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End Stage Renal Disease clinical trials
Every US clinical trial registered for End Stage Renal Disease — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
70 US clinical trials · 21 currently recruiting
The research picture
End Stage Renal Disease has 70 registered US clinical trials, 21 of them open to new participants right now — about 30% of the total.
- 21
- recruiting participants now
- 30%
- of trials open to enrollment
- 10
- in Phase 3–4 (later-stage)
- 4
- top sponsor: Vanderbilt University
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Screening for Asymptomatic Coronary Artery Disease in Kidney Transplant Candidates
University of British Columbia
NCT03674307
Dissemination of the Donor Application: Utilizing Social Media to Identify Potential Live Organ Donors
Johns Hopkins University
NCT03803423
SAVE-FistulaS: the SelfWrap-Assisted ArterioVEnous Fistulas Study
VenoStent
NCT06001827
Maturation of Arteriovenous Fistula With Automated Sonography Assessments Trial
Sonavex
NCT06190717
Partners Calciphylaxis Biobank
Massachusetts General Hospital
NCT03032835
Post Market Study for VasQ, an External Support Implant for Arteriovenous Fistula
Laminate Medical Technologies
NCT06516653
CoQ10 and Exercise for Mitochondrial Dysfunction in Advance Kidney Disease
Vanderbilt University Medical Center
NCT05422534
Drug Interaction Potential of Pro-Inflammatory Conditions
Indiana University
NCT07360938
PReSeRVE-HD: Observational Study of the Merit HeRO® Graft and Super HeRO® in Patients on Hemodialysis
Merit Medical Systems
NCT06422871
Shared Decision Making for Kidney Transplant Candidates to Plan for an Organ Offer Decision
Hennepin Healthcare Research Institute
NCT05879302
Impact of Envarsus XR® on Kidney Biopsy Subclinical Rejection and Blood Immunologic Profile
Roberto Gedaly
NCT03321656
Blood Pressure Slopes and Ultrafiltration in Hemodialysis Patients
VA Office of Research and Development
NCT04163614
Safety and Efficacy of Empagliflozin in Hemodialysis
NYU Langone Health
NCT05786443
Light Therapy in End Stage Kidney Disease
University of Pennsylvania
NCT06310161
Intravascular Ultrasound in Patients With End-stage Renal Disease on Dialysis
Boston Medical Center
NCT04399941
Solv Multi-Pass Hemodialysis System In-Center Clinical Study
Medtronic - MITG
NCT07216885
CAPABLE Transplant
Johns Hopkins University
NCT06326905
Tulane Abdominal Transplant Institute (TATI) of Solid Organ Transplantation of HIV-Positive Recipients From HIV-Positive Donors
Tulane University
NCT05159466
Safety & Efficacy of DCR-PHXC in Patients With PH1 and ESRD
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company
NCT04580420
Oral Intradialytic Amino Acid Supplementation to Vitalize End-stage Kidney Disease Patients on Hemodialysis
The University of Texas Health Science Center at San Antonio
NCT05705414
AMSC for Reducing Anastomotic Stenosis in Primary Arteriovenous Anastomoses
Houssam Farres, M.D.
NCT04392206
Genetic Causes of FSGS, Nephrotic Syndrome, or Kidney Failure
Beth Israel Deaconess Medical Center
NCT02194582
Trial to Evaluate and Assess the Effect of Comprehensive Pre-ESKD Education on Home Dialysis Use in Veterans
VA Office of Research and Development
NCT04064086
VIRTUUS Children's Study
Children's Hospital of Philadelphia
NCT03719339
Communication During Hospitalization About Resuscitation Trial
University of Vermont
NCT02984124
Central Blood Pressure and Pulse Wave Velocity in Kidney Transplant Recipients
Children's National Research Institute
NCT04212143
Medtronic Hugo™ Robotic Assisted Surgery (RAS) System in Urologic Surgery (Expand URO)
Medtronic - MITG
NCT05696444
Ferric Citrate in ESRD Pilot Project
Sreedhar Mandayam
NCT03055598
One-month Latent Tuberculosis Treatment for Renal Transplant Candidates
Rutgers, The State University of New Jersey
NCT05411744
Events Before Death
Renal Research Institute
NCT01329055
Inflammation and Nutritional Parameters in Hemodialysis Patients Using Reprocessed Dialyzers
Fresenius Medical Care North America
NCT00440908
Meals MATTER: A Trial of Medically Tailored Meals 2 Weeks vs. 4 Weeks Post Hospital Discharge
Kaiser Permanente
NCT04351880
Dialysis Catheter Comparative Clinical Trial
Tyco Healthcare Group
NCT00526123
Explore Transplant at Home: Improving Low-Income ESRD Patients' Transplant Knowledge
The Methodist Hospital Research Institute
NCT02268682
Palm Tocotrienols in Chronic Hemodialysis (USA)
Wayne State University
NCT02358967
Trial to Evaluate the Sirolimus-Eluting Collagen Implant on AV Fistula Outcomes
Vascular Therapies
NCT02513303
Phosphate Kinetic Modeling
Fresenius Medical Care North America
NCT01003223
A Long-Term Study of Tenapanor Alone or in Combination With Sevelamer in Patients With CKD on Dialysis and HP
Ardelyx
NCT03988920
Protein, Nutrition and Cardiovascular Disease in Stage 5 Chronic Kidney Disease
University of Utah
NCT00566670
Short and Long-Term Effectiveness of Existing Insomnia Therapies for Patients Undergoing Hemodialysis
University of Washington
NCT03534284
Social Networks and Renal Education: Promoting Transplantation
Temple University
NCT03536858
Phase II Randomized Study of the Effects of Growth Hormone on Children and Adolescents on Maintenance Dialysis
National Center for Research Resources (NCRR)
NCT00004340
Percutaneous Less Invasive AV Fistula for Vascular Access in ESRD
Medtronic Endovascular
NCT02363972
Pharmacodynamic Study of AZD1722 in End-stage Renal Disease Patients on Hemodialysis
Ardelyx
NCT01764854
A Study to Evaluate the Safety and Efficacy of Paricalcitol Capsules in Reducing Serum Intact Parathyroid Hormone Levels in End Stage Renal Disease Subjects on Peritoneal Dialysis
Abbott
NCT00646035
C1INH Inhibitor Preoperative and Post Kidney Transplant to Prevent DGF & IRI
Cedars-Sinai Medical Center
NCT02134314
A Study Evaluating the Association of Inflammation With Hemodialysis Access Type
Montefiore Medical Center
NCT01011985
Effects of Hemodialysis on the Sleep/Wake Cycle
Emory University
NCT00460863
Effects of Oral Cholecalciferol (Vitamin D3) on Bone Health, Neuromuscular Function, and Quality of Life in Adults With Chronic Kidney Disease
Creighton University
NCT00511225
A Study to Evaluate the Effect of Renal Function on the Biological Activity of Telavancin
Cumberland Pharmaceuticals
NCT01238796
Use of Immune Globulin Plus Rituximab for Desensitization in Highly HLA Sensitized Patients Awaiting Deceased Donor Kidney Transplantation
Stanley Jordan, MD
NCT01178216
Patiromer Efficacy to Reduce Episodic Hyperkalemia in End Stage Renal Disease Patients
Duke University
NCT03781089
A Comparison of Physical Activity Levels With and Without Feedback Via Fitbit® Flex™ in Hemodialysis Patients
Renal Research Institute
NCT02320513
Inflammation, Proteolysis and IL-1 Beta Receptor Inhibition in Chronic Hemodialysis Patients
Vanderbilt University
NCT00420290
The Effects of Protein Supplementation and Resistance Exercise in Hemodialysis Patients
Vanderbilt University
NCT00179140
Study to Investigate the Pharmacokinetic Comparability of Dosing Triferic AVNU IV by Continuous Infusion and IV Bolus.
Rockwell Medical Technologies
NCT04409132
CellCept/Iron Study: The Iron Ion-Mycophenolate Mofetil Chelation Complex Interaction in Renal Allograft Recipients
University of Michigan
NCT00227045
The Effects of Resistance Exercise and Protein Supplementation in Hemodialysis Patients
Vanderbilt University
NCT00179218
Treatment Modification to Reduce Symptom Burden in Hemodialysis
The Rogosin Institute
NCT01775800
Safety and Dose Finding Study of Xigris in Hemodialysis Patients
George Washington University
NCT01227187
First Evaluation of the Moda-Flx Hemodialysis System™ in Real World Clinical Settings
Diality
NCT06581393
Triferic AVNU Infusion Via Freedom Pump During Hemodialysis
Rockwell Medical Technologies
NCT04689932
Acid-Base Composition With Use of hemoDialysates
Fresenius Medical Care North America
NCT02334267
The Effects of Nutrition Supplementation and Resistance Exercise During Hemodialysis
Vanderbilt University
NCT00179179
Trial of Adoptive Immunotherapy With TRACT to Prevent Rejection in Living Donor Kidney Transplant Recipients
Northwestern University
NCT02145325
A Pilot Study Using Autologous Regulatory T Cell Infusion Zortress (Everolimus) in Renal Transplant Recipients
Roberto Gedaly
NCT03284242
Ertapenem Pharmacokinetics in Patients in Continuous Ambulatory Peritoneal Dialysis
Albany College of Pharmacy and Health Sciences
NCT00939952
Pharmacokinetics and Optimal Dose of Ertapenem in Hemodialysis Patients
Corewell Health East
NCT02159859
Plazomicin Study in ESRD Patients Receiving IHD
Cipla USA
NCT04699656
Eculizumab to Enable Renal Transplantation in Patients With History of Catastrophic Antiphospholipid Antibody Syndrome
Johns Hopkins University
NCT01029587
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 10 |
| Phase 2 | 12 |
| Phase 3 | 4 |
| Phase 4 | 6 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the End Stage Renal Disease Trial Landscape
ClinicalTrials.gov lists 70 US studies indexed under End Stage Renal Disease, and 21 of those are currently open to recruitment — roughly 30% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for End Stage Renal Disease shows 10 late-stage studies (Phase 3 and Phase 4 combined) alongside 22 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for End Stage Renal Disease is led by Vanderbilt University with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 70 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for End Stage Renal Disease?
PlainTrial tracks 70 US clinical trials for End Stage Renal Disease, of which 21 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for End Stage Renal Disease?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.