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NCT05748613 · ClinicalTrials.gov registry record · NA

Anxiety Sensitivity Treatment to Reduce Anxiety in Alzheimer's

A NA study of Anxiety and Alzheimer Disease, sponsored by Florida State University.

Recruiting
Registry status
NA
Development phase
388
Enrollment target
3
Study locations

NCT05748613 is a NA study of Anxiety and Alzheimer Disease that is actively recruiting participants, run by Florida State University. The registered enrollment target is 388 participants, below the 439-participant average among 364 other Anxiety trials with a reported enrollment target (12% lower). The trial reports 3 study locations across 2 states.

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The verdict

NCT05748613, a NA study of Anxiety and Alzheimer Disease, is actively recruiting participants, sponsored by Florida State University.

RECRUITING
Registry status
NA
Development phase
388 participants
Enrollment target
3
Study locations

Study Summary

The goal of this clinical trial is to test the effectiveness of a computerized anxiety sensitivity treatment (CAST) compared to a health education control (HEC) in older adults with mild cognitive impairment (MCI) or mild Alzheimer's Disease and related dementias (ADRD) and their care partners. The main questions it aims to answer are: 1. Efficacy of CAST in reducing anxiety and related symptoms among those with MCI/mild ADRD 2. Efficacy of CAST in reducing care partner burden among care partners of people living with MCI/mild ADRD 3. Explore treatment mechanisms using a multi-modal assessment battery of anxiety sensitivity and anxiety Participants will complete six in-person visits including a baseline assessment, two intervention sessions, and three follow-up assessments at 1, 3, and 6-months posttreatment. Participants will also complete three weeks of ecological momentary assessments (EMAs) for one week prior to intervention, one week between intervention sessions, and one week after intervention. If there is a comparison group: Researchers will compare CAST to HEC to see if CAST reduces anxiety and related symptoms in older adults with MCI/mild ADRD and care partner burden to a greater degree than HEC.

Interventions

  • BEHAVIORAL Health Education Control
  • BEHAVIORAL Computerized Anxiety Sensitivity Treatment

Study Locations (3)

Ohio

  • Ohio University - Athens
  • The Ohio State University - Columbus

Florida

  • Anxiety and Behavioral Health Clinic - Tallahassee

Trial Details

FieldValue
Enrollment Target 388 participants
Start Date 2023-11-02
Est. Completion 2028-01
Phase NA

Sponsor

Florida State University

219 total trials

What the Registry Record Tells You About NCT05748613

The ClinicalTrials.gov registry entry for NCT05748613 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 388 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 439-participant average among 364 other Anxiety trials with a reported enrollment target (12% lower). The listed sponsor is Florida State University, which has 219 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Anxiety appearing as the primary indexed condition, and to 2 interventions - of which Health Education Control is the first listed.

NCT05748613 reports 3 study locations spanning 2 distinct geographic areas - top geographies include Ohio, Florida.

Frequently Asked Questions

What is clinical trial NCT05748613 about?

NCT05748613 is a clinical study titled "Anxiety Sensitivity Treatment to Reduce Anxiety in Alzheimer's". The goal of this clinical trial is to test the effectiveness of a computerized anxiety sensitivity treatment (CAST) compared to a health education control (HEC) in older adults with mild cognitive impairment (MCI) or mild Alzheimer's Disease and related dementias (ADRD) and their care partners. The ...

What is the current status of trial NCT05748613?

This trial is currently recruiting. It is a NA study. The enrollment target is 388 participants. The study started on 2023-11-02. Estimated completion is 2028-01.

What conditions does trial NCT05748613 study?

This clinical trial studies the following conditions: Anxiety, Alzheimer Disease, Mild Cognitive Impairment, Dementia.

What interventions are being tested in trial NCT05748613?

The interventions under investigation include: Health Education Control (BEHAVIORAL), Computerized Anxiety Sensitivity Treatment (BEHAVIORAL).

Who is sponsoring clinical trial NCT05748613?

This trial is sponsored by Florida State University, which has 219 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05748613 being conducted?

This trial has 3 study locations across Florida, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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