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ClinicalTrials.gov 5 recruiting now official registry

Acute Myocardial Infarction clinical trials

5 of 20 indexed Acute Myocardial Infarction trials are currently recruiting.

20 US clinical trials · 5 currently recruiting

Acute Myocardial Infarction is the subject of 20 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Hennepin Healthcare Research Institute, running 2 of these trials.

The research picture

Acute Myocardial Infarction has 20 registered US clinical trials, 5 of them open to new participants right now, about 25% of the total.

5
recruiting participants now
25%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
2
top sponsor: Hennepin Healthcare Research Institute
Phase 11Phase 23Phase 41

Active & Recent Trials

20 total, page 1 of 1

RECRUITING NA 5,100 participants

Physiology-guided vs Angiography-guided Non-culprit Lesion Complete Revascularization for Acute MI & Multivessel Disease

Population Health Research Institute

NCT05701358

RECRUITING 3,784 participants

Abbott Vascular Medical Device Registry

Abbott Medical Devices

NCT04573660

RECRUITING 500 participants

Multi-center Collaborative to Enhance Quality and Outcomes in the Management of Cardiogenic Shock

Stavros G Drakos

NCT05185492

RECRUITING NA 434 participants

Delivery SSO2 Therapy for 60 Min in Anterior MI Patients With PCI ≤ 6 Hours of Symptoms Onset Compared to Standard.

TherOx

NCT04743245

RECRUITING NA 200 participants

Arrhythmia Detection After MI

Samir Saba

NCT05073419

ACTIVE NOT RECRUITING 2,000 participants

COmparisoN of High-sensitivity Cardiac TRoponin I and T ASsays Trial

Hennepin Healthcare Research Institute

NCT03214029

ACTIVE NOT RECRUITING 1,500 participants

MERITnI - Mindray-hs-cTnI Assay: Analytical and Clinical Evaluation for the Diagnosis and RIsk AssessmenT of Myocardial InfarctIon.

Hennepin Healthcare Research Institute

NCT05853042

ACTIVE NOT RECRUITING 664 participants

Molecular and Morphologic Characterization of Circulating Endothelial Cells

Scripps Translational Science Institute

NCT01005485

COMPLETED 12,000 participants

Acute Clinical Outcomes of Hemorrhagic Myocardial Infarction

Indiana University

NCT06110351

COMPLETED 6,180 participants

Antiplatelets and Intramyocardial Hemorrhage in STEMI: Incidence and Outcomes

Rohan Dharmakumar

NCT06851325

COMPLETED Phase 2 1,601 participants

Study to Gather Information About the Proper Dosing and Safety of the Oral FXIa Inhibitor BAY 2433334 in Patients Following an Acute Heart Attack

Bayer

NCT04304534

COMPLETED NA 447 participants

Enhancing Cardiac Rehabilitation Through Behavioral Nudges

Denver Health and Hospital Authority

NCT03834155

COMPLETED 406 participants

National Cardiogenic Shock Initiative

Henry Ford Health System

NCT03677180

COMPLETED Phase 4 390 participants

Pre-hospital Administration of Thrombolytic Therapy With Urgent Culprit Artery Revascularization

The University of Texas Health Science Center, Houston

NCT00178620

COMPLETED 262 participants

Coronary Collaterals and Post-reperfusion Intramyocardial Hemorrhage

Indiana University

NCT05898425

COMPLETED NA 97 participants

Specialized Community Disease Management to Reduce Substance Use and Hospital Readmissions

Treatment Research Institute

NCT02059005

COMPLETED Phase 2 59 participants

Nesiritide Therapy to Preserve Function of the Left Ventricle After Myocardial Infarction

Mayo Clinic

NCT00573144

COMPLETED 59 participants

ClearWay Rx Readmission Registry

Cardiovascular Institute of the South Clinical Research Corporation

NCT01673893

COMPLETED Phase 1 41 participants

Bone Marrow Stem Cell Infusion Following a Heart Attack

Minneapolis Heart Institute Foundation

NCT00268307

COMPLETED Phase 2 40 participants

A Study of INO-1001, an Intravenous PARP (Poly [ADP Ribose] Polymerase) Inhibitor in Acute Heart Attack Patients Undergoing Primary Percutaneous Coronary Intervention

Inotek Pharmaceuticals Corporation

NCT00271765

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 3
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Acute Myocardial Infarction Trial Landscape

20 indexed Acute Myocardial Infarction studies · 5 recruiting (25%).

Phase mix: 1 late (III/IV) vs 4 early (I/II).

Top sponsor: Hennepin Healthcare Research Institute (2 trials), 9 others listed. 20 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Acute Myocardial Infarction?

PlainTrial tracks 20 US clinical trials for Acute Myocardial Infarction, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Acute Myocardial Infarction?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.