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NCT06066528 · ClinicalTrials.gov registry record · Phase 3

A Study to Test Whether Survodutide (BI 456906) Helps People Living With Overweight or Obesity Who Also Have Diabetes to Lose Weight

A Phase 3 study of Obesity and Diabetes Mellitus, Type 2, sponsored by Boehringer Ingelheim.

Active
Registry status
Phase 3
Development phase
755
Enrollment target
20
Study locations

NCT06066528 is a Phase 3 study of Obesity and Diabetes Mellitus, Type 2 that is active but no longer recruiting, run by Boehringer Ingelheim. The registered enrollment target is 755 participants, roughly in line with the 818-participant average among 1,053 other Obesity trials with a reported enrollment target. The trial reports 20 study locations across 13 states.

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The verdict

NCT06066528, a Phase 3 study of Obesity and Diabetes Mellitus, Type 2, is active but no longer recruiting, sponsored by Boehringer Ingelheim.

ACTIVE NOT RECRUITING
Registry status
Phase 3
Development phase
755 participants
Enrollment target
20
Study locations

Study Summary

This study is open to adults who are at least 18 years old and have a body mass index of 27 kg/m² or more. People can take part if they have type 2 diabetes and if they are currently being treated only with diet and exercise or with specific diabetes medications. Only people who have previously not managed to lose weight by changing their diet can participate. The purpose of this study is to find out whether a medicine called survodutide (BI 456906) helps people living with overweight or obesity who also have diabetes to lose weight. Participants are divided into 3 groups by chance, like drawing names from a hat. 2 groups get different doses of survodutide and 1 group gets placebo. Placebo looks like survodutide but does not contain any medicine. Every participant has a 2 in 3 chance of getting survodutide. Participants inject survodutide or placebo under their skin once a week for about one and a half years. In addition to the study medicine, all participants receive counselling to make changes to their diet and to exercise regularly. Participants are in the study for about 1 year and 7 months. During this time, it is planned that participants visit the study site up to 14 times and receive 6 phone calls by the site staff. The doctors check participants' health and take note of any unwanted effects. The study staff also regularly measure participants' body weight. The results are compared between the groups to see whether the treatment works.

Interventions

  • COMBINATION_PRODUCT Placebo
  • COMBINATION_PRODUCT Survodutide

Study Locations (20)

Florida

  • Alliance for Multispecialty Research, LLC - Doral - Doral
  • University of Florida - Gainesville
  • East Coast Institute for Research, LLC - Jacksonville - Jacksonville
  • New Horizon Research Center-Miami-69732 - Miami
  • West Orange Endocrinology - Ocoee

California

  • Encompass Clinical Research, Spring Valley - Spring Valley
  • Diablo Clinical Research - Walnut Creek

Kentucky

  • AMR Lexington - Lexington
  • L-MARC Research Center - Louisville

New Jersey

  • Walgreens Clinical Trials-Atlantic City-69647 - Atlantic City
  • Walgreens - Perth Amboy - Site 4544 - Perth Amboy

Alabama

  • Pinnacle Research Group, LLC - Anniston

Arizona

  • EmVenio Research-Atlanta-69582 - Phoenix

Georgia

  • Emory University - Atlanta

Hawaii

  • East-West Medical Research - Honolulu

Trial Details

FieldValue
Enrollment Target 755 participants
Start Date 2023-11-27
Est. Completion 2026-04-03
Phase Phase 3

Sponsor

Boehringer Ingelheim

515 total trials

What the Registry Record Tells You About NCT06066528

The ClinicalTrials.gov registry entry for NCT06066528 describes a study currently listed as active not recruiting, categorized as Phase 3. The registered enrollment target is 755 participants, a figure that helps gauge the scale of data the investigators plan to collect, roughly in line with the 818-participant average among 1,053 other Obesity trials with a reported enrollment target. The listed sponsor is Boehringer Ingelheim, which has 515 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Obesity appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT06066528 reports 20 study locations spanning 13 distinct geographic areas - top geographies include Florida, California, Kentucky.

Frequently Asked Questions

What is clinical trial NCT06066528 about?

NCT06066528 is a clinical study titled "A Study to Test Whether Survodutide (BI 456906) Helps People Living With Overweight or Obesity Who Also Have Diabetes to Lose Weight". This study is open to adults who are at least 18 years old and have a body mass index of 27 kg/m² or more. People can take part if they have type 2 diabetes and if they are currently being treated only with diet and exercise or with specific diabetes medications. Only people who have previously not ...

What is the current status of trial NCT06066528?

This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 755 participants. The study started on 2023-11-27. Estimated completion is 2026-04-03.

What conditions does trial NCT06066528 study?

This clinical trial studies the following conditions: Obesity, Diabetes Mellitus, Type 2.

What interventions are being tested in trial NCT06066528?

The interventions under investigation include: Placebo (COMBINATION_PRODUCT), Survodutide (COMBINATION_PRODUCT).

Who is sponsoring clinical trial NCT06066528?

This trial is sponsored by Boehringer Ingelheim, which has 515 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06066528 being conducted?

This trial has 20 study locations across Alabama, Arizona, California, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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