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NCT04984226 · ClinicalTrials.gov registry record · Phase 2
Sodium Bicarbonate and Mitochondrial Energetics in Persons With CKD
A Phase 2 study of Diabetes and Insulin Resistance, sponsored by University of California, Davis.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 80
- Enrollment target
- 2
- Study locations
NCT04984226 is a Phase 2 study of Diabetes and Insulin Resistance that is actively recruiting participants, run by University of California, Davis. The registered enrollment target is 80 participants, below the 3,028-participant average among 338 other Diabetes trials with a reported enrollment target (97% lower). The trial reports 2 study locations across 2 states.
The verdict
NCT04984226, a Phase 2 study of Diabetes and Insulin Resistance, is actively recruiting participants, sponsored by University of California, Davis.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 80 participants
- Enrollment target
- 2
- Study locations
Study Summary
Skeletal muscle metabolic health is critical for mobility and an underrecognized target of metabolic acidosis in chronic kidney disease. Impaired muscle mitochondrial metabolism underlies poor physical endurance increasing the risk of mobility disability. The proposed project will use precise in vivo tools to study the pathophysiology of poor physical endurance in a clinical trial treating metabolic acidosis among persons living with chronic kidney disease.
Conditions Studied
Interventions
- DRUG placebo
- DRUG Sodium bicarbonate
Study Locations (2)
California
- University of California Davis Health - Sacramento
Tennessee
- Vanderbilt University Medical Center - Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2023-09-08 |
| Est. Completion | 2026-07-30 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04984226
The ClinicalTrials.gov registry entry for NCT04984226 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 80 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 3,028-participant average among 338 other Diabetes trials with a reported enrollment target (97% lower). The listed sponsor is University of California, Davis, which has 657 total studies on file at ClinicalTrials.gov.
The record links to 7 conditions, with Diabetes appearing as the primary indexed condition, and to 2 interventions - of which placebo is the first listed.
NCT04984226 reports 2 study locations spanning 2 distinct geographic areas - top geographies include California, Tennessee.
Frequently Asked Questions
What is clinical trial NCT04984226 about?
NCT04984226 is a clinical study titled "Sodium Bicarbonate and Mitochondrial Energetics in Persons With CKD". Skeletal muscle metabolic health is critical for mobility and an underrecognized target of metabolic acidosis in chronic kidney disease. Impaired muscle mitochondrial metabolism underlies poor physical endurance increasing the risk of mobility disability. The proposed project will use precise in viv...
What is the current status of trial NCT04984226?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 80 participants. The study started on 2023-09-08. Estimated completion is 2026-07-30.
What conditions does trial NCT04984226 study?
This clinical trial studies the following conditions: Diabetes, Insulin Resistance, Fatigue, Chronic Kidney Diseases, Metabolic Acidosis.
What interventions are being tested in trial NCT04984226?
The interventions under investigation include: placebo (DRUG), Sodium bicarbonate (DRUG).
Who is sponsoring clinical trial NCT04984226?
This trial is sponsored by University of California, Davis, which has 657 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04984226 being conducted?
This trial has 2 study locations across California, Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.