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A Study of the Efficacy and Safety of Brensocatib in Adults With Moderate to Severe Hidradenitis Suppurativa (HS)
NCT06685835 · View on ClinicalTrials.gov ↗
Study Summary
The primary purpose of the study is to evaluate the effect of brensocatib compared with placebo.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Brensocatib
Study Locations (20)
Florida
- USA026 — Coral Gables
- USA027 — Hollywood
- USA021 — Margate
- USA018 — Miami
- USA025 — Ocala
- USA004 — Tampa
- USA010 — Weston
Georgia
- USA028 — Atlanta
- USA011 — Sandy Springs
Michigan
- USA012 — Detroit
- USA024 — Fort Gratiot
Arizona
- USA001 — Phoenix
California
- USA007 — Sacramento
Indiana
- USA003 — Plainfield
Louisiana
- USA002 — Baton Rouge
Massachusetts
- USA017 — Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 214 participants |
| Start Date | 2024-12-16 |
| Est. Completion | 2026-11-17 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06685835
The ClinicalTrials.gov registry entry for NCT06685835 describes a study currently listed as active not recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 214 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Insmed Incorporated, which has 11 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Hidradenitis Suppurativa appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06685835 reports 20 study locations spanning 12 distinct geographic areas — top geographies include Florida, Georgia, Michigan. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06685835 about?
NCT06685835 is a clinical study titled "A Study of the Efficacy and Safety of Brensocatib in Adults With Moderate to Severe Hidradenitis Suppurativa (HS)". The primary purpose of the study is to evaluate the effect of brensocatib compared with placebo.
What is the current status of trial NCT06685835?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 214 participants. The study started on 2024-12-16. Estimated completion is 2026-11-17.
What conditions does trial NCT06685835 study?
This clinical trial studies the following conditions: Hidradenitis Suppurativa. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06685835?
The interventions under investigation include: Placebo (DRUG), Brensocatib (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06685835?
This trial is sponsored by Insmed Incorporated, which has 11 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06685835 being conducted?
This trial has 20 study locations across Arizona, California, Florida, Georgia, Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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