Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Mental Health Issue: full-pipeline trial registry
39 of 53 indexed Mental Health Issue trials are currently recruiting.
Corpus placement: #265 of 28,707 conditions by registered trial count.
53 US clinical trials · 39 currently recruiting · #265 of 28,707 conditions by registered trial count
Mental Health Issue: 53 US clinical trials tracked, 39 recruiting.
Mental Health Issue is the subject of 53 registered US clinical trials on ClinicalTrials.gov, 39 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Yale University, running 6 of these trials.
Enrollment posture brief
Registry condition mental-health-issue
OPEN 39 | RECR 74% | LATE 1 | EARLY 1 | RANK #265 | SPON 6
Volume-matched condition peers
Nearest open-share peer: Metabolic Disease (74% recruiting · 34 trials)
Mental Health Issue lists 39 open slots (74% of 53 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Mental Health Issue on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Mental Health Issue is recruiting above its size-band peers.
39 of 53 indexed trials (73.6%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Mental Health Issue trials is spread across many organizations.
Yale University accounts for 6 of 53 trials (11.3%). 35 distinct sponsors appear on at least one study for this condition label.
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Typical Mental Health Issue enrolment sits around 150 participants.
Median target enrolment is 150 among the 53 trials that report a genuine target (sentinel values excluded). 19 of those (35.8%) plan for fewer than 100 participants.
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Mental Health Issue research is mostly interventional.
47 interventional and 6 observational studies make up this index (88.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
53 total, page 1 of 2
Building Resilience at Schools: Emotional and Biological Assessment and Treatment of Traumatic Stress
Stanford University
NCT05701111
Centralized Virtual SBIRT for Pediatric Primary Care
Kaiser Permanente
NCT06486688
Implementation Supports for Improving Identification and Delivery of School-based Mental Health Supports for Middle Schools Students
University of Virginia
NCT06047041
Unified Protocol: Community Connections
University of Miami
NCT06038721
Evaluating Personalized Therapeutics Clinic (PTC) on Drug-Drug Interactions and Drug-Gene Interactions
University of Chicago
NCT05166694
Culturally Responsive Community Driven Substance Use Recovery for Black and Latinx Population
Yale University
NCT05260047
AIMS Medical Outcomes Study
Advanced Integrative Medical Science Institute
NCT04512755
Affirmative Psychotherapy for Sexual Minority Women's Mental and Behavioral Health
Yale University
NCT05509166
TEAMS R34 #1 After-Action Reviews in Child Welfare Services
University of California, San Diego
NCT05629013
Teachers Leading the Front Lines - North Carolina (Tealeaf-NC)
University of North Carolina, Chapel Hill
NCT06587230
Gii'Igoshimong: Sitting With Your First Family
Johns Hopkins Bloomberg School of Public Health
NCT07075081
Striving Towards EmPowerment and Medication Adherence R01
University of Miami
NCT06463886
Recovery Finance: Financial Health and Mental Health After Incarceration
Yale University
NCT06914856
Investigating Dyadic Expectations About ARF Survivorship (IDEAS)
Johns Hopkins University
NCT06401239
Clinical Validation of Samsung Smartwatch
Massachusetts General Hospital
NCT05767593
Family Spirit Strengths
Johns Hopkins Bloomberg School of Public Health
NCT05836090
Building a Renewed ImaGe After Head & Neck Cancer Treatment (BRIGHT) Multi-Site RCT
Medical University of South Carolina
NCT05442957
Stress Phenotypes and Preterm Birth
Columbia University
NCT05229666
Viome Precision Nutritional Programs to Improve Clinical Outcomes for Mental Health Disorders
Viome
NCT06502717
Proximal Risk for Suicide in Adolescents
Oregon Health and Science University
NCT06400810
Affirmative Family and Individual Psychotherapy for Sexual and Gender Minority Adults and Their Nonaccepting Parents
Yale University
NCT05766592
Adolescent Screening and Personalized Intervention Resource for Enhancement of Behavioral Health and Substance Use
Oregon Research Institute
NCT06306287
PrEP Intervention in Prince George's County, Maryland
George Mason University
NCT06141408
Evaluating Digital Micro-Interventions to Reduce Distress and Increase Wellbeing in Breast Cancer Survivors
University of Virginia
NCT07160439
Just-in-Time Training for Youth Mentors
University of Minnesota
NCT07129070
Improving the Mental Health of Home Health Aides
Weill Medical College of Cornell University
NCT06071221
Music Mindfulness Study 2a.
Yale University
NCT06505226
Weyera Mental Health Pilot Intervention
Emory University
NCT06960187
LinkPositively+ A Mobile Health App Delivered Intervention to Improve HIV Care Outcomes Among Black Women Affected by Mental Health and Violence
Guiding Right
NCT06458660
Improving Mental Health for Care Partners of Persons With AD/ADRD
Texas Tech University
NCT05334992
Anterior Cruciate Ligament Recovery With Virtual Psychological Intervention
Henry Ford Health System
NCT05965310
Single Session Narrative Therapy Study
University of Washington
NCT06479980
Telehealth to Reduce Mental Health in Family Caregivers
Texas Tech University
NCT05696704
Telehealth to Improve Quality of Life in Persons Living in Rural Texas
Texas Tech University
NCT07119710
Implementation Supports to Reduce Burnout in Therapists Delivering Child Trauma EBPs
San Diego State University
NCT04712461
A rTMS and Virtual Reality Based Cognitive Rehabilitation Program for MCI
Central Arkansas Veterans Healthcare System
NCT06024473
Feasibility of a Prenatal Yoga Mobile App in African American Pregnant Women
San Diego State University
NCT06353113
Evaluating the Impact of Social Music
Yale University
NCT06513910
Evaluating a New Mental Health Group for Asians and Asian Americans
Stanford University
NCT06185959
Improving Maternal Mental Health & SUD Screening and Treatment
Medical University of South Carolina
NCT05764213
Pathways to Improved Adolescent Mental Health in Conflict Affected Families
Johns Hopkins University
NCT05763719
Intervention to Address Disparate Mental Health Consequences of COVID-19 Pandemic on Latinx and African Newcomers
University of New Mexi
NCT05092542
Assisted Identification and Navigation of Early Mental Health Symptoms in Children
Kaiser Permanente
NCT05064293
Intervention for Virologic Suppression in Youth
University of California, San Francisco
NCT05877729
Tell Me More ("Dime Mas")
University of Miami
NCT06063083
A Music and Visual Arts Digital Intervention in Teenagers to Promote Healthy Engagement With Social Media.
New York University
NCT06402253
Sweet Scents to Sweet Dreams
Duquesne University
NCT06247696
SSIs for Mental Health and Loneliness
University of California, Irvine
NCT05687162
Optimizing Implementation Coaching to Support Successful EBP Delivery
University of Washington
NCT05799794
Mental Health, Gender-Based Violence, and Stunting in Tanzania
Colorado State University
NCT06065293
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 1 |
| Phase 3 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Mental Health Issue records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Mental Health Issue trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Mental Health Issue page
53 registered trials, 39 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 39 Mental Health Issue trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Yale University sponsors the most Mental Health Issue trials on record, review their full trial history before evaluating a specific study. See Yale University's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Mental Health Issue condition card totals 53 registered trials; most-linked intervention Standard of Care; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.