Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Sleep Disturbance: early-phase trial registry
32 of 57 indexed Sleep Disturbance trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #249 of 28,707 conditions by registered trial count.
57 US clinical trials · 32 currently recruiting · #249 of 28,707 conditions by registered trial count
Sleep Disturbance: 57 US clinical trials tracked, 32 recruiting.
Sleep Disturbance is the subject of 57 registered US clinical trials on ClinicalTrials.gov, 32 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is University of Pittsburgh, running 6 of these trials.
Enrollment posture brief
Registry condition sleep-disturbance
OPEN 32 | RECR 56% | LATE 3 | EARLY 5 | RANK #249 | SPON 6
Volume-matched condition peers
Nearest open-share peer: Alcohol Intoxication (56% recruiting · 16 trials)
Sleep Disturbance lists 32 open slots (56% of 57 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Sleep Disturbance on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
-
Sleep Disturbance is recruiting above its size-band peers.
32 of 57 indexed trials (56.1%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
-
Sponsorship of Sleep Disturbance trials is spread across many organizations.
University of Pittsburgh accounts for 6 of 57 trials (10.5%). 41 distinct sponsors appear on at least one study for this condition label.
-
Typical Sleep Disturbance enrolment sits around 91 participants.
Median target enrolment is 91 among the 57 trials that report a genuine target (sentinel values excluded). 30 of those (52.6%) plan for fewer than 100 participants.
-
Sleep Disturbance research is mostly interventional.
55 interventional and 2 observational studies make up this index (96.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
57 total, page 1 of 2
Enhancing Sleep Quality for Nursing Home Residents With Dementia - R33 Phase
University of Alabama, Tuscaloo
NCT05820919
Improving Maternal Sleep and Mental Health
University of Colorado, Colorado Springs
NCT06544941
Home Apnea Testing in CHildren Trial
Children's Hospital of Philadelphia
NCT05382754
Wellness App for Sleep Disturbance in Hematological Cancer Patients
The University of Texas Health Science Center at San Antonio
NCT05294991
UCLA REST Study (REsearch on Sleep Techniques)
University of California, Los Angeles
NCT05576090
Medications for Opioid Use Disorder Photosensitive Retinal Ganglion Cell Function, Sleep, and Circadian Rhythms: Implications for Treatment
University of Alabama at Birmingham
NCT06104280
REmotely-delivered Supportive Programs for Improving Surgical Pain and disTrEss
Wake Forest University Health Sciences
NCT05625360
RCT of a Weighted Blanket to Reduce Pain in Veterans With Chronic Pain
VA Office of Research and Development
NCT05963607
Sleep Disturbance and Emotion Regulation Brain Dysfunction as Mechanisms of Neuropsychiatric Symptoms in Alzheimer's Dementia
Stanford University
NCT04100057
Personalized Approach To Habits - Sleep
KDH Research & Communication
NCT07029919
SPARK Healthy Sleep
Indiana University
NCT07119268
Sleep and Central Auditory Processing Disorder in Autism Spectrum Disorder
Loma Linda University
NCT06059352
Sleep Promotion Program Primary Care
University of Pittsburgh
NCT06240325
Evaluating the Effects of Tasimelteon in Individuals With Autism Spectrum Disorder (ASD) and Sleep Disturbances
Vanda Pharmaceuticals
NCT05361707
Targeting Cognition in Early Alzheimer's Disease by Improving Sleep With Trazodone
Johns Hopkins University
NCT05282550
A Multi-Modal Combination Intervention to Promote Cognitive Function in Older Intensive Care Unit Survivors
University of Washington
NCT06411561
A Study to Evaluate the Effects of a Supplement on the Side Effects Associated With Stimulant Medications
Outliers
NCT07380412
Transdiagnostic Sleep and Circadian Intervention + Bright Light in Adolescents With Elevated Depression (TranS-C+BL)
University of Pittsburgh
NCT06963463
Sleep Enhancement for Older Adults Living With Memory Loss And Their Care Partners
Emory University
NCT06250725
Nuestro Sueno: Cultural Adaptation of a Couples Intervention to Improve PAP Adherence and Sleep Health Among Latino Couples With Implications for Alzheimer's Disease Risk
University of Utah
NCT06649929
The Iowa ACEs and Sleep Cohort and Manipulating Sleep in Young Adults With ACEs Studies
Nathaniel Jenkins
NCT06454344
The Dream Team: Testing Implementation of a Sleep Intervention for Perinatal Women Delivered by Direct Care Workers
Rhode Island Hospital
NCT06737055
Optimizing Attention and Sleep Intervention Study
University of Pittsburgh
NCT05683756
Using Dupilumab to Improve Circadian Function, Sleep and Pruritus in Children With Moderate/Severe Atopic Dermatitis
Northwestern University
NCT05042258
Art Therapy and Emotional Well Being in Military Populations With Posttraumatic Stress Symptoms
Walter Reed National Military Medical Center
NCT05414708
VR-PMR for Post-Burn Symptoms
Johns Hopkins University
NCT07317271
PICU-related Sleep and Circadian Dysregulation Pilot Study
State University of New York at Buffalo
NCT06505447
Adjunctive Bright Light Therapy for Opioid Use Disorder
Arizona State University
NCT05459922
Mindfulness-Based Intervention for Pain and Sleep in Adolescents and Young Adults With Sickle Cell Disease
University of Illinois at Chicago
NCT07402811
The Acute T-Rex (Timing of Resistance Exercise) Study
University of Utah
NCT06366399
Developing Restful Environments and Management Strategies for Pediatric Stem Cell Transplant Patients
Dana-Farber Cancer Institute
NCT06468618
The Power Down Pilot Study: A Novel Bedtime Manipulation Protocol
University of Pittsburgh
NCT06386029
RECOVER-SLEEP: Platform Protocol, Appendix_B (CPSD)
Duke University
NCT06404112
Auricular Acupuncture for Sleep Disturbances
Paul Crawford
NCT04956341
Improving Sleep in Gynecologic Cancer Survivors
University of Arizona
NCT05044975
Racial Differences in Circadian and Sleep Mechanisms for Nicotine Dependence, Craving, and Withdrawal
University of Alabama at Birmingham
NCT03968900
Sweet Scents to Sweet Dreams
Duquesne University
NCT06247696
Settling Down for Sleep in ADHD: The Impact of Sensory and Arousal Systems on Sleep in ADHD
University of Pittsburgh
NCT06406309
Dry Needling and Therapeutic Exercise on Sleep in Individuals With Chronic Neck Pain and Sleep Disturbance
Mayo Clinic
NCT06275074
Providing Mental Health Precision Treatment
University of Michigan
NCT04342494
RECOVER-SLEEP: Platform Protocol
Duke University
NCT06404086
Radicle Revive 24: A Study of Health and Wellness Products on Menopausal Health and Related Health Outcomes
Radicle Science
NCT06749288
Calm Sleep Coaching
Arizona State University
NCT04566822
Cognitive Behavioral Therapy for Arthritis Pain and Insomnia in Older Adults
University of Washington
NCT01142349
A Brief Patient-Controlled Intervention for a Symptom Cluster in Advanced Cancer
University of Wisconsin, Madison
NCT01954420
A Study of a Sleep Supplement to Improve Sleep in Women Going Through Menopause
Bonafide Health
NCT07375095
Sleep Assessment: The Benefits of Identifying Sleep Disturbance Using a Sleep Questionnaire
University of Texas at Austin
NCT06074224
Sleep Hygiene Intervention on Undergraduate Students' Sleep and Stress
Wayne State University
NCT05933746
Telehealth Delivery of Treatment for Sleep Disturbances in Young Children With Autism Spectrum Disorder
The Cleveland Clinic
NCT03668873
Impact of Bed Provision and Sleep Education
Saint Joseph's University, Philadelphia
NCT04536766
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 5 |
| Phase 3 | 2 |
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Sleep Disturbance records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Sleep Disturbance trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Sleep Disturbance page
57 registered trials, 32 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 32 Sleep Disturbance trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of Pittsburgh sponsors the most Sleep Disturbance trials on record, review their full trial history before evaluating a specific study. See University of Pittsburgh's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Sleep Disturbance condition card totals 57 registered trials; most-linked intervention Melatonin; top US site state Pennsylvania. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.