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ClinicalTrials.gov 27 recruiting now official registry

Gynecologic Cancer clinical trials

Every US clinical trial registered for Gynecologic Cancer — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

56 US clinical trials · 27 currently recruiting

The research picture

Gynecologic Cancer has 56 registered US clinical trials, 27 of them open to new participants right now — about 48% of the total.

27
recruiting participants now
48%
of trials open to enrollment
2
in Phase 3–4 (later-stage)
6
top sponsor: Dana-Farber Cancer Institute

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING 25,000 participants

Avera Cancer Sequencing and Analytics Protocol (ASAP)

Avera McKennan Hospital & University Health Center

NCT05142033

RECRUITING 8,000 participants

The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study

UMC Utrecht

NCT04075305

RECRUITING NA 1,800 participants

Prospective Evaluation of Pencil Beam Scanning Proton Therapy for Previously Irradiated Tumors

The New York Proton Center

NCT05313191

RECRUITING NA 600 participants

BOLSTER: Learning New Skills to Thrive

Dana-Farber Cancer Institute

NCT06936878

RECRUITING 500 participants

PROmOting Gynecologic Cancer Patients With Frailty to Achieve Functional Recovery

University of California, San Francis

NCT06089083

RECRUITING NA 480 participants

A Study Evaluating the Integrative Medicine at Home (IM@HOME) Program in People With Cancer

Memorial Sloan Kettering Cancer Center

NCT05053230

RECRUITING NA 190 participants

Cryocompression to Reduce Chemotherapy-induced Peripheral Neuropathy in Gynecologic Cancer - COHORT 2

Duke University

NCT06139458

RECRUITING NA 150 participants

Chatbot to Maximize Hereditary Cancer Genetic Risk Assessment

Weill Medical College of Cornell University

NCT05562778

RECRUITING 125 participants

Fatigue and Molecular Mechanisms in Cancer Patients Receiving CCRT

University of California, San Francis

NCT06633224

RECRUITING NA 120 participants

Mindfulness in Endometrial and Cervical Cancer

St. Louis University

NCT04512144

RECRUITING NA 100 participants

The Florida ASCENT Study

University of Florida

NCT07042243

RECRUITING Phase 2 86 participants

The Use of Guarana to Treat Fatigue in Patients With Neuroendocrine Tumors and Gynecologic Cancers (Guarana Fatigue)

University of Utah

NCT07151391

RECRUITING NA 64 participants

Improve Cancer-related Cognitive Impairment

University of Alabama at Birmingham

NCT05864274

RECRUITING NA 60 participants

Exercise and Movement to Enhance Resiliency in Cancer Patients

University of California, San Francis

NCT06809933

RECRUITING Phase 2 51 participants

Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial

University of California, Irvine

NCT06580002

RECRUITING Phase 2 50 participants

Clinical Investigation of the Effects of Semiconductor Embedded Therapeutic Garments on Cancer-related Cognitive Impairment in Breast and Gynecological Cancer Patients

University of Utah

NCT07173101

RECRUITING NA 50 participants

Molecular and Cellular Profiling of Uterine Lavage Collected During Gynecologic Surgery

Stanford University

NCT07044505

RECRUITING Phase 1 37 participants

Cabozantinib and Dostarlimab in Recurrent Gynecologic Carcinosarcoma

University of Alabama at Birmingham

NCT05559879

RECRUITING Phase 3 34 participants

Guided Meditation During Radiation Therapy for Breast and Gynecological Malignancies

University of Utah

NCT07166042

RECRUITING Phase 1 33 participants

Intraperitoneal FT536 in Recurrent Ovarian, Fallopian Tube, and Primary Peritoneal Cancer

Masonic Cancer Center, University of Minnesota

NCT06342986

RECRUITING Phase 2 32 participants

Belzutifan in Recurrent Clear Cell Carcinoma of Gynecologic Origin

Dana-Farber Cancer Institute

NCT06677190

RECRUITING 30 participants

Gut Microbiome and Treatment for Gynecological Cancer Patients Receiving Immunotherapy

Viome

NCT04957511

RECRUITING Phase 2 24 participants

Riluzole For Preventing Cognitive Dysfunction in Ca Pts Receiving Chemo (REFOCUS): Pilot Trial

University of California, Irvine

NCT07447050

RECRUITING Phase 1 20 participants

Novel Imaging Technique to Assess Gynecologic Cancer

Memorial Sloan Kettering Cancer Center

NCT04893434

RECRUITING NA 19 participants

Transcranial Magnetic Stimulation for Chemotherapy-Induced Peripheral Neuropathy in Breast and Gynecologic Cancer Survivors

University of Utah

NCT07120100

RECRUITING NA 16 participants

Activity Coaching During Pelvic Radiation Therapy

Inova Health Care Services

NCT06746428

RECRUITING Phase 1 11 participants

Brodalumab in the Treatment of Immune-Related Adverse Events

Brian Henick, MD

NCT06673329

ACTIVE NOT RECRUITING NA 800 participants

Pathways to Advance Targeted and Helpful Serious Illness Conversations (PATH-SIC)

Dana-Farber Cancer Institute

NCT05629065

ACTIVE NOT RECRUITING NA 205 participants

Feasibility Study: IGNITE-TX (Identifying Individuals for Genetic Testing & Treatment) Intervention

M.D. Anderson Cancer Center

NCT05677048

ACTIVE NOT RECRUITING 100 participants

Patient Related Outcomes for Gynecologic Radiation Oncology

UNC Lineberger Comprehensive Cancer Center

NCT04753086

ACTIVE NOT RECRUITING 100 participants

Diet, Hepcidin, and Chemotherapy RDI

George Washington University

NCT06483997

ACTIVE NOT RECRUITING NA 95 participants

Improving Sleep in Gynecologic Cancer Survivors

University of Arizona

NCT05044975

ACTIVE NOT RECRUITING NA 80 participants

The Effect of Low Frequency Soundwave Stimulation on Chemotherapy Induced Peripheral Neuropathy

Augusta University

NCT05980169

ACTIVE NOT RECRUITING NA 60 participants

Psychosexual Educational Partners Program (PEPP)

The University of Tennessee, Knoxville

NCT06253182

ACTIVE NOT RECRUITING NA 53 participants

Clinical Investigation of the da Vinci Surgical System

Intuitive Surgical

NCT05682742

ACTIVE NOT RECRUITING NA 49 participants

Optimizing Brachytherapy Application and Delivery With MRI Guidance for Gynecologic Cancer

Dana-Farber Cancer Institute

NCT03277469

ACTIVE NOT RECRUITING Phase 2 48 participants

Acupuncture Pilot Study for Cancer-related Cognitive Function

Memorial Sloan Kettering Cancer Center

NCT04007770

ACTIVE NOT RECRUITING NA 45 participants

An Intervention to Help Patients and Caregivers Manage Stress and Improve Communication Skills When Talking About Cancer

Memorial Sloan Kettering Cancer Center

NCT03794635

ACTIVE NOT RECRUITING Phase 1 39 participants

Evaluating Safety and Biomarkers Using DK210 (EGFR) for Locally Advanced or Metastatic EGFR+ Tumors

DEKA Biosciences

NCT05704985

ACTIVE NOT RECRUITING Phase 2 30 participants

Pembrolizumab and Lenvatinib in Clear Cell Ovarian Cancer

Elizabeth K. Lee MD

NCT05296512

ACTIVE NOT RECRUITING NA 30 participants

Journey Ahead: Enhancing Coping and Communication for Women Diagnosed With Gynecological Cancer

Rutgers, The State University of New Jersey

NCT05220033

ACTIVE NOT RECRUITING Phase 2 19 participants

Study of Intravenous and Intraperitoneal Paclitaxel and Oral Nilotinib for Peritoneal Carcinomatosis From Colorectal, Appendiceal, Small Bowel, Gastric, Cholangiocarcinoma, Breast, Ovarian, or Other Gynecologic Primary Cancer

National Cancer Institute (NCI)

NCT05185947

ACTIVE NOT RECRUITING Phase 1 18 participants

Adoptive Cell Therapy Using Cancer Specific CD8+ Tumor Infiltrating Lymphocytes in Adult Patients With Solid Tumors

AgonOx

NCT05902520

ACTIVE NOT RECRUITING NA 12 participants

Improving Women's Function After Pelvic Radiation

Duke University

NCT04544735

ACTIVE NOT RECRUITING 10 participants

A Pilot Study of Quantitative Tumor Oxygen Measurements in Cervical Cancer

Dana-Farber Cancer Institute

NCT03970083

COMPLETED NA 1,053 participants

Effectiveness of Lay Navigators in Meeting Cancer Patients' Non-Clinical Needs: A Pilot Study

Stanford University

NCT03245788

COMPLETED Phase 3 464 participants

Prasterone (Dehydroepiandrosterone) in Treating Postmenopausal Cancer Survivors With Vaginal Symptoms

Alliance for Clinical Trials in Oncology

NCT01376349

COMPLETED Phase 2 400 participants

Oral Apixaban (Eliquis) Versus Enoxaparin (Lovenox) for Thromboprophylaxis in Women With Suspected Pelvic Malignancy

University of Colorado, Denver

NCT02366871

COMPLETED 160 participants

Assessment of Sexual Dysfunction, Depression and Anxiety in Underserved, Minority Gynecologic Cancers Patients

M.D. Anderson Cancer Center

NCT01031602

COMPLETED NA 150 participants

Patient-Centered Intervention to Reduce Cancer Patients' Financial Toxicity

Washington University School of Medicine

NCT04314284

COMPLETED NA 102 participants

The HOPE Trial and the SMART Study

Dana-Farber Cancer Institute

NCT03022032

COMPLETED NA 102 participants

Improving Quality of Life Using Patient Reported Outcomes Measures Post-operative Via Text Messaging

University of Michigan Rogel Cancer Center

NCT04852471

COMPLETED Phase 2 75 participants

Transversus Abdominis Plane Blocks for Patients Undergoing Robotic Gynecologic Oncology Surgery

University of Wisconsin, Madison

NCT01444924

COMPLETED NA 32 participants

Women's Health Communication Study

Fox Chase Cancer Center

NCT05359952

COMPLETED NA 18 participants

Developing a Psychosexual Educational Partners Program: PEPP A Feasibility Study

University of Michigan Rogel Cancer Center

NCT05070299

COMPLETED 15 participants

[18F] Flourothymidine (FLT) PET/CT Imaging for Gynecologic Cancers

Abramson Cancer Center at Penn Medicine

NCT02108457

Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 10
Phase 3 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Gynecologic Cancer Trial Landscape

ClinicalTrials.gov lists 56 US studies indexed under Gynecologic Cancer, and 27 of those are currently open to recruitment — roughly 48% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Gynecologic Cancer shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 16 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Gynecologic Cancer is led by Dana-Farber Cancer Institute with 6 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 56 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Gynecologic Cancer?

PlainTrial tracks 56 US clinical trials for Gynecologic Cancer, of which 27 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Gynecologic Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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