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NCT04099992 · ClinicalTrials.gov registry record · NA
Mindfulness in Chronic Kidney Disease
A NA study of Chronic Kidney Diseases, sponsored by Emory University.
- Recruiting
- Registry status
- NA
- Development phase
- 150
- Enrollment target
- 1
- Study location
NCT04099992: Recruiting NA study of Chronic Kidney Diseases, sponsored by Emory University.
NCT04099992 is a NA study of Chronic Kidney Diseases that is actively recruiting participants, run by Emory University. The registered enrollment target is 150 participants, below the 443-participant average among 73 other Chronic Kidney Diseases trials with a reported enrollment target (66% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04099992, a NA study of Chronic Kidney Diseases, is actively recruiting participants, sponsored by Emory University.
- RECRUITING
- Registry status
- NA
- Development phase
- 150 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will test whether mindfulness meditation (MM) improves sympathetic function in chronic kidney disease (CKD) and whether transcutaneous vagus nerve stimulation (tVNS) optimizes the sympatho-inhibitory effects of mindfulness meditation (MM) and restores autonomic balance in CKD patients.
Primary Outcome
Multiunit postganglionic sympathetic nerve activity is recorded from a tungsten microelectrode inserted into the peroneal nerve with a reference microelectrode inserted in close proximity. Efferent nerve signals are amplified, filtered, rectified and integrated (time constant 0.1 s) to obtain a mean voltage display of MSNA. MSNA bursts are automatically detected using the following criteria: burst-to-noise ratio of 3:1 within a 0.5-s search window, with an average latency of 1.2-1.3 s in burst o
Conditions Studied
Interventions
- BEHAVIORAL Mindfulness-based stress reduction (MBSR)
- BEHAVIORAL Health enhancement program (HEP)
- DEVICE Transcutaneous Vagus Nerve Stimulation (tVNS)
- DEVICE Sham-transcutaneous Vagus Nerve Stimulation (tVNS)
Study Locations (1)
Georgia
- Atlanta VA Medical Center - Atlanta
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2019-09-20 |
| Est. Completion | 2026-09 |
| Phase | NA |
What NCT04099992 shows while recruiting
NCT04099992 is an interventional study that assigns participants to a tested intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, below the 443-participant average among 73 other Chronic Kidney Diseases trials with a reported enrollment target (66% lower).
The record links to 1 condition, with Chronic Kidney Diseases appearing as the primary indexed condition, and to 4 interventions - of which Mindfulness-based stress reduction (MBSR) is the first listed.
NCT04099992 reports a single indexed study location in Georgia.
Frequently Asked Questions
What is clinical trial NCT04099992 about?
NCT04099992 is a clinical study titled "Mindfulness in Chronic Kidney Disease". This study will test whether mindfulness meditation (MM) improves sympathetic function in chronic kidney disease (CKD) and whether transcutaneous vagus nerve stimulation (tVNS) optimizes the sympatho-inhibitory effects of mindfulness meditation (MM) and restores autonomic balance in CKD patients.
What is the current status of trial NCT04099992?
This trial is currently recruiting. It is a NA study. The enrollment target is 150 participants. The study started on 2019-09-20. Estimated completion is 2026-09.
What conditions does trial NCT04099992 study?
This clinical trial studies the following conditions: Chronic Kidney Diseases.
What interventions are being tested in trial NCT04099992?
The interventions under investigation include: Mindfulness-based stress reduction (MBSR) (BEHAVIORAL), Health enhancement program (HEP) (BEHAVIORAL), Transcutaneous Vagus Nerve Stimulation (tVNS) (DEVICE), Sham-transcutaneous Vagus Nerve Stimulation (tVNS) (DEVICE).
Who is sponsoring clinical trial NCT04099992?
This trial is sponsored by Emory University, which has 1,208 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04099992 being conducted?
This trial has 1 study location across Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Chronic Kidney Diseases
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04099992's enrollment target sits among peer trials
150 33rd of 73 higher than 41 of 73 other Chronic Kidney Diseases trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Chronic Kidney Diseases trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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