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A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin, SGLT2 Inhibitor or Both
NCT06534411 · View on ClinicalTrials.gov ↗
Study Summary
This study will look at how much CagriSema lowers blood sugar and body weight in people with type 2 diabetes. CagriSema is a new investigational medicine. Doctors cannot yet prescribe CagriSema. CagriSema will be compared to a medicine called tirzepatide. Doctors can prescribe tirzepatide in some countries. Participants will either receive CagriSema or tirzepatide. Which treatment the participant will receive is decided by chance. For each participant, the study will last for up to 1 year and 4 months.
Conditions Studied
Interventions
- DRUG Tirzepatide
- DRUG Semaglutide
- DRUG Cagrilintide
Study Locations (20)
California
- Velocity Clin Res-Chula Vista — Chula Vista
- John Muir Physicians Network — Concord
- Diabetes & Endocrine Specialists - La Mesa — La Mesa
- Velocity Clin Research LA — Los Angeles
- Desert Oasis Healthcare — Palm Springs
- Velocity Clin Res Santa Ana — Santa Ana
- Velocity Clin Res - Panorama — Van Nuys
Florida
- Tampa Bay Medical Research — Clearwater
- AGA Clinical Trial — Hialeah
- Clinical Trial Services Corp — Miami
- Bioclinical Research Alliance — Miami
- New Horizon Research Center — Miami
- South Broward Research LLC — Miramar
- West Orange Endocrinology — Ocoee
Arizona
- Velocity Clinical Research-Phoenix — Phoenix
- AES Tucson DRS — Tucson
Alabama
- Cahaba Research — Pelham
Arkansas
- Woodland Int. Research Group — Little Rock
Colorado
- Optumcare Clinical Trials,LLC-Golden — Colorado Springs
District of Columbia
- FEME Medical LLC — Washington D.C.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,023 participants |
| Start Date | 2024-11-05 |
| Est. Completion | 2026-07-14 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06534411
The ClinicalTrials.gov registry entry for NCT06534411 describes a study currently listed as active not recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 1,023 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Novo Nordisk A/S, which has 189 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Diabetes Mellitus, Type 2 appearing as the primary indexed condition, and to 3 interventions — of which Tirzepatide is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06534411 reports 20 study locations spanning 7 distinct geographic areas — top geographies include California, Florida, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06534411 about?
NCT06534411 is a clinical study titled "A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin, SGLT2 Inhibitor or Both". This study will look at how much CagriSema lowers blood sugar and body weight in people with type 2 diabetes. CagriSema is a new investigational medicine. Doctors cannot yet prescribe CagriSema. CagriSema will be compared to a medicine called tirzepatide. Doctors can prescribe tirzepatide in some co...
What is the current status of trial NCT06534411?
This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 1,023 participants. The study started on 2024-11-05. Estimated completion is 2026-07-14.
What conditions does trial NCT06534411 study?
This clinical trial studies the following conditions: Diabetes Mellitus, Type 2. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06534411?
The interventions under investigation include: Tirzepatide (DRUG), Semaglutide (DRUG), Cagrilintide (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06534411?
This trial is sponsored by Novo Nordisk A/S, which has 189 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06534411 being conducted?
This trial has 20 study locations across Alabama, Arizona, Arkansas, California, Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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