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NCT07447050 · ClinicalTrials.gov registry record · Phase 2

Riluzole For Preventing Cognitive Dysfunction in Ca Pts Receiving Chemo (REFOCUS): Pilot Trial

A Phase 2 study of Breast Cancer and Lung Cancer, sponsored by University of California, Irvine.

Recruiting
Registry status
Phase 2
Development phase
24
Enrollment target
1
Study location

NCT07447050 is a Phase 2 study of Breast Cancer and Lung Cancer that is actively recruiting participants, run by University of California, Irvine. The registered enrollment target is 24 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT07447050, a Phase 2 study of Breast Cancer and Lung Cancer, is actively recruiting participants, sponsored by University of California, Irvine.

RECRUITING
Registry status
Phase 2
Development phase
24 participants
Enrollment target
1
Study location

Study Summary

This is a phase II single-arm, Phase 2a, randomized, double-blinded, placebo-controlled pilot clinical trial determining efficacy of riluzole in preventing cognitive dysfunction in subjects with cancer, who are receiving chemotherapy.

Interventions

  • OTHER Placebo
  • DRUG Riluzole

Study Locations (1)

California

  • Chao Family Comprehensive Cancer Center, University of California Irvine - Orange

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2025-12-23
Est. Completion 2028-12-31
Phase Phase 2

Sponsor

University of California, Irvine

368 total trials

What the Registry Record Tells You About NCT07447050

The ClinicalTrials.gov registry entry for NCT07447050 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (99% lower). The listed sponsor is University of California, Irvine, which has 368 total studies on file at ClinicalTrials.gov.

The record links to 10 conditions, with Breast Cancer appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT07447050 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT07447050 about?

NCT07447050 is a clinical study titled "Riluzole For Preventing Cognitive Dysfunction in Ca Pts Receiving Chemo (REFOCUS): Pilot Trial". This is a phase II single-arm, Phase 2a, randomized, double-blinded, placebo-controlled pilot clinical trial determining efficacy of riluzole in preventing cognitive dysfunction in subjects with cancer, who are receiving chemotherapy.

What is the current status of trial NCT07447050?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 24 participants. The study started on 2025-12-23. Estimated completion is 2028-12-31.

What conditions does trial NCT07447050 study?

This clinical trial studies the following conditions: Breast Cancer, Lung Cancer, Colorectal Cancer, Ovarian Cancer, Head and Neck Cancer.

What interventions are being tested in trial NCT07447050?

The interventions under investigation include: Placebo (OTHER), Riluzole (DRUG).

Who is sponsoring clinical trial NCT07447050?

This trial is sponsored by University of California, Irvine, which has 368 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07447050 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.