Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

RECRUITING Phase 3

A Phase 3 Study to Assess Efficacy Safety and Tolerability of Remibrutinib in Adult and Adolescent Patients With Moderate to Severe Hidradenitis Suppurativa

NCT06840392 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to establish the efficacy, safety, and tolerability of remibrutinib (LOU064) Dose A and Dose B compared to placebo in participants with moderate to severe hidradenitis suppurativa (HS).

Conditions Studied

Interventions

  • DRUG Remibrutinib Dose A
  • DRUG Remibrutinib Dose B
  • DRUG Placebo 1
  • DRUG Placebo 2

Study Locations (20)

Florida

  • Driven Research — Coral Gables
  • Floridian Research Institute — Miami
  • Sarasota Arthritis Res Ctr — Sarasota
  • University Of South Florida — Tampa

California

  • Ctr for Dermatology Clinical Res — Fremont
  • USC Keck School of Medicine — Los Angeles
  • MedDerm Associates — San Diego

Illinois

  • Northwestern University — Chicago
  • Endeavor Health — Glenview
  • Dundee Dermatology — West Dundee

Arizona

  • CTT Research — Gilbert
  • Ctr Dermatology and Plastic Surgery — Scottsdale

Georgia

  • Emory School of Med Dermatology — Atlanta
  • Atlanta Biomedical Clin Res LLC — Atlanta

Massachusetts

  • Beth Israel Deaconess Med Center — Boston
  • Metro Boston Clinical Partners — Brighton

Alabama

  • Total Skin and Beauty Dermatology Center PC — Birmingham

Indiana

  • Southern IN Clinical Trials — New Albany

Trial Details

FieldValue
Enrollment Target 555 participants
Start Date 2025-03-20
Est. Completion 2028-02-07
Phase Phase 3

Sponsor

Novartis Pharmaceuticals

792 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06840392

The ClinicalTrials.gov registry entry for NCT06840392 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 555 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Novartis Pharmaceuticals, which has 792 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Hidradenitis Suppurativa appearing as the primary indexed condition, and to 4 interventions — of which Remibrutinib Dose A is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06840392 reports 20 study locations spanning 10 distinct geographic areas — top geographies include Florida, California, Illinois. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06840392 about?

NCT06840392 is a clinical study titled "A Phase 3 Study to Assess Efficacy Safety and Tolerability of Remibrutinib in Adult and Adolescent Patients With Moderate to Severe Hidradenitis Suppurativa". The purpose of this study is to establish the efficacy, safety, and tolerability of remibrutinib (LOU064) Dose A and Dose B compared to placebo in participants with moderate to severe hidradenitis suppurativa (HS).

What is the current status of trial NCT06840392?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 555 participants. The study started on 2025-03-20. Estimated completion is 2028-02-07.

What conditions does trial NCT06840392 study?

This clinical trial studies the following conditions: Hidradenitis Suppurativa. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06840392?

The interventions under investigation include: Remibrutinib Dose A (DRUG), Remibrutinib Dose B (DRUG), Placebo 1 (DRUG), Placebo 2 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06840392?

This trial is sponsored by Novartis Pharmaceuticals, which has 792 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06840392 being conducted?

This trial has 20 study locations across Alabama, Arizona, California, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial