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NCT05189262 · ClinicalTrials.gov registry record
Cardiopulmonary Bypass Induced Red Blood Cell Lysis
A clinical trial of Cardiac Surgery and Cardiopulmonary Bypass, sponsored by University of Maryland, Baltimore.
- Recruiting
- Registry status
- 150
- Enrollment target
- 1
- Study location
NCT05189262 is a study of Cardiac Surgery and Cardiopulmonary Bypass that is actively recruiting participants, run by University of Maryland, Baltimore. The registered enrollment target is 150 participants, below the 738-participant average among 19 other Cardiac Surgery trials with a reported enrollment target (80% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05189262, a study of Cardiac Surgery and Cardiopulmonary Bypass, is actively recruiting participants, sponsored by University of Maryland, Baltimore.
- RECRUITING
- Registry status
- 150 participants
- Enrollment target
- 1
- Study location
Study Summary
Studying the dynamics of red blood cell lysis, pfH, protective proteins and organ injury, limits will be set for safe levels of pfH following the use of CPB. These results will be compared to existing laboratory-based methods for determining red blood cell damage to predict CPB assist device safety. Further, results from the studies described in this proposal will help develop therapeutic strategies to benefit patients by early detection of pfH and clearance protein levels that occur during CPB.
Conditions Studied
Interventions
- OTHER Blood and urine collection
Study Locations (1)
Maryland
- Center for Blood Oxygen Transport and Hemostasis - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2022-03-22 |
| Est. Completion | 2027-12-01 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05189262
The ClinicalTrials.gov registry entry for NCT05189262 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 150 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 738-participant average among 19 other Cardiac Surgery trials with a reported enrollment target (80% lower). The listed sponsor is University of Maryland, Baltimore, which has 560 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Cardiac Surgery appearing as the primary indexed condition, and to 1 intervention - of which Blood and urine collection is the first listed.
NCT05189262 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.
Frequently Asked Questions
What is clinical trial NCT05189262 about?
NCT05189262 is a clinical study titled "Cardiopulmonary Bypass Induced Red Blood Cell Lysis". Studying the dynamics of red blood cell lysis, pfH, protective proteins and organ injury, limits will be set for safe levels of pfH following the use of CPB. These results will be compared to existing laboratory-based methods for determining red blood cell damage to predict CPB assist device safety....
What is the current status of trial NCT05189262?
This trial is currently recruiting. The enrollment target is 150 participants. The study started on 2022-03-22. Estimated completion is 2027-12-01.
What conditions does trial NCT05189262 study?
This clinical trial studies the following conditions: Cardiac Surgery, Cardiopulmonary Bypass, Kidney Injury, Acute.
What interventions are being tested in trial NCT05189262?
The interventions under investigation include: Blood and urine collection (OTHER).
Who is sponsoring clinical trial NCT05189262?
This trial is sponsored by University of Maryland, Baltimore, which has 560 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05189262 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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