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Anemia clinical trials
Every US clinical trial registered for Anemia — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
74 US clinical trials · 14 currently recruiting
The research picture
Anemia has 74 registered US clinical trials, 14 of them open to new participants right now — about 19% of the total.
- 14
- recruiting participants now
- 19%
- of trials open to enrollment
- 26
- in Phase 3–4 (later-stage)
- 5
- top sponsor: Akebia Therapeutics
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Diamond Blackfan Anemia Registry (DBAR)
Northwell Health
NCT00106015
Effectiveness of Small Phlebotomy Tubes in Reducing Blood Transfusions in Adult Medical Intensive Care Unit and Intermediate Care Unit Patients With Anemia
The University of Texas Health Science Center, Houston
NCT05750654
A New Combination of Evidence-Based Interventions to Improve Primary Care Diagnostic Safety and Efficiency
The University of Texas Health Science Center, Houston
NCT05735314
A Study to Compare Elritercept With Epoetin Alfa to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions
Takeda
NCT07422480
Choline and Iron Deficiency
University of Minnesota
NCT06527391
Kids With Iron Deficiency and Scoliosis
Columbia University
NCT06042699
Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia
Disc Medicine
NCT05320198
129Xe MRI Cardiopulmonary
Bastiaan Driehuys
NCT06038630
Iron Deficiency Anemia (IDA) and the Brain
Children's Hospital Los Angeles
NCT05929729
Luspatercept for Anemia in Lower Risk MDS or Non-proliferative MDS/MPN Neoplasms
H. Lee Moffitt Cancer Center and Research Institute
NCT05732961
Luspatercept for Clonal Cytopenias of Uncertain Significance
Weill Medical College of Cornell University
NCT06788691
177Lu-PSMA-617 in Metastatic Castration Resistant Prostate Cancer (mCRPC) With Bone Marrow Involvement and Cytopenia
M.D. Anderson Cancer Center
NCT07025512
Iron Replacement to Reduce Anemia During Neoadjuvant Chemotherapy
Fox Chase Cancer Center
NCT05800600
Study of DISC-0974-201 in Participants With IBD and Anemia
Disc Medicine
NCT07368972
Effects of Vitamin D and Marine Omega-3 Fatty Acids on Anemia
Brigham and Women's Hospital
NCT01632761
INTERCEPT Blood System for RBCs Study in Regions at Potential Risk for Zika Virus Transfusion-Transmitted Infections
Cerus Corporation
NCT03037164
Ibrutinib and Rituximab Compared With Fludarabine Phosphate, Cyclophosphamide, and Rituximab in Treating Patients With Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
National Cancer Institute (NCI)
NCT02048813
RBC Irradiation, Anemia and Gut Injury
Emory University
NCT02741648
An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Subjects With Myeloproliferative Neoplasm-Associated Myelofibrosis on Concomitant JAK2 Inhibitor Therapy and Who Require Red Blood Cell Transfusions
Celgene
NCT04717414
Lenalidomide With or Without Epoetin Alfa in Treating Patients With Myelodysplastic Syndrome and Anemia
National Cancer Institute (NCI)
NCT00843882
INCB000928 Administered as a Monotherapy or in Combination With Ruxolitinib in Participants With Anemia Due to Myeloproliferative Disorders
Incyte Corporation
NCT04455841
Effects of Pazopanib on Hereditary Hemorrhagic Telangiectasia Related Epistaxis and Anemia (Paz)
Cure HHT
NCT03850964
The Immediate and Long-term Effects of a Novel Marine-based Iron Supplement in Adult Females
Nutraceuticals Research Institute
NCT07199244
Efficacy and Safety Study to Evaluate Vadadustat for the Maintenance Treatment of Anemia in Participants With Dialysis-dependent Chronic Kidney Disease (DD-CKD)
Akebia Therapeutics
NCT02892149
Safety and Efficacy Study of Roxadustat to Treat Anemia in Patients With Chronic Kidney Disease (CKD), Not on Dialysis
AstraZeneca
NCT02174627
Safety of FCM vs. Standard of Care in Treating Iron Deficiency Anemia in Heavy Uterine Bleeding and Post Partum Patients
American Regent
NCT00548860
Transfusion of Prematures Trial
NICHD Neonatal Research Network
NCT01702805
Helen Keller International's Enhanced-Homestead Food Production Program in Burkina Faso
International Food Policy Research Institute
NCT01825226
Study to Evaluate Vadadustat for the Correction of Anemia in Participants With Non-dialysis-dependent Chronic Kidney Disease
Akebia Therapeutics
NCT02648347
Clinical Decision Support for Blood Transfusions to Improve Guideline Adherence
University of Utah
NCT05634005
Safety & Efficacy of Peginesatide for Maintenance Treatment of Anemia in Participants With Chronic Kidney Disease on Hemodialysis
Affymax
NCT00597753
Safety and Tolerability of Intravenous VIT-45 in Patients With Iron Deficiency Anemia
American Regent
NCT00740246
Darbepoetin Alfa With or Without Iron in Treating Anemia Caused By Chemotherapy in Patients With Cancer
Mayo Clinic
NCT00661999
Spot-Check Noninvasive Hemoglobin (SpHb) Clinical Validation
Masimo Corporation
NCT02930850
Study to Compare Safety and Efficacy of HX575 Epoetin Alfa and US-licensed Epoetin Alfa
Sandoz
NCT01693029
PROCRIT Extended Dosing For Maintenance of Hemoglobin in Pre-Dialysis CKD Patients
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
NCT00440466
Caring for Those Who Share: Improving the Health of Wisconsin Blood Donors
Medical College of Wisconsin
NCT00772083
A Study of Mircera in the Treatment of Anemia in Patients With Chronic Kidney Disease Not on Dialysis
Hoffmann-La Roche
NCT00081471
Trial Evaluating the Efficacy and Safety of Oral Vadadustat Once Daily (QD) and Three Times Weekly (TIW) for the Maintenance Treatment of Anemia in Hemodialysis Subjects Converting From Erythropoiesis-Stimulating Agents (ESAs)
Akebia Therapeutics
NCT04313153
Epoetin Alfa With or Without Dexamethasone in Treating Fatigue and Anemia in Patients With Hormone-Refractory Prostate Cancer
Eastern Cooperative Oncology Group
NCT00060398
Epoetin Alfa in Treating Anemia in Patients With Lymphoma, Chronic Lymphocytic Leukemia, or Multiple Myeloma and Anemia Caused By Chemotherapy
Memorial Sloan Kettering Cancer Center
NCT00003341
Frozen Red Blood Cell Transfusions in Trauma Patients
Oregon Health and Science University
NCT01038557
Prevention of Iron Deficiency in Breastfed Infants
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NCT01444261
20-Week Repeat Oral Dose Study of AKB-6548 in Participants With Chronic Kidney Disease and Anemia
Akebia Therapeutics
NCT01906489
Iron Depletion and Replacement in Blood Donors
Memorial Blood Centers, Minnesota
NCT01752413
Conversion Study From Epoetin Alfa to Monthly Peginesatide Injection in Patients With Chronic Kidney Disease on Dialysis
Takeda
NCT01478971
A Study of the Electrocardiogram Effects and Pharmacokinetics of Ferumoxytol in Healthy Men and Women
AMAG Pharmaceuticals
NCT00360425
A Prospective Interventional Study Assessing the Clinical and Operational Effectiveness of Transitioning From Mircera to Daprodustat for the Treatment of Anemia in End Stage Kidney Disease
USRC Kidney Research
NCT05951192
Randomized Trial of Iron Supplementation to Prevent Anemia in Very-low-birth-weight Infants
The University of Texas Health Science Center, Houston
NCT01224236
Spot-Check Noninvasive Hemoglobin (SpHb) Clinical Validation of INVSENSOR00026
Masimo Corporation
NCT03610269
Measurement of Total Hemoglobin by Pulse Oximetry in Neonatal Population
Masimo Corporation
NCT03120702
Erythropoietin (EPO)+/- Filgrastim (G-CSF) vs. Supportive Therapy Alone for Patients With Myelodysplastic Syndromes
Eastern Cooperative Oncology Group
NCT00003138
IV Iron Safety: Evaluation of Iron Species in Healthy Subjects
University of Maryland, Baltimore
NCT02399449
Practical Anemia Bundle for SusTained Blood Recovery
Mayo Clinic
NCT05167734
Long Term Extension Study for the Maintenance Treatment of Anemia Associated With Chronic Kidney Disease (CKD) in Hemodialysis Subjects on Epoetin Alfa / Beta Treatment Versus BAY85-3934
Bayer
NCT02064426
Umbilical Cord Blood Use For Admission Blood Tests of Very Low Birth Weight Preterm Neonates: A Multi-center Randomized Clinical Trial
Capt Alicia Prescott
NCT02103296
BVA-200 vs BVA-100 Validation Study
Daxor Corporation
NCT06227819
Impact of Ferric Citrate vs Ferrous Sulfate on Iron Parameters and Hemoglobin in Individuals With CKD and Iron Deficiency
University of Alabama at Birmingham
NCT02888171
Study of the Efficacy of Two Doses of Ferrlecit in the Treatment of Iron Deficiency in Pediatric Hemodialysis Patients
Watson Pharmaceuticals
NCT00223964
Anemia in Heart Failure With a Preserved Ejection Fraction (HFPEF)
Mathew S. Maurer
NCT00286182
Phase II Study of Lenalidomide and Eltrombopag in Patients With Symptomatic Anemia
Albert Einstein College of Medicine
NCT01772420
Evaluate the Change in Iron, Vitamin D, and C-Reactive Protein Level (CRP) in a 12 to 24 Week Period
Avera McKennan Hospital & University Health Center
NCT01328704
Bone Marrow Transplantation in Treating Patients With Hematologic Cancer
University of Maryland, Baltimore
NCT00003398
Ascertain the Optimal Starting Dose of Mircera Given Subcutaneously for Maintenance Treatment of Anemia in Pediatric Patients With Chronic Kidney Disease on Dialysis or Not Yet on Dialysis.
Hoffmann-La Roche
NCT03552393
A Phase 1 Study of LY2787106 in Cancer and Anemia
Eli Lilly and Company
NCT01340976
Placental Transfusion in Term Infants: A Pilot Study
University of Rhode Island
NCT01924572
Noninvasive Hemoglobin Repeatability and Reproducibility in a Blood Donation Setting
Masimo Corporation
NCT04490863
Milking the Umbilical Cord at Term Cesarean Birth
University of Rhode Island
NCT01630993
Effects Of Darbepoetin On Vascular Repair Mechanisms In Kidney Disease The DARBEPC Study
University of Michigan
NCT00396123
Iron Sucrose in Non-Dialysis Dependent (NDD-CKD) Pediatric Patients
American Regent
NCT00721188
Safety and Efficacy Study for AKB-6548 in Participants With Chronic Kidney Disease and Anemia
Akebia Therapeutics
NCT01235936
Ex Vivo-activated Autologous Lymph Node Lymphocytes in Treating Patients With Chronic Lymphocytic Leukemia
M.D. Anderson Cancer Center
NCT02530515
BioRBC Survival in Adults With Prior Antibody Response to BioRBCs
John A Widness
NCT02077751
Thalidomide and Epoetin Alfa in Treating Anemia in Patients With Myelodysplastic Syndrome
Fallon Clinic
NCT00053001
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 6 |
| Phase 2 | 19 |
| Phase 3 | 20 |
| Phase 4 | 6 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Anemia Trial Landscape
ClinicalTrials.gov lists 74 US studies indexed under Anemia, and 14 of those are currently open to recruitment — roughly 19% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Anemia shows 26 late-stage studies (Phase 3 and Phase 4 combined) alongside 25 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Anemia is led by Akebia Therapeutics with 5 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 74 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Anemia?
PlainTrial tracks 74 US clinical trials for Anemia, of which 14 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Anemia?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.