Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Mental Health Issue clinical trials
Every US clinical trial registered for Mental Health Issue — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
53 US clinical trials · 39 currently recruiting
The research picture
Mental Health Issue has 53 registered US clinical trials, 39 of them open to new participants right now — about 74% of the total.
- 39
- recruiting participants now
- 74%
- of trials open to enrollment
- 1
- in Phase 3–4 (later-stage)
- 6
- top sponsor: Yale University
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Building Resilience at Schools: Emotional and Biological Assessment and Treatment of Traumatic Stress
Stanford University
NCT05701111
Centralized Virtual SBIRT for Pediatric Primary Care
Kaiser Permanente
NCT06486688
Implementation Supports for Improving Identification and Delivery of School-based Mental Health Supports for Middle Schools Students
University of Virginia
NCT06047041
Unified Protocol: Community Connections
University of Miami
NCT06038721
Evaluating Personalized Therapeutics Clinic (PTC) on Drug-Drug Interactions and Drug-Gene Interactions
University of Chicago
NCT05166694
Culturally Responsive Community Driven Substance Use Recovery for Black and Latinx Population
Yale University
NCT05260047
AIMS Medical Outcomes Study
Advanced Integrative Medical Science Institute
NCT04512755
Affirmative Psychotherapy for Sexual Minority Women's Mental and Behavioral Health
Yale University
NCT05509166
TEAMS R34 #1 After-Action Reviews in Child Welfare Services
University of California, San Diego
NCT05629013
Teachers Leading the Front Lines - North Carolina (Tealeaf-NC)
University of North Carolina, Chapel Hill
NCT06587230
Gii'Igoshimong: Sitting With Your First Family
Johns Hopkins Bloomberg School of Public Health
NCT07075081
Striving Towards EmPowerment and Medication Adherence R01
University of Miami
NCT06463886
Recovery Finance: Financial Health and Mental Health After Incarceration
Yale University
NCT06914856
Investigating Dyadic Expectations About ARF Survivorship (IDEAS)
Johns Hopkins University
NCT06401239
Clinical Validation of Samsung Smartwatch
Massachusetts General Hospital
NCT05767593
Family Spirit Strengths
Johns Hopkins Bloomberg School of Public Health
NCT05836090
Building a Renewed ImaGe After Head & Neck Cancer Treatment (BRIGHT) Multi-Site RCT
Medical University of South Carolina
NCT05442957
Stress Phenotypes and Preterm Birth
Columbia University
NCT05229666
Viome Precision Nutritional Programs to Improve Clinical Outcomes for Mental Health Disorders
Viome
NCT06502717
Proximal Risk for Suicide in Adolescents
Oregon Health and Science University
NCT06400810
Affirmative Family and Individual Psychotherapy for Sexual and Gender Minority Adults and Their Nonaccepting Parents
Yale University
NCT05766592
Adolescent Screening and Personalized Intervention Resource for Enhancement of Behavioral Health and Substance Use
Oregon Research Institute
NCT06306287
PrEP Intervention in Prince George's County, Maryland
George Mason University
NCT06141408
Evaluating Digital Micro-Interventions to Reduce Distress and Increase Wellbeing in Breast Cancer Survivors
University of Virginia
NCT07160439
Just-in-Time Training for Youth Mentors
University of Minnesota
NCT07129070
Improving the Mental Health of Home Health Aides
Weill Medical College of Cornell University
NCT06071221
Music Mindfulness Study 2a.
Yale University
NCT06505226
Weyera Mental Health Pilot Intervention
Emory University
NCT06960187
LinkPositively+ A Mobile Health App Delivered Intervention to Improve HIV Care Outcomes Among Black Women Affected by Mental Health and Violence
Guiding Right
NCT06458660
Improving Mental Health for Care Partners of Persons With AD/ADRD
Texas Tech University
NCT05334992
Anterior Cruciate Ligament Recovery With Virtual Psychological Intervention
Henry Ford Health System
NCT05965310
Single Session Narrative Therapy Study
University of Washington
NCT06479980
Telehealth to Reduce Mental Health in Family Caregivers
Texas Tech University
NCT05696704
Telehealth to Improve Quality of Life in Persons Living in Rural Texas
Texas Tech University
NCT07119710
Implementation Supports to Reduce Burnout in Therapists Delivering Child Trauma EBPs
San Diego State University
NCT04712461
A rTMS and Virtual Reality Based Cognitive Rehabilitation Program for MCI
Central Arkansas Veterans Healthcare System
NCT06024473
Feasibility of a Prenatal Yoga Mobile App in African American Pregnant Women
San Diego State University
NCT06353113
Evaluating the Impact of Social Music
Yale University
NCT06513910
Evaluating a New Mental Health Group for Asians and Asian Americans
Stanford University
NCT06185959
Improving Maternal Mental Health & SUD Screening and Treatment
Medical University of South Carolina
NCT05764213
Pathways to Improved Adolescent Mental Health in Conflict Affected Families
Johns Hopkins University
NCT05763719
Intervention to Address Disparate Mental Health Consequences of COVID-19 Pandemic on Latinx and African Newcomers
University of New Mexi
NCT05092542
Assisted Identification and Navigation of Early Mental Health Symptoms in Children
Kaiser Permanente
NCT05064293
Intervention for Virologic Suppression in Youth
University of California, San Francis
NCT05877729
Tell Me More ("Dime Mas")
University of Miami
NCT06063083
A Music and Visual Arts Digital Intervention in Teenagers to Promote Healthy Engagement With Social Media.
New York University
NCT06402253
Sweet Scents to Sweet Dreams
Duquesne University
NCT06247696
SSIs for Mental Health and Loneliness
University of California, Irvine
NCT05687162
Optimizing Implementation Coaching to Support Successful EBP Delivery
University of Washington
NCT05799794
Mental Health, Gender-Based Violence, and Stunting in Tanzania
Colorado State University
NCT06065293
The Development and Evaluation of a Single Session Intervention for Parent Distress Tolerance
University of Miami
NCT05955898
The Acceptability and Feasibility of an ED-based, Peer-delivered, Suicide Safety Planning Intervention
University of Arkansas
NCT04068142
Culturally Tailored Mindfulness-Positive Psychological Intervention Using Virtual Reality
University of Illinois at Urbana-Champaign
NCT06019416
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 1 |
| Phase 3 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Mental Health Issue Trial Landscape
ClinicalTrials.gov lists 53 US studies indexed under Mental Health Issue, and 39 of those are currently open to recruitment — roughly 74% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Mental Health Issue shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 1 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Mental Health Issue is led by Yale University with 6 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 53 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Mental Health Issue?
PlainTrial tracks 53 US clinical trials for Mental Health Issue, of which 39 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Mental Health Issue?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.