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NCT04754022 · ClinicalTrials.gov registry record · NA
Transfusion Requirements in Younger Patients Undergoing Cardiac Surgery
A NA study of Cardiac Surgery and Post Operative, sponsored by Unity Health Toronto.
- Recruiting
- Registry status
- NA
- Development phase
- 1,440
- Enrollment target
- 20
- Study locations
NCT04754022: Recruiting NA study of Cardiac Surgery and Post Operative, sponsored by Unity Health Toronto.
NCT04754022 is a NA study of Cardiac Surgery and Post Operative that is actively recruiting participants, run by Unity Health Toronto. The registered enrollment target is 1,440 participants, above the 670-participant average among 19 other Cardiac Surgery trials with a reported enrollment target (115% higher). The trial reports 20 study locations across 14 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04754022, a NA study of Cardiac Surgery and Post Operative, is actively recruiting participants, sponsored by Unity Health Toronto.
- RECRUITING
- Registry status
- NA
- Development phase
- 1,440 participants
- Enrollment target
- 20
- Study locations
Study Summary
TRICS-IV is an international, multi-centre, open-label randomized controlled trial of two commonly used transfusion strategies in moderate to high risk patients who are 65 years of age or younger undergoing cardiac surgery on cardiopulmonary bypass, using a superiority trial design.
Primary Outcome
Any of all-cause mortality, myocardial infarction, new onset renal failure requiring dialysis, or new focal neurological deficit (stroke).
Conditions Studied
Interventions
- OTHER Restrictive Transfusion Strategy
- OTHER Liberal transfusion strategy
Study Locations (20)
New South Wales
- Royal Prince Alfred hospital - Camperdown
- Prince of Wales Hospital - Randwick
- Westmead Hospital - Westmead
Victoria
- Monash Health - Clayton
- St Vincent's Hospital Melbourne - Fitzroy
- Austin Health - Heidelberg
Other
- Royal Melbourne Hospital - Melbourne
- Alfred Hospital - Prahran
British Columbia
- Interior Health Kelowna General Hospital - Kelowna
- Vancouver General Hospital - Vancouver
Maine
- Maine Medical Center - Portland
New Jersey
- The Cooper Health System - Camden
New York
- Columbia University - New York
Pennsylvania
- Thomas Jefferson University - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,440 participants |
| Start Date | 2021-11-01 |
| Est. Completion | 2026-06 |
| Phase | NA |
What NCT04754022 shows while recruiting
NCT04754022 is an interventional study that assigns participants to a tested intervention. Its 1,440 participants enrollment target places it among the larger protocols in the corpus, above the 670-participant average among 19 other Cardiac Surgery trials with a reported enrollment target (115% higher).
The record links to 4 conditions, with Cardiac Surgery appearing as the primary indexed condition, and to 2 interventions - of which Restrictive Transfusion Strategy is the first listed.
NCT04754022 names 20 study sites across 14 states, led by New South Wales, Victoria, Other.
Frequently Asked Questions
What is clinical trial NCT04754022 about?
NCT04754022 is a clinical study titled "Transfusion Requirements in Younger Patients Undergoing Cardiac Surgery". TRICS-IV is an international, multi-centre, open-label randomized controlled trial of two commonly used transfusion strategies in moderate to high risk patients who are 65 years of age or younger undergoing cardiac surgery on cardiopulmonary bypass, using a superiority trial design.
What is the current status of trial NCT04754022?
This trial is currently recruiting. It is a NA study. The enrollment target is 1,440 participants. The study started on 2021-11-01. Estimated completion is 2026-06.
What conditions does trial NCT04754022 study?
This clinical trial studies the following conditions: Cardiac Surgery, Post Operative, Heart, Disorder.
What interventions are being tested in trial NCT04754022?
The interventions under investigation include: Restrictive Transfusion Strategy (OTHER), Liberal transfusion strategy (OTHER).
Who is sponsoring clinical trial NCT04754022?
This trial is sponsored by Unity Health Toronto, which has 12 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04754022 being conducted?
This trial has 20 study locations across Maine, New Jersey, New York, Pennsylvania, Adelaide. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cardiac Surgery
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04754022's enrollment target sits among peer trials
1,440 4th of 19 higher than 16 of 19 other Cardiac Surgery trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cardiac Surgery trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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