by California, Florida, Arizona.
Frequently Asked Questions
What is clinical trial NCT06958211 about?
NCT06958211 is a clinical study titled "Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa (TRuE-HS2)". The purpose of this study is to evaluate the efficacy and safety of ruxolitinib cream in participants with hidradenitis suppurativa.
What is the current status of trial NCT06958211?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 550 participants. The study started on 2025-06-12. Estimated completion is 2027-07-11.
What conditions does trial NCT06958211 study?
This clinical trial studies the following conditions: Hidradenitis Suppurativa.
What interventions are being tested in trial NCT06958211?
The interventions under investigation include: Ruxolitinib Cream (DRUG), Vehicle Cream (DRUG).
Who is sponsoring clinical trial NCT06958211?
This trial is sponsored by Incyte Corporation, which has 239 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06958211 being conducted?
This trial has 20 study locations across Alabama, Arizona, California, Colorado, Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT06958211's enrollment target sits among peer trials
550 11th of 52 higher than 41 of 52 other Hidradenitis Suppurativa trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hidradenitis Suppurativa trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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