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NCT01941225 · ClinicalTrials.gov registry record · Phase 2

Inhaled Iloprost, Dynamic Hyperinflation, and Oxidative Stress in COPD Patients

A Phase 2 study of Chronic Obstructive Pulmonary Disease, sponsored by Louisiana State University Health Sciences Center in New Orleans.

Completed
Registry status
Phase 2
Development phase
24
Enrollment target
1
Study location

NCT01941225: Completed Phase 2 study of Chronic Obstructive Pulmonary Disease, sponsored by Louisiana State University Health Sciences Center in New Orleans.

NCT01941225 is a Phase 2 study of Chronic Obstructive Pulmonary Disease that has completed, run by Louisiana State University Health Sciences Center in New Orleans. The registered enrollment target is 24 participants, below the 1,754-participant average among 86 other Chronic Obstructive Pulmonary Disease trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01941225, a Phase 2 study of Chronic Obstructive Pulmonary Disease, has completed, sponsored by Louisiana State University Health Sciences Center in New Orleans.

COMPLETED
Registry status
Phase 2
Development phase
24 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to investigate the role of the pulmonary vasculature in the development and progression of chronic obstructive pulmonary disease (COPD). To accomplish this, an inhaled prostacyclin (iloprost) will be given to patients with COPD and changes in oxidative stress and lung volumes during exercise will be measured.

Primary Outcome

Dynamic hyperinflation will be measured as EELV/TLC ratio (end-expiratory lung volume/total lung capacity ratio) during exercise

Interventions

  • DRUG Placebo
  • DRUG Inhaled iloprost 5.0 mcg

Study Locations (1)

Louisiana

  • LSU Health Sciences Center - New Orleans

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2013-09
Est. Completion 2016-11
Phase Phase 2

What the finished NCT01941225 record still lists

NCT01941225 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 1,754-participant average among 86 other Chronic Obstructive Pulmonary Disease trials with a reported enrollment target (99% lower).

The record links to 1 condition, with Chronic Obstructive Pulmonary Disease appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT01941225 reports a single indexed study location in Louisiana.

Frequently Asked Questions

What is clinical trial NCT01941225 about?

NCT01941225 is a clinical study titled "Inhaled Iloprost, Dynamic Hyperinflation, and Oxidative Stress in COPD Patients". The purpose of this study is to investigate the role of the pulmonary vasculature in the development and progression of chronic obstructive pulmonary disease (COPD). To accomplish this, an inhaled prostacyclin (iloprost) will be given to patients with COPD and changes in oxidative stress and lung vo...

What is the current status of trial NCT01941225?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 24 participants. The study started on 2013-09. Estimated completion is 2016-11.

What conditions does trial NCT01941225 study?

This clinical trial studies the following conditions: Chronic Obstructive Pulmonary Disease.

What interventions are being tested in trial NCT01941225?

The interventions under investigation include: Placebo (DRUG), Inhaled iloprost 5.0 mcg (DRUG).

Who is sponsoring clinical trial NCT01941225?

This trial is sponsored by Louisiana State University Health Sciences Center in New Orleans, which has 45 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01941225 being conducted?

This trial has 1 study location across Louisiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Chronic Obstructive Pulmonary Disease

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT01941225's enrollment target sits among peer trials

24 74th of 86 higher than 13 of 86 other Chronic Obstructive Pulmonary Disease trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Chronic Obstructive Pulmonary Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01941225, the US trial registry maintained by the National Library of Medicine. NCT01941225 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.