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Cardiac Surgery
Open-data reference.
20 US clinical trials · 6 currently recruiting
Active & Recent Trials
Nitric Oxide for Reduced Intensive Support in Cardiac Surgery With Cardiopulmonary Bypass
Xijing Hospital
NCT06702553
Transfusion Requirements in Younger Patients Undergoing Cardiac Surgery
Unity Health Toronto
NCT04754022
Cardiopulmonary Bypass Induced Red Blood Cell Lysis
University of Maryland, Baltimore
NCT05189262
Assessing the Burden of Perioperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery
Brigham and Women's Hospital
NCT04880265
Oral Methadone in Cardiac Surgery
Mayo Clinic
NCT07221617
Pilot Study Evaluating the Advantages of Sucrosomial® Iron Post-operative Supplementation vs Standard of Care After Cardiac Surgery
Englewood Hospital and Medical Center
NCT06970925
Low Tidal Volume Ventilation With Hyperoxia Avoidance During Cardiopulmonary Bypass (The FOCUS Trial)
The Cleveland Clinic
NCT04978636
ESP/PIF for Sternotomy
Icahn School of Medicine at Mount Sinai
NCT04985500
Ketamine and Kidney Injury in Cardiac Surgery
Mayo Clinic
NCT05268562
A Randomized Clinical Trial to Measure Efficacy of Music on Cardiac Surgery Patients
Massachusetts General Hospital
NCT04551469
Safety and Efficacy of an Antibiotic Implant in Cardiac Surgical Subjects at Higher Risk for Sternal Wound Infection
Innocoll
NCT00600483
Impact of Blood Storage Duration on Physiologic Measures
Duke University
NCT01274390
Remote Ischemic Preconditioning in Cardiac Surgery Trial
McMaster University
NCT01071265
Management of Antiplatelet Regimen During Surgical Procedures
Baylor Research Institute
NCT03981835
Effects of a Hybrid Model of Cardiac Rehabilitation on Patient Outcomes
Good Shepherd Integrated Healthcare Systems
NCT06030115
Acute Normovolemic Hemodilution in Complex Cardiac Surgery
University of California, Los Angeles
NCT05049590
Comparison Endotracheal Cardiac Output Monitor (ECOM) to a Standard Device in Measuring Heart Blood Volume
University of California, Los Angeles
NCT00883857
CNAP™ Monitor Study
Nationwide Children's Hospital
NCT01356082
Impact of Ascorbic Acid on Post-Cardiothoracic Surgery Inflammation
Hartford Hospital
NCT00519337
RECOVER I Impella RECOVER LP/LD 5.0 Support System Safety and Feasibility Study
Abiomed
NCT00596726
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 2 |
| Phase 2 | 1 |
| Phase 3 | 3 |
| Phase 4 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Cardiac Surgery Trial Landscape
ClinicalTrials.gov lists 20 US studies indexed under Cardiac Surgery, and 6 of those are currently open to recruitment — roughly 30% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Cardiac Surgery shows 6 late-stage studies (Phase 3 and Phase 4 combined) alongside 3 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Cardiac Surgery is led by University of California, Los Angeles with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 20 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Cardiac Surgery?
PlainTrial tracks 20 US clinical trials for Cardiac Surgery, of which 6 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Cardiac Surgery?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.