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Sleep Disturbance
Open-data reference.
57 US clinical trials · 32 currently recruiting
Active & Recent Trials
Enhancing Sleep Quality for Nursing Home Residents With Dementia - R33 Phase
University of Alabama, Tuscaloo
NCT05820919
Improving Maternal Sleep and Mental Health
University of Colorado, Colorado Springs
NCT06544941
Home Apnea Testing in CHildren Trial
Children's Hospital of Philadelphia
NCT05382754
Wellness App for Sleep Disturbance in Hematological Cancer Patients
The University of Texas Health Science Center at San Antonio
NCT05294991
UCLA REST Study (REsearch on Sleep Techniques)
University of California, Los Angeles
NCT05576090
Medications for Opioid Use Disorder Photosensitive Retinal Ganglion Cell Function, Sleep, and Circadian Rhythms: Implications for Treatment
University of Alabama at Birmingham
NCT06104280
REmotely-delivered Supportive Programs for Improving Surgical Pain and disTrEss
Wake Forest University Health Sciences
NCT05625360
RCT of a Weighted Blanket to Reduce Pain in Veterans With Chronic Pain
VA Office of Research and Development
NCT05963607
Sleep Disturbance and Emotion Regulation Brain Dysfunction as Mechanisms of Neuropsychiatric Symptoms in Alzheimer's Dementia
Stanford University
NCT04100057
Personalized Approach To Habits - Sleep
KDH Research & Communication
NCT07029919
SPARK Healthy Sleep
Indiana University
NCT07119268
Sleep and Central Auditory Processing Disorder in Autism Spectrum Disorder
Loma Linda University
NCT06059352
Sleep Promotion Program Primary Care
University of Pittsburgh
NCT06240325
Evaluating the Effects of Tasimelteon in Individuals With Autism Spectrum Disorder (ASD) and Sleep Disturbances
Vanda Pharmaceuticals
NCT05361707
Targeting Cognition in Early Alzheimer's Disease by Improving Sleep With Trazodone
Johns Hopkins University
NCT05282550
A Multi-Modal Combination Intervention to Promote Cognitive Function in Older Intensive Care Unit Survivors
University of Washington
NCT06411561
A Study to Evaluate the Effects of a Supplement on the Side Effects Associated With Stimulant Medications
Outliers
NCT07380412
Transdiagnostic Sleep and Circadian Intervention + Bright Light in Adolescents With Elevated Depression (TranS-C+BL)
University of Pittsburgh
NCT06963463
Sleep Enhancement for Older Adults Living With Memory Loss And Their Care Partners
Emory University
NCT06250725
Nuestro Sueno: Cultural Adaptation of a Couples Intervention to Improve PAP Adherence and Sleep Health Among Latino Couples With Implications for Alzheimer's Disease Risk
University of Utah
NCT06649929
The Iowa ACEs and Sleep Cohort and Manipulating Sleep in Young Adults With ACEs Studies
Nathaniel Jenkins
NCT06454344
The Dream Team: Testing Implementation of a Sleep Intervention for Perinatal Women Delivered by Direct Care Workers
Rhode Island Hospital
NCT06737055
Optimizing Attention and Sleep Intervention Study
University of Pittsburgh
NCT05683756
Using Dupilumab to Improve Circadian Function, Sleep and Pruritus in Children With Moderate/Severe Atopic Dermatitis
Northwestern University
NCT05042258
Art Therapy and Emotional Well Being in Military Populations With Posttraumatic Stress Symptoms
Walter Reed National Military Medical Center
NCT05414708
VR-PMR for Post-Burn Symptoms
Johns Hopkins University
NCT07317271
PICU-related Sleep and Circadian Dysregulation Pilot Study
State University of New York at Buffalo
NCT06505447
Adjunctive Bright Light Therapy for Opioid Use Disorder
Arizona State University
NCT05459922
Mindfulness-Based Intervention for Pain and Sleep in Adolescents and Young Adults With Sickle Cell Disease
University of Illinois at Chicago
NCT07402811
The Acute T-Rex (Timing of Resistance Exercise) Study
University of Utah
NCT06366399
Developing Restful Environments and Management Strategies for Pediatric Stem Cell Transplant Patients
Dana-Farber Cancer Institute
NCT06468618
The Power Down Pilot Study: A Novel Bedtime Manipulation Protocol
University of Pittsburgh
NCT06386029
RECOVER-SLEEP: Platform Protocol, Appendix_B (CPSD)
Duke University
NCT06404112
Auricular Acupuncture for Sleep Disturbances
Paul Crawford
NCT04956341
Improving Sleep in Gynecologic Cancer Survivors
University of Arizona
NCT05044975
Racial Differences in Circadian and Sleep Mechanisms for Nicotine Dependence, Craving, and Withdrawal
University of Alabama at Birmingham
NCT03968900
Sweet Scents to Sweet Dreams
Duquesne University
NCT06247696
Settling Down for Sleep in ADHD: The Impact of Sensory and Arousal Systems on Sleep in ADHD
University of Pittsburgh
NCT06406309
Dry Needling and Therapeutic Exercise on Sleep in Individuals With Chronic Neck Pain and Sleep Disturbance
Mayo Clinic
NCT06275074
Providing Mental Health Precision Treatment
University of Michigan
NCT04342494
RECOVER-SLEEP: Platform Protocol
Duke University
NCT06404086
Radicle Revive 24: A Study of Health and Wellness Products on Menopausal Health and Related Health Outcomes
Radicle Science
NCT06749288
Calm Sleep Coaching
Arizona State University
NCT04566822
Cognitive Behavioral Therapy for Arthritis Pain and Insomnia in Older Adults
University of Washington
NCT01142349
A Brief Patient-Controlled Intervention for a Symptom Cluster in Advanced Cancer
University of Wisconsin, Madison
NCT01954420
A Study of a Sleep Supplement to Improve Sleep in Women Going Through Menopause
Bonafide Health
NCT07375095
Sleep Assessment: The Benefits of Identifying Sleep Disturbance Using a Sleep Questionnaire
University of Texas at Austin
NCT06074224
Sleep Hygiene Intervention on Undergraduate Students' Sleep and Stress
Wayne State University
NCT05933746
Telehealth Delivery of Treatment for Sleep Disturbances in Young Children With Autism Spectrum Disorder
The Cleveland Clinic
NCT03668873
Impact of Bed Provision and Sleep Education
Saint Joseph's University, Philadelphia
NCT04536766
Treatment for Sleep Disturbance in Orthopaedic Trauma Patients
Stanford University
NCT03779243
Clinical Benefits of a Novel Sleep-focused Mind-body Program on Gulf War Illness (GWI) Symptoms
University of Utah
NCT01543997
Stepped-Care Telehealth for Distress in Cancer Survivors
Wake Forest University Health Sciences
NCT03060096
Wearable Neural Interfacing System for REM Sleep Restoration and Enhancement
University of Texas at Austin
NCT07190287
A SMART Design to Improve Sleep Disturbance in Adolescents With Neurodevelopmental Disorders
University of Nebraska
NCT03730194
Sleep Promotion Program Primary Care (SPP PC) Open Trial
University of Pittsburgh
NCT06239792
Implementing Behavioral Sleep Intervention in Urban Primary Care
Children's Hospital of Philadelphia
NCT04046341
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 5 |
| Phase 3 | 2 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Sleep Disturbance Trial Landscape
ClinicalTrials.gov lists 57 US studies indexed under Sleep Disturbance, and 32 of those are currently open to recruitment — roughly 56% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Sleep Disturbance shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 5 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Sleep Disturbance is led by University of Pittsburgh with 6 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 57 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Sleep Disturbance?
PlainTrial tracks 57 US clinical trials for Sleep Disturbance, of which 32 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Sleep Disturbance?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.