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2026 data Public-data reference. official source

Medication Adherence

Open-data reference.

53 US clinical trials · 13 currently recruiting

Active & Recent Trials

RECRUITING NA 600 participants

Mobile Cued Adherence Therapy (mCAT) for Blood Pressure Medication

Chad Stecher@asu.edu

NCT06876233

RECRUITING NA 584 participants

Refinement and Testing of Recruitment Methodology for Behavioral Medication Adherence Interventions Using Behavioral Science-based Approaches

Brigham and Women's Hospital

NCT06569290

RECRUITING NA 402 participants

Medication Adherence Program

Tulane University

NCT05183763

RECRUITING NA 360 participants

Technology Enabled Strategies to Promote Treatment Adherence in Liver Transplant

University of Pennsylvania

NCT05260268

RECRUITING NA 328 participants

Improving Medication Adherence Using Family-focused and Literacy-sensitive Strategies

Jia-Rong Wu

NCT05548413

RECRUITING NA 300 participants

Women Focused Encounters for Resilience Independence Strength and Eudaimonia

University of California, San Diego

NCT06216600

RECRUITING NA 217 participants

My Interprofessional Care Team for Adherence and Research Engagement Disparities

University of Arizona

NCT05470439

RECRUITING NA 200 participants

A Mobile Gaming App to Improve Adherence to PrEP

Rhode Island Hospital

NCT05762705

RECRUITING NA 190 participants

MITIGAAT: Multifaceted Intervention to Improve Graft Outcome Disparities in African American Kidney Transplants

Medical University of South Carolina

NCT06023615

RECRUITING NA 150 participants

The Youth Opioid Recovery Support (YORS) Intervention

Potomac Health Foundations

NCT04173416

RECRUITING Phase 2 110 participants

An Integrated Intervention Using a Pill Ingestible Sensor System

University of California, Los Angeles

NCT06480578

RECRUITING NA 108 participants

Reducing Psychological Barriers to PrEP Persistence Among Pregnant and Postpartum Women in Cape Town, South Africa

Boston University Charles River Campus

NCT05624931

RECRUITING NA 100 participants

1MoreStep: An Intervention to Increase HIV Care Engagement and Reduce Intimate Partner Violence Among Black Women Living With HIV

Johns Hopkins University

NCT05608421

ACTIVE NOT RECRUITING NA 239 participants

PrEP Affect Regulation Treatment Innovation

Florida International University

NCT04899024

ACTIVE NOT RECRUITING 150 participants

Medication Adherence in Patients With Sarcoidosis

Johns Hopkins University

NCT05438095

ACTIVE NOT RECRUITING NA 150 participants

Assessment of Medherent Medication Management Device and Adherence Platform

Terrapin Pharmacy

NCT03775044

ACTIVE NOT RECRUITING NA 75 participants

Implementation Strategies for Monitoring Adherence in Real Time

Abramson Cancer Center at Penn Medicine

NCT04347161

ACTIVE NOT RECRUITING NA 70 participants

REACH-Es: Adapting a Digital Health Tool to Improve Diabetes Medication Adherence Among Latino Adults

Massachusetts General Hospital

NCT06000813

ACTIVE NOT RECRUITING Phase 2 70 participants

Preventing Medication Mismanagement in People Living with Dementia Through Automated Medication Dispensing with Facial Recognition and Video Observation

HiDO Technologies

NCT06691256

ACTIVE NOT RECRUITING NA 40 participants

MHealth Incentivized Adherence Plus Patient Navigation

University of Washington

NCT06027814

COMPLETED NA 65,177 participants

Social Norms, Messengers, and Processing Fluency to Increase Hypertension Medication Adherence

Brigham and Women's Hospital

NCT06066541

COMPLETED NA 9,501 participants

Personalized Patient Data and Behavioral Nudges to Improve Adherence to Chronic Cardiovascular Medications

University of Colorado, Denver

NCT03973931

COMPLETED NA 1,726 participants

Addressing Antihypertensive Medication Adherence Through EHR-enabled Teamlets in Primary Care

NYU Langone Health

NCT05349422

COMPLETED NA 755 participants

Patient-Centered Models of HCV Care for People Who Inject Drugs

Prisma Health-Upstate

NCT02824640

COMPLETED NA 712 participants

Evaluation of an Interactive Opioid Risk Education Program (STOMP) for Parents

University of Michigan

NCT03287622

COMPLETED Phase 1 600 participants

Nurse Delivered Cell Phone Adherence Intervention (Pick It UP)

University of Connecticut

NCT01359280

COMPLETED NA 473 participants

Improving Medication Adherence in the Alabama Black Belt

Weill Medical College of Cornell University

NCT02274844

COMPLETED NA 371 participants

Medications for Chronic HIV: Education and Collaboration

Boston University

NCT01038076

COMPLETED 292 participants

Identifying Factors Underlying the Discontinuation of Triptans

Mayo Clinic

NCT00890357

COMPLETED 276 participants

Antibiotic Adherence Practices in Dermatologic Surgery

University of Pennsylvania

NCT04117724

COMPLETED NA 200 participants

Federal Study of Adherence to Medications in the Elderly (FAME)

Walter Reed Army Medical Center

NCT00393419

COMPLETED Phase 2 176 participants

Study to Test the Efficacy of Online Education to Increase Safe Use of Opioid Medication.

Inflexxion

NCT01770314

COMPLETED NA 174 participants

Improving HIV and Alcohol-Related Outcomes Among HIV+ Persons in Clinic Settings

Hunter College of City University of New York

NCT02390908

COMPLETED NA 170 participants

Intervention to Improve Adherence in Teen Kidney Transplant

McGill University Health Centre/Research Institute of the McGill University Health Centre

NCT01356277

COMPLETED NA 107 participants

The eyeGuide: Improving Glaucoma Self-management With a Personalized Behavior Change Program

University of Michigan

NCT03159247

COMPLETED Phase 4 103 participants

Pre-exposure Prophylaxis Adherence Intervention for MSM

Fenway Community Health

NCT01632397

COMPLETED NA 97 participants

Health Improvement for Baltimore Youth

Johns Hopkins University

NCT02624193

COMPLETED NA 87 participants

Assessing Illustrated Medication Labels

Wayne Sanderson

NCT07389317

COMPLETED NA 80 participants

Mobile Health Application to Improve HIV Medication Adherence

Rhode Island Hospital

NCT02676128

COMPLETED 75 participants

Insulin Dosing Practices in Persons With Diabetes on Multiple Daily Injections

Joslin Diabetes Center

NCT02914730

COMPLETED NA 73 participants

Phenotyping Adherence Through Technology-Enabled Reports and Navigation

Northwestern University

NCT05766423

COMPLETED NA 71 participants

Evaluation of HepCure Toolkit to Improve Harvoni Adherence

Icahn School of Medicine at Mount Sinai

NCT02740556

COMPLETED NA 70 participants

ARemind: A Personalized System to Remind for Adherence

Dimagi

NCT01229722

COMPLETED NA 60 participants

Smart Capsule for Automatic Adherence Monitoring

Medical University of South Carolina

NCT02344238

COMPLETED NA 60 participants

Behavioral Economics to Improve Antihypertensive Therapy Adherence

Cedars-Sinai Medical Center

NCT04029883

COMPLETED Phase 1 43 participants

Pilot Program to Improve Statin Adherence and Lower Cholesterol in Older Adults

University of Missouri-Columbia

NCT01227330

COMPLETED Phase 1 42 participants

A BCT Intervention for Medication Adherence Among Individuals on Statins

Northwell Health

NCT05273736

COMPLETED NA 35 participants

Text Messages for Liver Transplant Recipients

Children's Hospital Los Angeles

NCT04995770

COMPLETED NA 30 participants

A Concierge Model of CAE Plus LAI in Individuals With Schizophrenia at Risk for Treatment Non-adherence and Homelessness

University Hospitals Cleveland Medical Center

NCT02085447

COMPLETED Early Phase 1 30 participants

Development of a Urine-Based Point-of-Care Test for Adherence to Antiretroviral Drugs

Rhonda Brand

NCT04302896

COMPLETED NA 29 participants

AdheRence to Inhaled Corticosteroids in Asthma

Duke University

NCT03769519

COMPLETED Phase 1 9 participants

Reducing African-American CVD Disparities Intervention Optimization (RADIO) Individuals on Statins

Northwell Health

NCT05954000

COMPLETED 8 participants

Adherence Monitoring For Substance Abuse Clinical Trials

California Pacific Medical Center Research Institute

NCT01867476

Phase Distribution

PhaseTrial count
Early Phase 1 5
Phase 2 3
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Medication Adherence Trial Landscape

ClinicalTrials.gov lists 53 US studies indexed under Medication Adherence, and 13 of those are currently open to recruitment — roughly 25% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Medication Adherence shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 8 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Medication Adherence is led by Johns Hopkins University with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 53 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Medication Adherence?

PlainTrial tracks 53 US clinical trials for Medication Adherence, of which 13 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Medication Adherence?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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