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NCT01071265 · ClinicalTrials.gov registry record · NA
Remote Ischemic Preconditioning in Cardiac Surgery Trial
A NA study of Cardiac Surgery, sponsored by McMaster University.
- Completed
- Registry status
- NA
- Development phase
- 250
- Enrollment target
- 7
- Study locations
NCT01071265: Completed NA study of Cardiac Surgery, sponsored by McMaster University.
NCT01071265 is a NA study of Cardiac Surgery that has completed, run by McMaster University. The registered enrollment target is 250 participants, below the 732-participant average among 19 other Cardiac Surgery trials with a reported enrollment target (66% lower). The trial reports 7 study locations across 5 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01071265, a NA study of Cardiac Surgery, has completed, sponsored by McMaster University.
- COMPLETED
- Registry status
- NA
- Development phase
- 250 participants
- Enrollment target
- 7
- Study locations
Study Summary
Main Research Questions: 1. Is a large trial of patients undergoing heart surgery comparing a simple procedure of temporarily stopping blood flow to the leg with a blood pressure cuff (called remote ischemic preconditioning) to a sham procedure possible? 2. Does the remote ischemic preconditioning procedure before heart surgery help protect the heart and kidneys? What is Being Studied: A simple procedure known as remote ischemic preconditioning. The procedure is performed by inflating a pressurized cuff the thigh to temporarily stop blood flow to the arm or leg. This procedure causes the body to have a stress response that, at the cellular level, may protect major organs like the heart and kidney from the damage caused to them by the much larger stress of cardiac surgery. Reducing this damage may improve patient's recovery after surgery and help them live longer. Why is this study important?: This research is important because up to 1 in every 20 patients that undergo heart surgery die before even leaving hospital. Preventing heart and kidney damage at the time of surgery with remote ischemic preconditioning may reduce patient deaths.
Primary Outcome
Peak CK-MB within 24 hours after surgery
Conditions Studied
Interventions
- PROCEDURE Sham
- PROCEDURE Remote Ischemic Preconditioning
Study Locations (7)
Ontario
- McMaster University - Hamilton
- Lawson Health Research Institute - London
- Sunnybrook Hospital - Toronto
Maine
- Maine Medical Centre - Portland
North Carolina
- Wake Forest - Winston-Salem
Alberta
- University of Calgary - Calgary
Nova Scotia
- Maritime Heart Centre - Halifax
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 250 participants |
| Start Date | 2011-03 |
| Est. Completion | 2013-01 |
| Phase | NA |
What the finished NCT01071265 record still lists
NCT01071265 is an interventional study that assigns participants to a tested intervention. The registered 250 participants enrollment target is mid-sized for trials with a published cap, below the 732-participant average among 19 other Cardiac Surgery trials with a reported enrollment target (66% lower).
The record links to 1 condition, with Cardiac Surgery appearing as the primary indexed condition, and to 2 interventions - of which Sham is the first listed.
NCT01071265 lists 7 locations in 5 states (Ontario, Maine, North Carolina).
Frequently Asked Questions
What is clinical trial NCT01071265 about?
NCT01071265 is a clinical study titled "Remote Ischemic Preconditioning in Cardiac Surgery Trial". Main Research Questions: 1. Is a large trial of patients undergoing heart surgery comparing a simple procedure of temporarily stopping blood flow to the leg with a blood pressure cuff (called remote ischemic preconditioning) to a sham procedure possible? 2. Does the remote ischemic preconditioning ...
What is the current status of trial NCT01071265?
This trial is currently completed. It is a NA study. The enrollment target is 250 participants. The study started on 2011-03. Estimated completion is 2013-01.
What conditions does trial NCT01071265 study?
This clinical trial studies the following conditions: Cardiac Surgery.
What interventions are being tested in trial NCT01071265?
The interventions under investigation include: Sham (PROCEDURE), Remote Ischemic Preconditioning (PROCEDURE).
Who is sponsoring clinical trial NCT01071265?
This trial is sponsored by McMaster University, which has 31 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01071265 being conducted?
This trial has 7 study locations across Maine, North Carolina, Alberta, Nova Scotia, Ontario. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01071265's enrollment target sits among peer trials
250 6th of 19 higher than 14 of 19 other Cardiac Surgery trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cardiac Surgery trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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