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NCT05544266 · ClinicalTrials.gov registry record

Rare and Atypical Diabetes Network

A clinical trial of Diabetes Mellitus and Metabolic Disease, sponsored by University of South Florida.

Recruiting
Registry status
2,000
Enrollment target
13
Study locations

NCT05544266: Recruiting study of Diabetes Mellitus and Metabolic Disease, sponsored by University of South Florida.

NCT05544266 is a study of Diabetes Mellitus and Metabolic Disease that is actively recruiting participants, run by University of South Florida. The registered enrollment target is 2,000 participants, roughly in line with the 1,858-participant average among 208 other Diabetes Mellitus trials with a reported enrollment target. The trial reports 13 study locations across 12 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05544266, a study of Diabetes Mellitus and Metabolic Disease, is actively recruiting participants, sponsored by University of South Florida.

RECRUITING
Registry status
2,000 participants
Enrollment target
13
Study locations

Study Summary

RADIANT is a network of 14 clinical sites and several laboratories dedicated to the study of atypical diabetes. The objective of this study is to define new forms of diabetes and the unique mechanisms underlying these forms of atypical diabetes. The specific aims are to: 1. Identify and enroll individuals and families with undiagnosed rare and atypical forms of diabetes. 2. Determine the etiologic basis of the metabolic disorder among individuals and families with novel forms of rare and atypical diabetes. 3. Understand the pathophysiology of individuals and families with novel forms of rare and atypical forms of diabetes.

Primary Outcome

Deeper phenotyping methods include both clinical and laboratory assessments. Clinical data includes anthropometric and biometric data, medical histories, and standard questionnaires (ASA24, PROMIS, environmental exposures depression and anxiety). Laboratory data includes WGS, transcriptomics, metabolomics, mitochondrial sequencing, Oral Glucose Tolerance Test (OGTT), and Islet autoantibodies. Clustering methods will be used to define cohorts of similar diabetes genotypes and phenotypes based on

Conditions Studied

Diabetes Mellitus Metabolic Disease Glucose Metabolism Disorders Glucose Intolerance Endocrine System Diseases Diabetes Mellitus Progression Endocrine; Complications

Study Locations (13)

New York

  • SUNY Downstate Health Sciences University - Brooklyn
  • Columbia University - New York

Colorado

  • University of Colorado- Denver - Aurora

Illinois

  • University of Chicago - Chicago

Indiana

  • Indiana University - Indianapolis

Maryland

  • University of Maryland - Baltimore

Massachusetts

  • Massachusetts General Hospital (MGH) - Boston

Michigan

  • University of Michigan - Ann Arbor

Missouri

  • Washington University in St. Louis - St Louis

Trial Details

FieldValue
Enrollment Target 2,000 participants
Start Date 2020-09-30
Est. Completion 2030-09
University of South Florida

252 total trials

What NCT05544266 shows while recruiting

NCT05544266 is an observational study that tracks outcomes without assigning an intervention. Its 2,000 participants enrollment target places it among the larger protocols in the corpus, roughly in line with the 1,858-participant average among 208 other Diabetes Mellitus trials with a reported enrollment target.

The record links to 7 conditions, with Diabetes Mellitus appearing as the primary indexed condition, and to 0 interventions.

NCT05544266 lists 13 locations in 12 states (New York, Colorado, Illinois).

Frequently Asked Questions

What is clinical trial NCT05544266 about?

NCT05544266 is a clinical study titled "Rare and Atypical Diabetes Network". RADIANT is a network of 14 clinical sites and several laboratories dedicated to the study of atypical diabetes. The objective of this study is to define new forms of diabetes and the unique mechanisms underlying these forms of atypical diabetes. The specific aims are to: 1. Identify and enroll ind...

What is the current status of trial NCT05544266?

This trial is currently recruiting. The enrollment target is 2,000 participants. The study started on 2020-09-30. Estimated completion is 2030-09.

What conditions does trial NCT05544266 study?

This clinical trial studies the following conditions: Diabetes Mellitus, Metabolic Disease, Glucose Metabolism Disorders, Glucose Intolerance, Endocrine System Diseases.

Who is sponsoring clinical trial NCT05544266?

This trial is sponsored by University of South Florida, which has 252 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05544266 being conducted?

This trial has 13 study locations across Colorado, Illinois, Indiana, Maryland, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Diabetes Mellitus

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05544266's enrollment target sits among peer trials

2,000 19th of 208 higher than 189 of 208 other Diabetes Mellitus trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Diabetes Mellitus trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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More recruiting context for NCT05544266

Source: ClinicalTrials.gov NCT05544266, the US trial registry maintained by the National Library of Medicine. NCT05544266 (large enrollment · multi site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.