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NCT07132983 · ClinicalTrials.gov registry record · Phase 2
A Phase II Study to Assess the Pharmacokinetics, Pharmacodynamics, and Safety of Single Inhaled Doses of Ensifentrine-glycopyrrolate Fixed Dose Combination, Ensifentrine, and Glycopyrrolate in Subjects With Chronic Obstructive Pulmonary Disease
A Phase 2 study of Chronic Obstructive Pulmonary Disease, sponsored by Verona Pharma.
- Completed
- Registry status
- Phase 2
- Development phase
- 33
- Enrollment target
- 4
- Study locations
NCT07132983: Completed Phase 2 study of Chronic Obstructive Pulmonary Disease, sponsored by Verona Pharma.
NCT07132983 is a Phase 2 study of Chronic Obstructive Pulmonary Disease that has completed, run by Verona Pharma. The registered enrollment target is 33 participants, below the 1,754-participant average among 86 other Chronic Obstructive Pulmonary Disease trials with a reported enrollment target (98% lower). The trial reports 4 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07132983, a Phase 2 study of Chronic Obstructive Pulmonary Disease, has completed, sponsored by Verona Pharma.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 33 participants
- Enrollment target
- 4
- Study locations
Study Summary
This study will assess the pharmacokinetics (PK), pharmacodynamics (PD) and safety of ensifentrine and glycopyrrolate fixed dose (FDC) product, the individual components of the FDC (ensifentrine and glycopyrrolate, each in the FDC formulation), ensifentrine 1.5 mg in the FDC formulation and ensifentrine 3 mg in the marketed formulation each administered via a standard jet nebulizer, in adult participants with chronic obstructive pulmonary disease (COPD).
Conditions Studied
Interventions
- DRUG Ensifentrine 3 mg
- DRUG Glycopyrrolate 42.5 mcg
- DRUG Ensifentrine 1.5 mg
- DRUG Ensifentrine 3 mg (marketed formulation)
Study Locations (4)
Florida
- Clinical Research of West Florida Inc - Clearwater - Clearwater
- Clinical Research of West Florida Inc - Tampa - Tampa
Missouri
- Midwest Chest Consultants PC - Saint Charles
South Carolina
- Velocity Clinical Research - Spartanburg - PPDS - Spartanburg
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 33 participants |
| Start Date | 2025-10-06 |
| Est. Completion | 2025-11-28 |
| Phase | Phase 2 |
What the finished NCT07132983 record still lists
NCT07132983 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 33 participants, a relatively small participant target, below the 1,754-participant average among 86 other Chronic Obstructive Pulmonary Disease trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Chronic Obstructive Pulmonary Disease appearing as the primary indexed condition, and to 4 interventions - of which Ensifentrine 3 mg is the first listed.
NCT07132983 reports a single indexed study location in Florida, Missouri, South Carolina.
Frequently Asked Questions
What is clinical trial NCT07132983 about?
NCT07132983 is a clinical study titled "A Phase II Study to Assess the Pharmacokinetics, Pharmacodynamics, and Safety of Single Inhaled Doses of Ensifentrine-glycopyrrolate Fixed Dose Combination, Ensifentrine, and Glycopyrrolate in Subjects With Chronic Obstructive Pulmonary Disease". This study will assess the pharmacokinetics (PK), pharmacodynamics (PD) and safety of ensifentrine and glycopyrrolate fixed dose (FDC) product, the individual components of the FDC (ensifentrine and glycopyrrolate, each in the FDC formulation), ensifentrine 1.5 mg in the FDC formulation and ensifent...
What is the current status of trial NCT07132983?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 33 participants. The study started on 2025-10-06. Estimated completion is 2025-11-28.
What conditions does trial NCT07132983 study?
This clinical trial studies the following conditions: Chronic Obstructive Pulmonary Disease.
What interventions are being tested in trial NCT07132983?
The interventions under investigation include: Ensifentrine 3 mg (DRUG), Glycopyrrolate 42.5 mcg (DRUG), Ensifentrine 1.5 mg (DRUG), Ensifentrine 3 mg (marketed formulation) (DRUG).
Who is sponsoring clinical trial NCT07132983?
This trial is sponsored by Verona Pharma, which has 7 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07132983 being conducted?
This trial has 4 study locations across Florida, Missouri, South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Chronic Obstructive Pulmonary Disease
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07132983's enrollment target sits among peer trials
33 65th of 86 higher than 21 of 86 other Chronic Obstructive Pulmonary Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Chronic Obstructive Pulmonary Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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