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ClinicalTrials.gov 13 recruiting now early-phase tilt

Medication Adherence: early-phase trial registry

13 of 53 indexed Medication Adherence trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #265 of 28,707 conditions by registered trial count.

53 US clinical trials · 13 currently recruiting · #265 of 28,707 conditions by registered trial count

Medication Adherence: 53 US clinical trials tracked, 13 recruiting.

Medication Adherence is the subject of 53 registered US clinical trials on ClinicalTrials.gov, 13 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is Johns Hopkins University, running 3 of these trials.

Enrollment posture brief

Registry condition medication-adherence

OPEN 13 | RECR 25% | LATE 1 | EARLY 8 | RANK #265 | SPON 3

Nearest open-share peer: Burns (24% recruiting · 37 trials)

Mental Health Issue73.6%Metastatic Solid Tumor69.8%Hidradenitis Suppurativa54.7%Depressive Disorder, Major26.4%Medication Adherence (this)25%
Open-enrollment share among volume-matched conditions near Medication Adherence

Medication Adherence lists 13 open slots (25% of 53 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Medication Adherence on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Medication Adherence is recruiting below its size-band peers.

    13 of 53 indexed trials (24.5%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Medication Adherence trials is spread across many organizations.

    Johns Hopkins University accounts for 3 of 53 trials (5.7%). 45 distinct sponsors appear on at least one study for this condition label.

  3. Typical Medication Adherence enrolment sits around 150 participants.

    Median target enrolment is 150 among the 53 trials that report a genuine target (sentinel values excluded). 21 of those (39.6%) plan for fewer than 100 participants.

  4. Medication Adherence research is mostly interventional.

    48 interventional and 5 observational studies make up this index (90.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 15Phase 23Phase 41

Open and recent trials

53 total, page 1 of 2

RECRUITING NA 600 participants

Mobile Cued Adherence Therapy (mCAT) for Blood Pressure Medication

Chad Stecher@asu.edu

NCT06876233

RECRUITING NA 584 participants

Refinement and Testing of Recruitment Methodology for Behavioral Medication Adherence Interventions Using Behavioral Science-based Approaches

Brigham and Women's Hospital

NCT06569290

RECRUITING NA 402 participants

Medication Adherence Program

Tulane University

NCT05183763

RECRUITING NA 360 participants

Technology Enabled Strategies to Promote Treatment Adherence in Liver Transplant

University of Pennsylvania

NCT05260268

RECRUITING NA 328 participants

Improving Medication Adherence Using Family-focused and Literacy-sensitive Strategies

Jia-Rong Wu

NCT05548413

RECRUITING NA 300 participants

Women Focused Encounters for Resilience Independence Strength and Eudaimonia

University of California, San Diego

NCT06216600

RECRUITING NA 217 participants

My Interprofessional Care Team for Adherence and Research Engagement Disparities

University of Arizona

NCT05470439

RECRUITING NA 200 participants

A Mobile Gaming App to Improve Adherence to PrEP

Rhode Island Hospital

NCT05762705

RECRUITING NA 190 participants

MITIGAAT: Multifaceted Intervention to Improve Graft Outcome Disparities in African American Kidney Transplants

Medical University of South Carolina

NCT06023615

RECRUITING NA 150 participants

The Youth Opioid Recovery Support (YORS) Intervention

Potomac Health Foundations

NCT04173416

RECRUITING Phase 2 110 participants

An Integrated Intervention Using a Pill Ingestible Sensor System

University of California, Los Angeles

NCT06480578

RECRUITING NA 108 participants

Reducing Psychological Barriers to PrEP Persistence Among Pregnant and Postpartum Women in Cape Town, South Africa

Boston University Charles River Campus

NCT05624931

RECRUITING NA 100 participants

1MoreStep: An Intervention to Increase HIV Care Engagement and Reduce Intimate Partner Violence Among Black Women Living With HIV

Johns Hopkins University

NCT05608421

ACTIVE NOT RECRUITING NA 239 participants

PrEP Affect Regulation Treatment Innovation

Florida International University

NCT04899024

ACTIVE NOT RECRUITING 150 participants

Medication Adherence in Patients With Sarcoidosis

Johns Hopkins University

NCT05438095

ACTIVE NOT RECRUITING NA 150 participants

Assessment of Medherent Medication Management Device and Adherence Platform

Terrapin Pharmacy

NCT03775044

ACTIVE NOT RECRUITING NA 75 participants

Implementation Strategies for Monitoring Adherence in Real Time

Abramson Cancer Center at Penn Medicine

NCT04347161

ACTIVE NOT RECRUITING NA 70 participants

REACH-Es: Adapting a Digital Health Tool to Improve Diabetes Medication Adherence Among Latino Adults

Massachusetts General Hospital

NCT06000813

ACTIVE NOT RECRUITING Phase 2 70 participants

Preventing Medication Mismanagement in People Living with Dementia Through Automated Medication Dispensing with Facial Recognition and Video Observation

HiDO Technologies

NCT06691256

ACTIVE NOT RECRUITING NA 40 participants

MHealth Incentivized Adherence Plus Patient Navigation

University of Washington

NCT06027814

COMPLETED NA 65,177 participants

Social Norms, Messengers, and Processing Fluency to Increase Hypertension Medication Adherence

Brigham and Women's Hospital

NCT06066541

COMPLETED NA 9,501 participants

Personalized Patient Data and Behavioral Nudges to Improve Adherence to Chronic Cardiovascular Medications

University of Colorado, Denver

NCT03973931

COMPLETED NA 1,726 participants

Addressing Antihypertensive Medication Adherence Through EHR-enabled Teamlets in Primary Care

NYU Langone Health

NCT05349422

COMPLETED NA 755 participants

Patient-Centered Models of HCV Care for People Who Inject Drugs

Prisma Health-Upstate

NCT02824640

COMPLETED NA 712 participants

Evaluation of an Interactive Opioid Risk Education Program (STOMP) for Parents

University of Michigan

NCT03287622

COMPLETED Phase 1 600 participants

Nurse Delivered Cell Phone Adherence Intervention (Pick It UP)

University of Connecticut

NCT01359280

COMPLETED NA 473 participants

Improving Medication Adherence in the Alabama Black Belt

Weill Medical College of Cornell University

NCT02274844

COMPLETED NA 371 participants

Medications for Chronic HIV: Education and Collaboration

Boston University

NCT01038076

COMPLETED 292 participants

Identifying Factors Underlying the Discontinuation of Triptans

Mayo Clinic

NCT00890357

COMPLETED 276 participants

Antibiotic Adherence Practices in Dermatologic Surgery

University of Pennsylvania

NCT04117724

COMPLETED NA 200 participants

Federal Study of Adherence to Medications in the Elderly (FAME)

Walter Reed Army Medical Center

NCT00393419

COMPLETED Phase 2 176 participants

Study to Test the Efficacy of Online Education to Increase Safe Use of Opioid Medication.

Inflexxion

NCT01770314

COMPLETED NA 174 participants

Improving HIV and Alcohol-Related Outcomes Among HIV+ Persons in Clinic Settings

Hunter College of City University of New York

NCT02390908

COMPLETED NA 170 participants

Intervention to Improve Adherence in Teen Kidney Transplant

McGill University Health Centre/Research Institute of the McGill University Health Centre

NCT01356277

COMPLETED NA 107 participants

The eyeGuide: Improving Glaucoma Self-management With a Personalized Behavior Change Program

University of Michigan

NCT03159247

COMPLETED Phase 4 103 participants

Pre-exposure Prophylaxis Adherence Intervention for MSM

Fenway Community Health

NCT01632397

COMPLETED NA 97 participants

Health Improvement for Baltimore Youth

Johns Hopkins University

NCT02624193

COMPLETED NA 87 participants

Assessing Illustrated Medication Labels

Wayne Sanderson

NCT07389317

COMPLETED NA 80 participants

Mobile Health Application to Improve HIV Medication Adherence

Rhode Island Hospital

NCT02676128

COMPLETED 75 participants

Insulin Dosing Practices in Persons With Diabetes on Multiple Daily Injections

Joslin Diabetes Center

NCT02914730

COMPLETED NA 73 participants

Phenotyping Adherence Through Technology-Enabled Reports and Navigation

Northwestern University

NCT05766423

COMPLETED NA 71 participants

Evaluation of HepCure Toolkit to Improve Harvoni Adherence

Icahn School of Medicine at Mount Sinai

NCT02740556

COMPLETED NA 70 participants

ARemind: A Personalized System to Remind for Adherence

Dimagi

NCT01229722

COMPLETED NA 60 participants

Smart Capsule for Automatic Adherence Monitoring

Medical University of South Carolina

NCT02344238

COMPLETED NA 60 participants

Behavioral Economics to Improve Antihypertensive Therapy Adherence

Cedars-Sinai Medical Center

NCT04029883

COMPLETED Phase 1 43 participants

Pilot Program to Improve Statin Adherence and Lower Cholesterol in Older Adults

University of Missouri-Columbia

NCT01227330

COMPLETED Phase 1 42 participants

A BCT Intervention for Medication Adherence Among Individuals on Statins

Northwell Health

NCT05273736

COMPLETED NA 35 participants

Text Messages for Liver Transplant Recipients

Children's Hospital Los Angeles

NCT04995770

COMPLETED NA 30 participants

A Concierge Model of CAE Plus LAI in Individuals With Schizophrenia at Risk for Treatment Non-adherence and Homelessness

University Hospitals Cleveland Medical Center

NCT02085447

COMPLETED Early Phase 1 30 participants

Development of a Urine-Based Point-of-Care Test for Adherence to Antiretroviral Drugs

Rhonda Brand

NCT04302896

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Phase Distribution

PhaseTrial count
Phase 1 5
Phase 2 3
Phase 4 1

Named interventions

Most-linked intervention names on Medication Adherence records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

5 Behavioral Change Techniques Behavioral
2 trials
Nudge Behavioral
2 trials
modified Directly Observed Therapy Behavioral
1 trials
General Health Counseling Behavioral
1 trials
Automated Adherence Monitoring System Other
1 trials
MedCHEC Tablet Computer & Adherence Care Behavioral
1 trials
Behavior Economic Incentive Behavioral
1 trials
Living Well with Diabetes Program Behavioral
1 trials

US sites by state

Facility locations filed on Medication Adherence trials. A trial with sites in several states counts in each.

Massachusetts 10 trials
California 9 trials
New York 6 trials
Pennsylvania 5 trials
Maryland 5 trials
Ohio 4 trials
Missouri 4 trials
Kentucky 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Medication Adherence page

53 registered trials, 13 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Medication Adherence condition card totals 53 registered trials; most-linked intervention 5 Behavioral Change Techniques; top US site state Massachusetts. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.