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Chronic Obstructive Pulmonary Disease clinical trials
29 of 87 indexed Chronic Obstructive Pulmonary Disease trials are currently recruiting.
87 US clinical trials · 29 currently recruiting
Chronic Obstructive Pulmonary Disease is the subject of 87 registered US clinical trials on ClinicalTrials.gov, 29 of them currently open to new participants. 19 are in Phase 3-4 (later-stage) and 27 in Phase 1-2 (earlier-stage). The most active sponsor is Sanofi, running 6 of these trials.
The research picture
Chronic Obstructive Pulmonary Disease has 87 registered US clinical trials, 29 of them open to new participants right now, about 33% of the total.
- 29
- recruiting participants now
- 33%
- of trials open to enrollment
- 19
- in Phase 3–4 (later-stage)
- 6
- top sponsor: Sanofi
Active & Recent Trials
87 total, page 2 of 2
NVA237 Versus Placebo 12-week Efficacy Study
Novartis Pharmaceuticals
NCT01709864
Efficacy and Safety Study of QVA149 in COPD Patients
Novartis Pharmaceuticals
NCT02487446
Audio Data Collection for Identification and Classification of Coughing
HealthMode
NCT04326309
HIV-related Accelerated Aging of the Airway Epithelium
Weill Medical College of Cornell University
NCT01974219
PT003 MDI Cardiovascular Safety Study
Pearl Therapeutics
NCT01349803
Anxiety and COPD Evaluation
NYU Langone Health
NCT02740465
Active for Life: Chronic Obstructive Pulmonary Disease
University of Michigan
NCT03201198
Remote Physician Care for Home Hospital Patients
Brigham and Women's Hospital
NCT04080570
Video vs. TTG Respiratory Inhaler Technique Assessment and InstructioN (V-TRaIN)
University of Chicago
NCT02611531
Stepped Care vs Center-based Cardiopulmonary Rehabilitation for Older Frail Adults Living in Rural MA
Peter Lindenauer, MD
NCT05562037
Study to Evaluate the Efficacy, Safety and Pharmacokinetics of PT001, PT003, and PT005 Following Chronic Dosing (7 Days) in Patients With Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD)
Pearl Therapeutics
NCT01085045
Mucus Dehydration and Evolution of Chronic Obstructive Pulmonary Disease (COPD) Lung Disease
University of North Carolina, Chapel Hill
NCT00903955
Specialized Community Disease Management to Reduce Substance Use and Hospital Readmissions
Treatment Research Institute
NCT02059005
Vibratory PEP Device and Hospital Length of Stay for Acute Exacerbation of COPD
New York Presbyterian Brooklyn Methodist Hospital
NCT03094806
Vibration Response Imaging in Chronic Obstructive Pulmonary Disease and Asthma
Deep Breeze
NCT00542282
Nebulized Hypertonic Saline for Inpatient Use in COPD
OhioHealth
NCT02266875
A Crossover Study to Determine the 24 Hour Lung Function Profile of Indacaterol in Patients With Moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD)
Novartis Pharmaceuticals
NCT00622635
A 7-Day Cross-over Study of QD (Once Daily) and BID (Twice Daily) TD-4208 in Chronic Obstructive Pulmonary Disease (COPD)
Mylan
NCT02109172
Confirmatory Dose Finding Study of 2 Dosages of CHF 4226 pMDI (Carmoterol) in Patients With COPD
Chiesi Farmaceutici S.p.A.
NCT00640484
COPD Assessment and Management Bundle Versus Usual Care
University of Illinois at Chicago
NCT01833026
Indoor Air Quality and Respiratory Symptoms in Former Smokers
Intermountain Health Care
NCT02956213
A Phase IIb Study of Glycopyrrolate Inhalation Solution Over 1 Week in Subjects With COPD
Verona Pharma
NCT06545500
A Phase II Study to Assess the Pharmacokinetics, Pharmacodynamics, and Safety of Single Inhaled Doses of Ensifentrine-glycopyrrolate Fixed Dose Combination, Ensifentrine, and Glycopyrrolate in Subjects With Chronic Obstructive Pulmonary Disease
Verona Pharma
NCT07132983
Modifying Exercise for the COPD Patient
Angela N Fellner PhD CCRP
NCT02143206
Safety and Efficacy of Adipose Derived Stem Cells for Chronic Obstructive Pulmonary Disease
Kimera Society
NCT02216630
A Fish Oil Supplement to Maintain Body Weight in Patients With Disease-Related Weight Loss
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT00094562
Inhaled Iloprost, Dynamic Hyperinflation, and Oxidative Stress in COPD Patients
Louisiana State University Health Sciences Center in New Orleans
NCT01941225
Mindfulness Based Stress Reduction in COPD
Mayo Clinic
NCT01058499
Efficacy of Inhaling Bronchodilator Medications in Chronic Obstructive Pulmonary Disease
Dartmouth-Hitchcock Medical Center
NCT01391559
Belimumab Treatment of Emphysema Patients With Anti-GRP78 Autoantibodies
University of Alabama at Birmingham
NCT03244059
Effects of the Breathe Technologies Ventilation System in Subjects With Chronic Obstructive Pulmonary Disease
Breathe Technologies
NCT01372462
Mesenchymal Stem Cells in the Treatment of Subjects With Advance Chronic Obstructive Pulmonary Disease (COPD)
Mayo Clinic
NCT04047810
The Effect of STIOLTO™ RESPIMAT® on Fatigue in Chronic Obstructive Pulmonary Disease
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
NCT02845752
Hydrolyzed Casein and Whey Protein Supplementation and the Addition of Leucine to Induce Protein Anabolism in Malnourished COPD Patients
Texas A&M University
NCT01154400
Safety, Tolerability, and Pharmacokinetics of Andecaliximab in Adults With Chronic Obstructive Pulmonary Disease (COPD)
Gilead Sciences
NCT02077465
Uphill Walking as Exercise for COPD Patients
VA Office of Research and Development
NCT04026529
Rural Home Hospital: Proof of Concept
Brigham and Women's Hospital
NCT04531280
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 9 |
| Phase 2 | 18 |
| Phase 3 | 15 |
| Phase 4 | 4 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Chronic Obstructive Pulmonary Disease Trial Landscape
87 indexed Chronic Obstructive Pulmonary Disease studies · 29 recruiting (33%).
Phase mix: 19 late (III/IV) vs 27 early (I/II).
Top sponsor: Sanofi (6 trials), 9 others listed. 37 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Chronic Obstructive Pulmonary Disease?
PlainTrial tracks 87 US clinical trials for Chronic Obstructive Pulmonary Disease, of which 29 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Chronic Obstructive Pulmonary Disease?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.