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The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study
NCT04075305 · View on ClinicalTrials.gov ↗
Study Summary
The Multi-OutcoMe EvaluatioN of radiation Therapy Using the Unity MR-Linac Study (MOMENTUM) is a multi-institutional, international registry facilitating evidenced based implementation of the Unity MR-Linac technology and further technical development of the MR-Linac system with the ultimate purpose to improve patients' survival, local, and regional tumor control and quality of life.
Conditions Studied
Interventions
- RADIATION Radiation therapy
Study Locations (18)
Other
- Austin Health - Olivia Newton-John Cancer Wellness and Research Centre — Melbourne
- Insitut Jules Bordet — Brussels
- University Health Network - Princess Margaret Cancer Center — Toronto
- Universitätsklinikum Tübingen — Tübingen
- Università degli Studi di Brescia — Brescia
- IRCCS Ospedale Sacro Cuore Don Calabria — Negrar
- Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital — Amsterdam
- Radiotherapiegroep — Deventer
- Radiotherapeutisch Instituut Friesland (RIF) — Leeuwarden
- Radboud UMC — Nijmegen
- University Medical Center Utrecht — Utrecht
- The Royal Marsden and The Institute of Cancer Research National Institute for Health Research Biomedical Research Centre — London
- The Christie National Health Service Foundation Trust — Manchester
Pennsylvania
- Allegheny Health Network — Pittsburgh
Texas
- Md Anderson Cancer Center — Houston
Wisconsin
- Medical College of Wisconsin — Milwaukee
Ontario
- Sunnybrook Health Sciences Centre/Odette Cancer Centre — Toronto
Funen
- Odense Universitetshospital — Odense
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 8,000 participants |
| Start Date | 2019-02-01 |
| Est. Completion | 2030-08-01 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04075305
The ClinicalTrials.gov registry entry for NCT04075305 describes a study currently listed as recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 8,000 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is UMC Utrecht, which has 3 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 10 conditions, with Breast Cancer appearing as the primary indexed condition, and to 1 intervention — of which Radiation therapy is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT04075305 reports 18 study locations spanning 6 distinct geographic areas — top geographies include Other, Pennsylvania, Texas. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT04075305 about?
NCT04075305 is a clinical study titled "The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study". The Multi-OutcoMe EvaluatioN of radiation Therapy Using the Unity MR-Linac Study (MOMENTUM) is a multi-institutional, international registry facilitating evidenced based implementation of the Unity MR-Linac technology and further technical development of the MR-Linac system with the ultimate purpose...
What is the current status of trial NCT04075305?
This trial is currently recruiting. The enrollment target is 8,000 participants. The study started on 2019-02-01. Estimated completion is 2030-08-01.
What conditions does trial NCT04075305 study?
This clinical trial studies the following conditions: Breast Cancer, Prostate Cancer, Brain Tumor, Gynecologic Cancer, Brain Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT04075305?
The interventions under investigation include: Radiation therapy (RADIATION). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT04075305?
This trial is sponsored by UMC Utrecht, which has 3 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT04075305 being conducted?
This trial has 18 study locations across Pennsylvania, Texas, Wisconsin, Ontario, Funen. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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