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NCT01391559 · ClinicalTrials.gov registry record · NA
Efficacy of Inhaling Bronchodilator Medications in Chronic Obstructive Pulmonary Disease
A NA study of Chronic Obstructive Pulmonary Disease, sponsored by Dartmouth-Hitchcock Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT01391559: Completed NA study of Chronic Obstructive Pulmonary Disease, sponsored by Dartmouth-Hitchcock Medical Center.
NCT01391559 is a NA study of Chronic Obstructive Pulmonary Disease that has completed, run by Dartmouth-Hitchcock Medical Center. The registered enrollment target is 20 participants, below the 1,754-participant average among 86 other Chronic Obstructive Pulmonary Disease trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01391559, a NA study of Chronic Obstructive Pulmonary Disease, has completed, sponsored by Dartmouth-Hitchcock Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
Some patients with Chronic Obstructive Pulmonary Disease (COPD) report that they are uncertain whether they achieve clinical benefit using a dry-powder inhaler (DPI). One possible explanation is that the patient is unable to inhale the dry powder bronchodilator medication into the lower respiratory tract due to a low peak inspiratory flow rate (PIFR). A PIFR \< 60 l/min is considered to be suboptimal flow for a DPI, including the Diskus device. The hypothesis of the study is that the forced expiratory volume in 1 second (FEV1) measured at two hours after inhalation of the study medication will be higher with arformoterol solution (15 mcg) from a nebulizer compared with salmeterol dry powder (50 mcg) inhaled from the Diskus.
Primary Outcome
FEV1
Conditions Studied
Interventions
- DRUG salmeterol
- DRUG arformoterol
Study Locations (1)
New Hampshire
- Dartmouth-Hitchcock Medical Center - Lebanon
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2011-07 |
| Est. Completion | 2012-10 |
| Phase | NA |
What the finished NCT01391559 record still lists
NCT01391559 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 1,754-participant average among 86 other Chronic Obstructive Pulmonary Disease trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Chronic Obstructive Pulmonary Disease appearing as the primary indexed condition, and to 2 interventions - of which salmeterol is the first listed.
NCT01391559 reports a single indexed study location in New Hampshire.
Frequently Asked Questions
What is clinical trial NCT01391559 about?
NCT01391559 is a clinical study titled "Efficacy of Inhaling Bronchodilator Medications in Chronic Obstructive Pulmonary Disease". Some patients with Chronic Obstructive Pulmonary Disease (COPD) report that they are uncertain whether they achieve clinical benefit using a dry-powder inhaler (DPI). One possible explanation is that the patient is unable to inhale the dry powder bronchodilator medication into the lower respiratory ...
What is the current status of trial NCT01391559?
This trial is currently completed. It is a NA study. The enrollment target is 20 participants. The study started on 2011-07. Estimated completion is 2012-10.
What conditions does trial NCT01391559 study?
This clinical trial studies the following conditions: Chronic Obstructive Pulmonary Disease.
What interventions are being tested in trial NCT01391559?
The interventions under investigation include: salmeterol (DRUG), arformoterol (DRUG).
Who is sponsoring clinical trial NCT01391559?
This trial is sponsored by Dartmouth-Hitchcock Medical Center, which has 427 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01391559 being conducted?
This trial has 1 study location across New Hampshire. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Chronic Obstructive Pulmonary Disease
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01391559's enrollment target sits among peer trials
20 75th of 86 higher than 9 of 86 other Chronic Obstructive Pulmonary Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Chronic Obstructive Pulmonary Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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