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NCT05748613 · ClinicalTrials.gov registry record · NA
Anxiety Sensitivity Treatment to Reduce Anxiety in Alzheimer's
A NA study of Anxiety and Alzheimer Disease, sponsored by Florida State University.
- Recruiting
- Registry status
- NA
- Development phase
- 388
- Enrollment target
- 3
- Study locations
NCT05748613: Recruiting NA study of Anxiety and Alzheimer Disease, sponsored by Florida State University.
NCT05748613 is a NA study of Anxiety and Alzheimer Disease that is actively recruiting participants, run by Florida State University. The registered enrollment target is 388 participants, below the 439-participant average among 364 other Anxiety trials with a reported enrollment target (12% lower). The trial reports 3 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05748613, a NA study of Anxiety and Alzheimer Disease, is actively recruiting participants, sponsored by Florida State University.
- RECRUITING
- Registry status
- NA
- Development phase
- 388 participants
- Enrollment target
- 3
- Study locations
Study Summary
The goal of this clinical trial is to test the effectiveness of a computerized anxiety sensitivity treatment (CAST) compared to a health education control (HEC) in older adults with mild cognitive impairment (MCI) or mild Alzheimer's Disease and related dementias (ADRD) and their care partners. The main questions it aims to answer are: 1. Efficacy of CAST in reducing anxiety and related symptoms among those with MCI/mild ADRD 2. Efficacy of CAST in reducing care partner burden among care partners of people living with MCI/mild ADRD 3. Explore treatment mechanisms using a multi-modal assessment battery of anxiety sensitivity and anxiety Participants will complete six in-person visits including a baseline assessment, two intervention sessions, and three follow-up assessments at 1, 3, and 6-months posttreatment. Participants will also complete three weeks of ecological momentary assessments (EMAs) for one week prior to intervention, one week between intervention sessions, and one week after intervention. If there is a comparison group: Researchers will compare CAST to HEC to see if CAST reduces anxiety and related symptoms in older adults with MCI/mild ADRD and care partner burden to a greater degree than HEC.
Primary Outcome
Anxiety sensitivity will be measured using the Anxiety Sensitivity Index-3 (ASI-3). The ASI-3 is an 18-item self report measure with possible scores ranging from 0 to 72. Higher scores indicate higher anxiety sensitivity.
Conditions Studied
Interventions
- BEHAVIORAL Health Education Control
- BEHAVIORAL Computerized Anxiety Sensitivity Treatment
Study Locations (3)
Ohio
- Ohio University - Athens
- The Ohio State University - Columbus
Florida
- Anxiety and Behavioral Health Clinic - Tallahassee
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 388 participants |
| Start Date | 2023-11-02 |
| Est. Completion | 2028-01 |
| Phase | NA |
What NCT05748613 shows while recruiting
NCT05748613 is an interventional study that assigns participants to a tested intervention. The registered 388 participants enrollment target is mid-sized for trials with a published cap, below the 439-participant average among 364 other Anxiety trials with a reported enrollment target (12% lower).
The record links to 4 conditions, with Anxiety appearing as the primary indexed condition, and to 2 interventions - of which Health Education Control is the first listed.
NCT05748613 reports a single indexed study location in Ohio, Florida.
Frequently Asked Questions
What is clinical trial NCT05748613 about?
NCT05748613 is a clinical study titled "Anxiety Sensitivity Treatment to Reduce Anxiety in Alzheimer's". The goal of this clinical trial is to test the effectiveness of a computerized anxiety sensitivity treatment (CAST) compared to a health education control (HEC) in older adults with mild cognitive impairment (MCI) or mild Alzheimer's Disease and related dementias (ADRD) and their care partners. The ...
What is the current status of trial NCT05748613?
This trial is currently recruiting. It is a NA study. The enrollment target is 388 participants. The study started on 2023-11-02. Estimated completion is 2028-01.
What conditions does trial NCT05748613 study?
This clinical trial studies the following conditions: Anxiety, Alzheimer Disease, Mild Cognitive Impairment, Dementia.
What interventions are being tested in trial NCT05748613?
The interventions under investigation include: Health Education Control (BEHAVIORAL), Computerized Anxiety Sensitivity Treatment (BEHAVIORAL).
Who is sponsoring clinical trial NCT05748613?
This trial is sponsored by Florida State University, which has 219 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05748613 being conducted?
This trial has 3 study locations across Florida, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05748613's enrollment target sits among peer trials
388 46th of 364 higher than 319 of 364 other Anxiety trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Anxiety trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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