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ClinicalTrials.gov 5 recruiting now early-phase tilt

Acute Myocardial Infarction: early-phase trial registry

5 of 20 indexed Acute Myocardial Infarction trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #848 of 28,707 conditions by registered trial count.

20 US clinical trials · 5 currently recruiting · #848 of 28,707 conditions by registered trial count

Acute Myocardial Infarction: 20 US clinical trials tracked, 5 recruiting.

Acute Myocardial Infarction is the subject of 20 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Hennepin Healthcare Research Institute, running 2 of these trials.

Enrollment posture brief

Registry condition acute-myocardial-infarction

OPEN 5 | RECR 25% | LATE 1 | EARLY 4 | RANK #848 | SPON 2

Nearest open-share peer: Abdominal Cancer (25% recruiting · 8 trials)

Analgesia60%Advanced or Metastatic Solid55%ALS50%Abdominal Pain25%Acute Myocardial Infarct (th…25%
Open-enrollment share among volume-matched conditions near Acute Myocardial Infarction

Acute Myocardial Infarction lists 5 open slots (25% of 20 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Acute Myocardial Infarction on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Acute Myocardial Infarction is recruiting below its size-band peers.

    5 of 20 indexed trials (25%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Acute Myocardial Infarction trials is spread across many organizations.

    Hennepin Healthcare Research Institute accounts for 2 of 20 trials (10%). 18 distinct sponsors appear on at least one study for this condition label.

  3. Typical Acute Myocardial Infarction enrolment sits around 447 participants.

    Median target enrolment is 447 among the 20 trials that report a genuine target (sentinel values excluded). 5 of those (25%) plan for fewer than 100 participants.

  4. Acute Myocardial Infarction splits between interventional and observational designs.

    10 interventional and 10 observational studies make up this index (50% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 23Phase 41

Open and recent trials

20 total, page 1 of 1

RECRUITING NA 5,100 participants

Physiology-guided vs Angiography-guided Non-culprit Lesion Complete Revascularization for Acute MI & Multivessel Disease

Population Health Research Institute

NCT05701358

RECRUITING 3,784 participants

Abbott Vascular Medical Device Registry

Abbott Medical Devices

NCT04573660

RECRUITING 500 participants

Multi-center Collaborative to Enhance Quality and Outcomes in the Management of Cardiogenic Shock

Stavros G Drakos

NCT05185492

RECRUITING NA 434 participants

Delivery SSO2 Therapy for 60 Min in Anterior MI Patients With PCI ≤ 6 Hours of Symptoms Onset Compared to Standard.

TherOx

NCT04743245

RECRUITING NA 200 participants

Arrhythmia Detection After MI

Samir Saba

NCT05073419

ACTIVE NOT RECRUITING 2,000 participants

COmparisoN of High-sensitivity Cardiac TRoponin I and T ASsays Trial

Hennepin Healthcare Research Institute

NCT03214029

ACTIVE NOT RECRUITING 1,500 participants

MERITnI - Mindray-hs-cTnI Assay: Analytical and Clinical Evaluation for the Diagnosis and RIsk AssessmenT of Myocardial InfarctIon.

Hennepin Healthcare Research Institute

NCT05853042

ACTIVE NOT RECRUITING 664 participants

Molecular and Morphologic Characterization of Circulating Endothelial Cells

Scripps Translational Science Institute

NCT01005485

COMPLETED 12,000 participants

Acute Clinical Outcomes of Hemorrhagic Myocardial Infarction

Indiana University

NCT06110351

COMPLETED 6,180 participants

Antiplatelets and Intramyocardial Hemorrhage in STEMI: Incidence and Outcomes

Rohan Dharmakumar

NCT06851325

COMPLETED Phase 2 1,601 participants

Study to Gather Information About the Proper Dosing and Safety of the Oral FXIa Inhibitor BAY 2433334 in Patients Following an Acute Heart Attack

Bayer

NCT04304534

COMPLETED NA 447 participants

Enhancing Cardiac Rehabilitation Through Behavioral Nudges

Denver Health and Hospital Authority

NCT03834155

COMPLETED 406 participants

National Cardiogenic Shock Initiative

Henry Ford Health System

NCT03677180

COMPLETED Phase 4 390 participants

Pre-hospital Administration of Thrombolytic Therapy With Urgent Culprit Artery Revascularization

The University of Texas Health Science Center, Houston

NCT00178620

COMPLETED 262 participants

Coronary Collaterals and Post-reperfusion Intramyocardial Hemorrhage

Indiana University

NCT05898425

COMPLETED NA 97 participants

Specialized Community Disease Management to Reduce Substance Use and Hospital Readmissions

Treatment Research Institute

NCT02059005

COMPLETED Phase 2 59 participants

Nesiritide Therapy to Preserve Function of the Left Ventricle After Myocardial Infarction

Mayo Clinic

NCT00573144

COMPLETED 59 participants

ClearWay Rx Readmission Registry

Cardiovascular Institute of the South Clinical Research Corporation

NCT01673893

COMPLETED Phase 1 41 participants

Bone Marrow Stem Cell Infusion Following a Heart Attack

Minneapolis Heart Institute Foundation

NCT00268307

COMPLETED Phase 2 40 participants

A Study of INO-1001, an Intravenous PARP (Poly [ADP Ribose] Polymerase) Inhibitor in Acute Heart Attack Patients Undergoing Primary Percutaneous Coronary Intervention

Inotek Pharmaceuticals Corporation

NCT00271765

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 3
Phase 4 1

Named interventions

Most-linked intervention names on Acute Myocardial Infarction records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Choice of Hospital or home-based CR + Movn Application + Nudge Other
1 trials
Hospital-based CR + Movn Application + Nudge Other
1 trials
Choice of Hospital or home-based CR + Movn Application Other
1 trials
Hospital-based CR + Movn Application Other
1 trials
Autologous, Unfractionated Bone Marrow Mononuclear Cells Drug
1 trials
ClearWay™ Rx catheter Device
1 trials
INO-1001 Drug
1 trials
BAY2433334 matching placebo Other
1 trials

US sites by state

Facility locations filed on Acute Myocardial Infarction trials. A trial with sites in several states counts in each.

Minnesota 7 trials
Indiana 5 trials
Florida 5 trials
California 5 trials
Pennsylvania 4 trials
Virginia 3 trials
Ohio 3 trials
New Jersey 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Acute Myocardial Infarction page

20 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Acute Myocardial Infarction condition card totals 20 registered trials; most-linked intervention Choice of Hospital or home-based CR + Movn Application + Nudge; top US site state Minnesota. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.