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NCT07244263 · ClinicalTrials.gov registry record · Phase 2

A Study of Zasocitinib in Adults With Hidradenitis Suppurativa

A Phase 2 study of Hidradenitis Suppurativa, sponsored by Takeda.

Recruiting
Registry status
Phase 2
Development phase
90
Enrollment target
20
Study locations

NCT07244263 is a Phase 2 study of Hidradenitis Suppurativa that is actively recruiting participants, run by Takeda. The registered enrollment target is 90 participants, below the 596-participant average among 52 other Hidradenitis Suppurativa trials with a reported enrollment target (85% lower). The trial reports 20 study locations across 13 states.

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The verdict

NCT07244263, a Phase 2 study of Hidradenitis Suppurativa, is actively recruiting participants, sponsored by Takeda.

RECRUITING
Registry status
Phase 2
Development phase
90 participants
Enrollment target
20
Study locations

Study Summary

Hidradenitis Suppurativa (HS) is a skin condition that causes deep, painful bumps on the skin. These bumps usually appear in an area where the skin rubs together. They start as small bumps but may become swollen and red over time. If they fill with pus, these lumps are called abscesses; these can also burst. Over time, the area can get scars and tunnels on or under the skin. Recent studies suggest that the condition may start when hair follicles become damaged and blocked. This impacts the skin and may activate the body's germ-fighting (immune) system. This allows bacteria to grow on the skin which worsens the condition and can cause abscesses. The main aims of this study are to learn how safe zasocitinib is, how well it works and how well adults with HS tolerate it compared with a placebo. The participants will receive the study treatment (either zasocitinib or placebo) for up to 4 months (16 weeks). The placebo looks like the zasocitinib capsule but does not have any medicine in it. After the first 4 months, all participants (also those who initially received placebo) will then receive zasocitinib for up to 8 months (36 weeks). During the study, participants will visit their study clinic 12 times.

Conditions Studied

Interventions

  • OTHER Placebo
  • DRUG Zasocitinib (Dose A)

Study Locations (20)

Victoria

  • Skin Health Institute Inc. - Carlton
  • Sinclair Dermatology - Melbourne
  • Alfred Hospital - Melbourne

Florida

  • Direct Helpers Research Center - Hialeah
  • Advanced Clinical Research Institute - Tampa

Michigan

  • Wayne State University - Detroit
  • Hamzavi Dermatology - Fort Gratiot

New York

  • Northwell Health Physician Partners - Lake Success
  • Mount Sinai Doctors - New York

Texas

  • Arlington Research Center, Inc. - Arlington
  • Texas Dermatology Research Center - Dallas

New South Wales

  • Skin & Cancer Foundation - The Skin Hospital - Darlinghurst
  • Westmead Hospital - Westmead

Arizona

  • Mayo Clinic - Scottsdale

Arkansas

  • Johnson Dermatology - Fort Smith

Trial Details

FieldValue
Enrollment Target 90 participants
Start Date 2026-01-26
Est. Completion 2028-02-22
Phase Phase 2

Sponsor

Takeda

408 total trials

What the Registry Record Tells You About NCT07244263

The ClinicalTrials.gov registry entry for NCT07244263 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 90 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 596-participant average among 52 other Hidradenitis Suppurativa trials with a reported enrollment target (85% lower). The listed sponsor is Takeda, which has 408 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Hidradenitis Suppurativa appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT07244263 reports 20 study locations spanning 13 distinct geographic areas - top geographies include Victoria, Florida, Michigan.

Frequently Asked Questions

What is clinical trial NCT07244263 about?

NCT07244263 is a clinical study titled "A Study of Zasocitinib in Adults With Hidradenitis Suppurativa". Hidradenitis Suppurativa (HS) is a skin condition that causes deep, painful bumps on the skin. These bumps usually appear in an area where the skin rubs together. They start as small bumps but may become swollen and red over time. If they fill with pus, these lumps are called abscesses; these can al...

What is the current status of trial NCT07244263?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 90 participants. The study started on 2026-01-26. Estimated completion is 2028-02-22.

What conditions does trial NCT07244263 study?

This clinical trial studies the following conditions: Hidradenitis Suppurativa.

What interventions are being tested in trial NCT07244263?

The interventions under investigation include: Placebo (OTHER), Zasocitinib (Dose A) (DRUG).

Who is sponsoring clinical trial NCT07244263?

This trial is sponsored by Takeda, which has 408 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07244263 being conducted?

This trial has 20 study locations across Arizona, Arkansas, California, Florida, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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