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Diabetes Mellitus: full-pipeline trial registry
49 of 210 indexed Diabetes Mellitus trials are currently recruiting.
Corpus placement: #44 of 28,707 conditions by registered trial count.
210 US clinical trials · 49 currently recruiting · #44 of 28,707 conditions by registered trial count
Diabetes Mellitus: 210 US clinical trials tracked, 49 recruiting.
Diabetes Mellitus is the subject of 210 registered US clinical trials on ClinicalTrials.gov, 49 of them currently open to new participants. 26 are in Phase 3-4 (later-stage) and 32 in Phase 1-2 (earlier-stage). The most active sponsor is Takeda, running 8 of these trials.
Enrollment posture brief
Registry condition diabetes-mellitus
OPEN 49 | RECR 23% | LATE 26 | EARLY 32 | RANK #44 | SPON 8
Volume-matched condition peers
Nearest open-share peer: Alzheimers Disease (23% recruiting · 150 trials)
Diabetes Mellitus lists 49 open slots (23% of 210 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Diabetes Mellitus on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Diabetes Mellitus is recruiting below its size-band peers.
49 of 210 indexed trials (23.3%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Diabetes Mellitus trials is spread across many organizations.
Takeda accounts for 8 of 210 trials (3.8%). 123 distinct sponsors appear on at least one study for this condition label.
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Typical Diabetes Mellitus enrolment sits around 136 participants.
Median target enrolment is 136 among the 209 trials that report a genuine target (sentinel values excluded). 86 of those (41.1%) plan for fewer than 100 participants.
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Diabetes Mellitus research is mostly interventional.
175 interventional and 35 observational studies make up this index (83.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
210 total, page 2 of 5
Cardiovascular Health Study (CHS)
National Heart, Lung, and Blood Institute (NHLBI)
NCT00005133
Eat Well Produce Benefit for Diabetes and Food Insecurity
Duke University
NCT05896644
SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN
Medtronic Vascular
NCT05198674
Dissemination of the Cardiovascular Risk Service
Korey Kennelty
NCT03660631
Biological Sample Repository for Gastrointestinal Disorders
Pichamol Jirapinyo, MD, MPH
NCT05874726
Eat, Move, Live Program for the Reduction of Cancer and Chronic Disease Risk in Underserved Communities
City of Hope Medical Center
NCT05414396
Oral Anti Diabetic Agents in the Hospital
Emory University
NCT04416269
Texting for Diabetes
St. Louis University
NCT03025984
The REST Study for CGM Use in Older Adults With Insulin-treated Diabetes
Joslin Diabetes Center
NCT05337826
People With CHC Who Achieved a Sustained Virological Response Following Therapy With Direct Acting Antiviral Agents
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT03520660
Black Girls Move Physical Activity and Improving Dietary Intake Among Black Adolescent Daughters
Rush University Medical Center
NCT05433415
Glucose Metabolism in Sickle Cell Disease
University of Illinois at Chicago
NCT02922296
A Sugar-Sweetened Beverage Reduction Intervention for Native American Men
Roswell Park Cancer Institute
NCT06029517
Continuous Glucose Monitoring of Hospitalized Patients With Diabetes
Baylor Research Institute
NCT04230694
Glycemic Emergency Management (GEM); An App for Rapid Response to Hypoglycemic and Hyperglycemic Situations
Marshall University
NCT02336217
Food is Medicine vs Lifestyle Medicine For Cardiovascular Kidney Metabolic (CKM) Syndrome
Rutgers, The State University of New Jersey
NCT06461273
Study of a Primary Care Hypoglycemia Prevention Program
Johns Hopkins University
NCT06353217
Community Health Workers in Pediatric Patients With Newly Diagnosed Type 1 Diabetes
Children's Hospital of Philadelphia
NCT04238949
Plant-based Diet for Kidney Transplant Recipients
George Washington University
NCT06186843
Enhancing Mental and Physical Health of Women Veterans
VA Office of Research and Development
NCT05050266
Islet Transplantation Alone (ITA) in Patients With Difficult to Control Type I Diabetes Mellitus Using a Glucocorticoid-free Immunosuppressive Regimen
City of Hope Medical Center
NCT00706420
Evaluation of VLER-Indiana Health Information Exchange Demonstration Project
VA Office of Research and Development
NCT01446705
Evaluating the Navajo Community Outreach and Patient Empowerment (COPE) Program
Brigham and Women's Hospital
NCT03326206
Evaluation of a Dashboard for Diabetes Care Integrated With the Electronic Health Record
University of Utah
NCT03826290
Action to Control Cardiovascular Risk in Diabetes (ACCORD)
National Heart, Lung, and Blood Institute (NHLBI)
NCT00000620
Personalized Patient Data and Behavioral Nudges to Improve Adherence to Chronic Cardiovascular Medications
University of Colorado, Denver
NCT03973931
Blood Glucose Monitoring in Electronic Health Records
Inova Health Care Services
NCT03542487
Improving Diabetes in Primary Care (IMPACT)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00108927
Clinical Decision Support for Medication Management and Adherence
Duke University
NCT00979225
Glucose to Goal: A Model to Support Diabetes Management in Primary Care
University of Pittsburgh
NCT02715934
Improving Quality With Outpatient Decision Support
Agency for Healthcare Research and Quality (AHRQ)
NCT00225628
Study to Evaluate the Effectiveness of a Program Developed to Improve Eye Care for Veterans With Diabetes
US Department of Veterans Affairs
NCT00119535
Randomized Trial of Telemedicine for Diabetes Care
Columbia University
NCT00271739
Diabetes-Depression Care-management Adoption Trial
University of Southern California
NCT01781013
A Clinical Trial Assessing the Impact of the Availability of Inhaled Insulin on Glucose Control
Pfizer
NCT00134147
Efficacy of Alogliptin and Pioglitazone in Subjects With Type 2 Diabetes Mellitus
Takeda
NCT00432276
Integrating Community Health Workers to Improve Diabetes Prevention
NYU Langone Health
NCT03006666
CV Disease in Adolescents With Type 2 Diabetes
Children's Hospital Medical Center, Cincinnati
NCT00114998
Study to Compare Pioglitazone and Rosiglitazone in Subjects With Type 2 Diabetes Mellitus and Dyslipidemia
Takeda
NCT00331487
Cebranopadol Efficacy and Safety in Diabetic Patients Suffering From Chronic Pain Caused by Damage to the Nerves
Tris Pharma
NCT01939366
Phase 3 28-Week Study With 24-Week and 52-week Extension Phases to Evaluate Efficacy and Safety of Exenatide Once Weekly and Dapagliflozin Versus Exenatide and Dapagliflozin Matching Placebo
AstraZeneca
NCT02229396
Meals MATTER: A Trial of Medically Tailored Meals 2 Weeks vs. 4 Weeks Post Hospital Discharge
Kaiser Permanente
NCT04351880
Evaluation of the Analytical Performance of ALLEGRO™ Instrument
Nova Biomedical
NCT04096313
Screening for Patients Needing Kidney, Kidney-Pancreas, or Islet-Cell Transplant
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00001859
Efficacy and Safety of Pioglitazone and Metformin Combination Therapy in Treating Type 2 Diabetes Mellitus.
Takeda
NCT00727857
Effect of Care Management on Diabetes Outcomes
Minneapolis Veterans Affairs Medical Center
NCT00569556
Multidisciplinary Inpatient Palliative Care Intervention
Kaiser Permanente
NCT00325611
Efficacy Study of Pioglitazone Compared to Glimepiride on Coronary Atherosclerotic Disease Progression in Subjects With Type 2 Diabetes Mellitus
Takeda
NCT00225277
User Evaluation of the Invasive Component of the CNOGA TensorTip COMBO GLUCOMETER (CoG)
Sciema UG
NCT03870971
Efficacy and Safety of Alogliptin Combined With Metformin in Participants With Type 2 Diabetes Mellitus
Takeda
NCT00286442
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 13 |
| Phase 2 | 19 |
| Phase 3 | 18 |
| Phase 4 | 8 |
Top Sponsors
Named interventions
Most-linked intervention names on Diabetes Mellitus records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Diabetes Mellitus trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Diabetes Mellitus page
210 registered trials, 49 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 49 Diabetes Mellitus trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Takeda sponsors the most Diabetes Mellitus trials on record, review their full trial history before evaluating a specific study. See Takeda's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Diabetes Mellitus condition card totals 210 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.