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Chronic Kidney Diseases clinical trials
46 of 74 indexed Chronic Kidney Diseases trials are currently recruiting.
74 US clinical trials · 46 currently recruiting
Chronic Kidney Diseases is the subject of 74 registered US clinical trials on ClinicalTrials.gov, 46 of them currently open to new participants. 6 are in Phase 3-4 (later-stage) and 15 in Phase 1-2 (earlier-stage). The most active sponsor is Brigham and Women's Hospital, running 6 of these trials.
The research picture
Chronic Kidney Diseases has 74 registered US clinical trials, 46 of them open to new participants right now, about 62% of the total.
- 46
- recruiting participants now
- 62%
- of trials open to enrollment
- 6
- in Phase 3–4 (later-stage)
- 6
- top sponsor: Brigham and Women's Hospital
Active & Recent Trials
74 total, page 1 of 2
Real World Evidence Clinical Utility Study of KidneyIntelX
Renalytix AI
NCT04802395
Home Hospital for Suddenly Ill Adults
Brigham and Women's Hospital
NCT03524222
Kidney Precision Medicine Project
University of Washington
NCT04334707
Care Transitions App for Patients With Multiple Chronic Conditions
Brigham and Women's Hospital
NCT06051058
Proact: A Study of REACT in Subjects With Type 2 Diabetes Mellitus and Chronic Kidney Disease
Prokidney
NCT05099770
SAVE-FistulaS: the SelfWrap-Assisted ArterioVEnous Fistulas Study
VenoStent
NCT06001827
APOL1 Genetic Testing in African Americans
St. Louis University
NCT05656261
American Indian Chronic Renal Insufficiency Cohort Study (AI-CRIC Study)
University of New Mexi
NCT04185844
Improving the Collaborative Health of Minority COVID-19 Survivor and Carepartner Dyads
University of South Carolina
NCT05370014
A Cardiometabolic Health Program Linked With Clinical-Community Support and Mobile Health Telemonitoring to Reduce Health Disparities
Johns Hopkins University
NCT05321368
Pharmacy-led Transitions of Care Intervention to Improve Medication Adherence
University of Tennessee
NCT06374277
Kidney Health: Eat Well, Live Well
University of Texas at Austin
NCT05970341
Mixed Methods Study of Health-Related Social Needs in African American Adults With Chronic Kidney Disease and Type 2 Diabetes Mellitus
Medical College of Wisconsin
NCT05692388
Chronic Kidney Disease-Education (CKD-EDU)
University of Rochester
NCT06410144
Partners Calciphylaxis Biobank
Massachusetts General Hospital
NCT03032835
BLOOM: Biological Legacy of Origin in Mother-Infant Dyads
University of Miami
NCT02000895
Combination of Novel Therapies for CKD Comorbid Depression
Stony Brook University
NCT04422652
SPYRAL GEMINI Pilot Study
Medtronic Vascular
NCT06907147
Ferric Citrate and Chronic Kidney Disease in Children
University of California, Los Angeles
NCT04741646
Sit Less, Interact and Move More (SLIMM) 2 Study
Srinvasan Beddhu
NCT05173714
Mindfulness in Chronic Kidney Disease
Emory University
NCT04099992
Accelerated Age-related Cognitive Decline: Impact of Exercise on Executive Function and Neuroplasticity
Columbia University
NCT05655325
Subclinical Primary Aldosteronism in Diabetes At-Risk for Kidney Disease
Brigham and Women's Hospital
NCT06190158
Interactive Computer-adaptive Chronic Kidney Disease Education Program
University of Chicago
NCT06364358
Inspiratory Muscle Strength Training in Chronic Kidney Disease
University of Colorado, Denver
NCT04911491
Bone in CKD Alkali Response (BICARb Pilot Trial)
Albert Einstein College of Medicine
NCT05918029
Physical Activity in CKD
Children's Hospital of Philadelphia
NCT06624358
Sodium Bicarbonate and Mitochondrial Energetics in Persons With CKD
University of California, Davis
NCT04984226
A Long-Term Follow-Up Study of Participants Exposed to REACT
Prokidney
NCT05918523
A Pilot Study of The CKM JumpStart Tool
University of Washington
NCT05753020
Safety and Tolerability of Vertebral Bone Marrow-derived Mesenchymal Stem Cells (BM-MSC) in Real World Scenarios of Patients With Chronic Kidney Disease (CKD)
Mayo Clinic
NCT06752577
Janus Kinase-STAT Inhibition to Reduce APOL1 Associated Kidney Disease
Duke University
NCT05237388
Effect of Dapagliflozin on Metabolomics and Cardiac Mechanics in Chronic Kidney Disease
Northwestern University
NCT05719714
Effect of Empagliflozin on Podocyte Specific Proteins in African American Veterans With NDKD
Washington D.C. Veterans Affairs Medical Center
NCT06110130
Handgrip Exercise Training and CKD
Emory University
NCT07094906
Oral Iron in Children With Chronic Kidney Disease
Weill Medical College of Cornell University
NCT03991169
Feasibility Trial of Sodium-GLucose coTransporter 2 INhibitors in Pediatric Chronic KIDney DiSease
Ann & Robert H Lurie Children's Hospital of Chicago
NCT06430684
Precision Medicine Approaches to Renal Osteodystrophy
Thomas Nickolas
NCT05880914
Acute Equol Supplementation and Vascular Function in Women With and Without CKD
University of Colorado, Denver
NCT06128278
Enhancing Physical Function in Older Adults With Chronic Kidney Disease
Wake Forest University Health Sciences
NCT06738394
Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) in Chronic Kidney Disease (CKD)
NYU Langone Health
NCT06927024
Concomitant Renal and Urinary Bladder Allograft Transplantation
Mayo Clinic
NCT04626167
Diuretic Tuner Clinical Decision Support
University of Texas Southwestern Medical Center
NCT04759274
Pioglitazone to Reduce Sympathetic Overactivity in CKD Patients
The University of Texas at Arlington
NCT03471117
Anti-Inflammatory Treatment of Uremic Cardiomyopathy With Colchicine
Brigham and Women's Hospital
NCT04500665
Delayed Immunological Tolerance in Patients With Well-functioning Pre-existing HLA-matched Kidney Transplants
University of California, Los Angeles
NCT05525507
Prospective Decision Impact Clinical Utility Trial of KidneyIntelX
Renalytix AI
NCT05198284
Patient Education Video to Reduce OTC NSAIDs
Carilion Clinic
NCT06575205
SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN
Medtronic Vascular
NCT05198674
BRINK (BRain In Kidney Disease) Memory Study 2.0
Anne Murray
NCT04975464
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 7 |
| Phase 2 | 8 |
| Phase 3 | 1 |
| Phase 4 | 5 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Chronic Kidney Diseases Trial Landscape
74 indexed Chronic Kidney Diseases studies · 46 recruiting (62%).
Phase mix: 6 late (III/IV) vs 15 early (I/II).
Top sponsor: Brigham and Women's Hospital (6 trials), 9 others listed. 50 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Chronic Kidney Diseases?
PlainTrial tracks 74 US clinical trials for Chronic Kidney Diseases, of which 46 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Chronic Kidney Diseases?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.