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A Study of Eltrekibart (LY3041658) in Adult Participants With Moderate to Severe Hidradenitis Suppurativa
NCT06046729 · View on ClinicalTrials.gov ↗
Study Summary
This study aims to find the appropriately safe and effective dose and dosing frequency for eltrekibart in adults with moderate-to-severe hidradenitis suppurativa (HS) for further clinical development. The study will last approximately 62 weeks and may include up to 31 visits.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Eltrekibart
Study Locations (20)
Florida
- Direct Helpers Research Center — Hialeah
- University of Miami — Miami
- Skin Research of South Florida — Miami
- ForCare Clinical Research — Tampa
- Alliance Clinical Research of Tampa — Tampa
- Olympian Clinical Research — Tampa
California
- First OC Dermatology Research Inc — Fountain Valley
- Center For Dermatology Clinical Research, Inc. — Fremont
- Dermatology Research Associates — Los Angeles
- Dermatology Institute and Skin Care Center — Santa Monica
Arizona
- Medical Dermatology Specialists — Phoenix
- Saguaro Dermatology Associates, LLC - Probity - PPDS — Phoenix
Arkansas
- Arkansas Research Trials, LLC — North Little Rock
- Northwest Arkansas Clinical Trials Center — Rogers
Kentucky
- Equity Medical - Bowling Green — Bowling Green
- Derm Research LLC — Louisville
Connecticut
- University of Connecticut — Farmington
Georgia
- Advanced Medical Research, PC — Sandy Springs
Illinois
- NorthShore Medical Group Dermatology - Skokie — Skokie
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 352 participants |
| Start Date | 2023-10-23 |
| Est. Completion | 2026-08 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06046729
The ClinicalTrials.gov registry entry for NCT06046729 describes a study currently listed as active not recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 352 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Eli Lilly and Company, which has 704 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Hidradenitis Suppurativa appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06046729 reports 20 study locations spanning 9 distinct geographic areas — top geographies include Florida, California, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06046729 about?
NCT06046729 is a clinical study titled "A Study of Eltrekibart (LY3041658) in Adult Participants With Moderate to Severe Hidradenitis Suppurativa". This study aims to find the appropriately safe and effective dose and dosing frequency for eltrekibart in adults with moderate-to-severe hidradenitis suppurativa (HS) for further clinical development. The study will last approximately 62 weeks and may include up to 31 visits.
What is the current status of trial NCT06046729?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 352 participants. The study started on 2023-10-23. Estimated completion is 2026-08.
What conditions does trial NCT06046729 study?
This clinical trial studies the following conditions: Hidradenitis Suppurativa. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06046729?
The interventions under investigation include: Placebo (DRUG), Eltrekibart (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06046729?
This trial is sponsored by Eli Lilly and Company, which has 704 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06046729 being conducted?
This trial has 20 study locations across Arizona, Arkansas, California, Connecticut, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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