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ClinicalTrials.gov 25 recruiting now full pipeline

Trauma: full-pipeline trial registry

25 of 57 indexed Trauma trials are currently recruiting.

Corpus placement: #249 of 28,707 conditions by registered trial count.

57 US clinical trials · 25 currently recruiting · #249 of 28,707 conditions by registered trial count

Trauma: 57 US clinical trials tracked, 25 recruiting.

Trauma is the subject of 57 registered US clinical trials on ClinicalTrials.gov, 25 of them currently open to new participants. 5 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is Massachusetts General Hospital, running 5 of these trials.

Enrollment posture brief

Registry condition trauma

OPEN 25 | RECR 44% | LATE 5 | EARLY 5 | RANK #249 | SPON 5

Nearest open-share peer: Small Lymphocytic Lymphoma (44% recruiting · 82 trials)

Sleep Disturbance56.1%Trauma (this)44%Anesthesia43.1%Diabetic Retinopathy25.9%Ocular Hypertension21.1%
Open-enrollment share among volume-matched conditions near Trauma

Trauma lists 25 open slots (44% of 57 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Trauma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Trauma is recruiting above its size-band peers.

    25 of 57 indexed trials (43.9%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Trauma trials is spread across many organizations.

    Massachusetts General Hospital accounts for 5 of 57 trials (8.8%). 47 distinct sponsors appear on at least one study for this condition label.

  3. Typical Trauma enrolment sits around 112 participants.

    Median target enrolment is 112 among the 57 trials that report a genuine target (sentinel values excluded). 25 of those (43.9%) plan for fewer than 100 participants.

  4. Trauma splits between interventional and observational designs.

    36 interventional and 21 observational studies make up this index (63.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 24Phase 32Phase 43

Open and recent trials

57 total, page 1 of 2

RECRUITING NA 1,200 participants

RCT: Early Feeding After PEG Placement

Carilion Clinic

NCT04110613

RECRUITING Phase 2 1,050 participants

CAlcium and VAsopressin Following Injury Early Resuscitation (CAVALIER) Trial

Jason Sperry

NCT05958342

RECRUITING NA 720 participants

Evaluation of the Parenting in the Moment Online Program for Forcibly Displaced Families

Arizona State University

NCT06548126

RECRUITING NA 640 participants

Effectiveness, Implementation, and Cost of Cognitive Processing Therapy in Prisons

University of Arkansas

NCT06923423

RECRUITING Phase 4 606 participants

Lovenox 30 mg Twice Daily (BID) Versus 40 mg Once Daily (QD)

Oregon Health and Science University

NCT02342444

RECRUITING NA 300 participants

Women Focused Encounters for Resilience Independence Strength and Eudaimonia

University of California, San Diego

NCT06216600

RECRUITING 275 participants

The Role of Brain-Bone Marrow-Gut Interaction Following Major Trauma

University of Florida

NCT06606119

RECRUITING NA 240 participants

PRESERVE & CONNECT: Impact Study of the BPC

University of Vermont

NCT06160050

RECRUITING NA 212 participants

Testing FIRST in Youth Outpatient Psychotherapy

Harvard University

NCT04725721

RECRUITING NA 200 participants

Multiphase Optimization Strategy (MOST) for Treating Pediatric Post-traumatic Stress Disorder (PTSD)

University of Rochester

NCT06956781

RECRUITING NA 180 participants

Respiratory Training in the Treatment of Transdiagnostic Pathological Anxiety

University of Texas at Austin

NCT05427708

RECRUITING Phase 2 172 participants

A Clinical Trial of Interventions to Support Family Surrogates of Critically Ill Patients

Weill Medical College of Cornell University

NCT05587517

RECRUITING Phase 1 160 participants

Study of Cannabidiol and Neuroimaging on Stress

Icahn School of Medicine at Mount Sinai

NCT07278505

RECRUITING Phase 4 156 participants

Magnesium Infusion for Pain Management in Critically Ill Trauma Patients

University of California, Davis

NCT04166877

RECRUITING Phase 2 156 participants

MultiStem® for Treatment of Trauma Induced Multiple Organ Failure/Systemic Inflammatory Response Syndrome

Healios K.K.

NCT04533464

RECRUITING NA 120 participants

Effects of Games on Memory Reconsolidation and Trauma Symptoms

University of Texas at Austin

NCT06129435

RECRUITING NA 119 participants

Onyx™ Liquid Embolic IDE Clinical Study

Medtronic Endovascular

NCT06742801

RECRUITING 100 participants

IlluminOss Photodynamic Bone Stabilization System for the Treatment of Impending and Actual Pelvis Fractures

Massachusetts General Hospital

NCT04842266

RECRUITING Phase 4 75 participants

Nonopioid Pain Control Regimen After Open Reduction and Internal Fixation of Traumatic Fractures

Henry Ford Health System

NCT06113211

RECRUITING NA 40 participants

REVIVE: Reducing Exsanguination Via In-Vivo Expandable Foam

Arsenal Medical

NCT02880163

RECRUITING 40 participants

OCT in Open Fracture and Infected Fracture

Dartmouth-Hitchcock Medical Center

NCT05785182

RECRUITING 20 participants

PMCF Study to Evaluate the VERTICALE® Cervical System in Spine Surgery According to Its Intended Use.

Silony Medical

NCT05489822

RECRUITING NA 20 participants

An Imaging Framework for Clinically Testing New Treatments to Prevent Post-traumatic OA

J L Marsh

NCT03809520

RECRUITING 10 participants

Mg OSTEOCRETE Post-Treatment Outcomes

Santiago Lozano-Calderon

NCT06720142

RECRUITING 4 participants

Comparative Outcomes of PCC and Recombinant Activated Factor VIIa in Trauma-Associated Massive Transfusion

Zeliha Alicikus

NCT07290634

ACTIVE NOT RECRUITING 432 participants

Illuminating Neuropsychological Dysfunction and Systemic Inflammatory Mechanisms Gleaned After Hospitalization in Trauma-ICU Study

Vanderbilt University Medical Center

NCT03098459

ACTIVE NOT RECRUITING Phase 2 72 participants

Humacyte Human Acellular Vessel (HAV) in Patients With Vascular Trauma

Humacyte

NCT03005418

ACTIVE NOT RECRUITING NA 50 participants

Analysis of Pedicle Screw Accuracy to Plan Using Medtronic Mazor Robotic System

Ohio State University

NCT05884593

COMPLETED 3,750 participants

Teenage Driving Safety Study: An Emergency Medicine-Trauma Collaborative Study

Lehigh Valley Hospital

NCT01402856

COMPLETED 1,714 participants

Use of Hextend in Trauma

University of Miami

NCT00983281

COMPLETED 846 participants

Maintaining Optimal Trauma Outcomes: Resilience in the Midst of a Ransomware Attack

State University of New York at Buffalo

NCT04881279

COMPLETED 610 participants

Inflammation and the Host Response to Injury (Trauma)

Massachusetts General Hospital

NCT00257231

COMPLETED Phase 3 500 participants

Supplemental Enteral Protein in Critical Illness

University of Washington

NCT03170401

COMPLETED 397 participants

Quantra QStat in Trauma and Liver Transplant

HemoSonics

NCT04312958

COMPLETED 351 participants

Disseminating Child Abuse Clinical Decision Support to Improve Detection, Evaluation and Reporting

University of Pittsburgh

NCT03840798

COMPLETED 280 participants

Inflammation and the Host Response to Injury (Burns)

Massachusetts General Hospital

NCT00257244

COMPLETED NA 254 participants

Frozen Red Blood Cell Transfusions in Trauma Patients

Oregon Health and Science University

NCT01038557

COMPLETED 168 participants

Key Dimensions of PTSD and ED

University of California, Los Angeles

NCT03778307

COMPLETED NA 112 participants

Use of a Non-ICU Specialty Ward For Immediate Post-operative Management of Head and Neck Free Flaps

University of California, Davis

NCT03340038

COMPLETED NA 102 participants

Experiential Training in Eliciting Disclosure & Emotions for Mental Health Trainees

Mark A. Lumley

NCT04511754

COMPLETED NA 100 participants

Using Neuroimaging to Understand Children's Mental Health and Treatment Outcomes

Harvard University

NCT03112265

COMPLETED NA 90 participants

Treatment for Sleep Disturbance in Orthopaedic Trauma Patients

Stanford University

NCT03779243

COMPLETED NA 80 participants

CT C-spine Audit and Feedback

University of Massachusetts, Worcester

NCT05711134

COMPLETED 63 participants

Incidence/Magnitude-Haemorrhagic Progression-Cerebral Contusions and Identification (ID) of Safety Issues After Traumatic Brain Injury

Novo Nordisk A/S

NCT00124293

COMPLETED 62 participants

BVA-200 vs BVA-100 Validation Study

Daxor Corporation

NCT06227819

COMPLETED 52 participants

Longitudinal Gene Expression Profiling in Adults After Traumatic Injury

Stanford University

NCT02656459

COMPLETED NA 50 participants

Brief Intervention for Chronic Pain and History of Stressful Experiences

Brigham and Women's Hospital

NCT06983327

COMPLETED NA 47 participants

A Trauma-Informed Approach for Positive Youth Development for Montana Students

Montana State University

NCT04664855

COMPLETED NA 40 participants

Personalized Nutrition Delivery to Improve Resilience in Older Adult Trauma Patients

Duke University

NCT05544162

COMPLETED NA 40 participants

Trauma Informed Intervention to Support Engagement in HIV Care Among MSM (THRIVE+)

Massachusetts General Hospital

NCT05822206

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Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 4
Phase 3 2
Phase 4 3

Named interventions

Most-linked intervention names on Trauma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Quantra System Diagnostic test
2 trials
RBC units Biological
1 trials
11-gene set Other
1 trials
Life Steps and Sexual Decision-Making Behavioral
1 trials
CBT-TSC Behavioral
1 trials
Melatonin 5mg and Sleep Education Dietary supplement
1 trials
Nutrition supplement - Ensure shakes Dietary supplement
1 trials
Questionnaire self report Other
1 trials

US sites by state

Facility locations filed on Trauma trials. A trial with sites in several states counts in each.

Texas 12 trials
California 12 trials
Massachusetts 9 trials
Florida 7 trials
Ohio 6 trials
New York 6 trials
Colorado 5 trials
Washington 4 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Trauma page

57 registered trials, 25 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Trauma condition card totals 57 registered trials; most-linked intervention Quantra System; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.