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NCT05234866 · ClinicalTrials.gov registry record
Paradoxical Lucidity in Severe End-Stage Dementia
A clinical trial of Dementia, sponsored by NYU Langone Health.
- Recruiting
- Registry status
- 520
- Enrollment target
- 1
- Study location
NCT05234866 is a study of Dementia that is actively recruiting participants, run by NYU Langone Health. The registered enrollment target is 520 participants, below the 7,720-participant average among 199 other Dementia trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05234866, a study of Dementia, is actively recruiting participants, sponsored by NYU Langone Health.
- RECRUITING
- Registry status
- 520 participants
- Enrollment target
- 1
- Study location
Study Summary
Cognitive decline in dementia is considered irreversible, however episodes of paradoxical lucidity (PL) in severe dementia suggest other mechanisms may be in play. Beyond anecdotal reports of transient PL events occurring in patients predominantly in late-stage dementia and typically lasting anywhere from a few minutes to several hours, little is known about PL. The study team proposes to develop and conduct a mixed methods prospective study of PL during end stage advanced dementia, creating a definition and measurement scale for PL in advanced dementia, and identifying the potential electro cortical biomarkers of PL in advanced dementia. This study will be divided in two phases: Phase I and Phase II. During Phase I, the study team will collect sufficient and necessary data through an online survey and focus groups as well as assess the safety and feasibility of using symptom diaries (also known as daily trackers or journals) and real-time video EEG monitoring (vEEG). After preliminary review of the study procedures, the PI will decide whether to move onto the Phase II. The second phase will aim to expand the study population and refine study methods as well as create a definition and measurement scale for PL in advances dementia.
Conditions Studied
Study Locations (1)
New York
- NYU Langone Health - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 520 participants |
| Start Date | 2022-06-02 |
| Est. Completion | 2026-05-31 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05234866
The ClinicalTrials.gov registry entry for NCT05234866 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 520 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 7,720-participant average among 199 other Dementia trials with a reported enrollment target (93% lower). The listed sponsor is NYU Langone Health, which has 1,164 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Dementia appearing as the primary indexed condition, and to 0 interventions.
NCT05234866 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.
Frequently Asked Questions
What is clinical trial NCT05234866 about?
NCT05234866 is a clinical study titled "Paradoxical Lucidity in Severe End-Stage Dementia". Cognitive decline in dementia is considered irreversible, however episodes of paradoxical lucidity (PL) in severe dementia suggest other mechanisms may be in play. Beyond anecdotal reports of transient PL events occurring in patients predominantly in late-stage dementia and typically lasting anywher...
What is the current status of trial NCT05234866?
This trial is currently recruiting. The enrollment target is 520 participants. The study started on 2022-06-02. Estimated completion is 2026-05-31.
What conditions does trial NCT05234866 study?
This clinical trial studies the following conditions: Dementia.
Who is sponsoring clinical trial NCT05234866?
This trial is sponsored by NYU Langone Health, which has 1,164 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05234866 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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