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RECRUITING Phase 2

Brivekimig for the Treatment of Moderate to Severe Hidradenitis Suppurativa

NCT07170917 · View on ClinicalTrials.gov ↗

Study Summary

This is a Phase 2b, global, multicenter, sequential, randomized, double-blind, placebo-controlled, parallel group, dose-ranging study in participants with moderate to severe hidradenitis suppurativa. The purpose of the main study is to assess the efficacy and safety of brivekimig in a dose-ranging study of participants with moderate to severe HS. Study details include: The study duration (per participant) will be up to approximately 60 weeks for participants not transitioning into the long-term extension (LTE) study and will be up to approximately 52 weeks for participants transitioning into the LTE study. The randomized treatment duration will be up to approximately 48 weeks.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG Brivekimig

Study Locations (20)

Reg Metropolitana de Santiago

  • Investigational Site Number: 1520003 — Santiago
  • Investigational Site Number: 1520002 — Santiago
  • Investigational Site Number: 1520001 — Santiago
  • Investigational Site Number: 1520005 — Santiago

Florida

  • FXM Clinical Research - Miami- Site Number : 8400017 — Miami
  • FXM Clinical Research Miramar, LLC - Site Number: 8400004 — Miramar

Georgia

  • Advanced Medical Research - Atlanta- Site Number : 8400011 — Atlanta
  • Georgia Skin & Cancer Clinic- Site Number : 8400009 — Savannah

Ontario

  • Lima's Excellence in Allergy and Dermatology Research (LEADER) Inc. — Hamilton
  • Investigational Site Number : 1240009 — Toronto

California

  • Northridge Clinical Trials - Northridge- Site Number : 8400005 — Northridge

Louisiana

  • Louisiana Dermatology Associates- Site Number : 8400006 — Baton Rouge

Rhode Island

  • Clinical Partners- Site Number : 8400002 — Johnston

South Carolina

  • AMR Clinical South Strand, South Carolina- Site Number : 8400018 — Myrtle Beach

Trial Details

FieldValue
Enrollment Target 208 participants
Start Date 2025-11-06
Est. Completion 2028-04-27
Phase Phase 2

Sponsor

Sanofi

275 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07170917

The ClinicalTrials.gov registry entry for NCT07170917 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 208 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Sanofi, which has 275 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Hidradenitis Suppurativa appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT07170917 reports 20 study locations spanning 14 distinct geographic areas — top geographies include Reg Metropolitana de Santiago, Florida, Georgia. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT07170917 about?

NCT07170917 is a clinical study titled "Brivekimig for the Treatment of Moderate to Severe Hidradenitis Suppurativa". This is a Phase 2b, global, multicenter, sequential, randomized, double-blind, placebo-controlled, parallel group, dose-ranging study in participants with moderate to severe hidradenitis suppurativa. The purpose of the main study is to assess the efficacy and safety of brivekimig in a dose-ranging ...

What is the current status of trial NCT07170917?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 208 participants. The study started on 2025-11-06. Estimated completion is 2028-04-27.

What conditions does trial NCT07170917 study?

This clinical trial studies the following conditions: Hidradenitis Suppurativa. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT07170917?

The interventions under investigation include: Placebo (DRUG), Brivekimig (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT07170917?

This trial is sponsored by Sanofi, which has 275 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT07170917 being conducted?

This trial has 20 study locations across California, Florida, Georgia, Louisiana, Rhode Island. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial