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ClinicalTrials.gov 3 recruiting now early-phase tilt small index

Adrenocortical Carcinoma: early-phase trial registry

3 of 10 indexed Adrenocortical Carcinoma trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,724 of 28,707 conditions by registered trial count.

10 US clinical trials · 3 currently recruiting · #1,724 of 28,707 conditions by registered trial count

Adrenocortical Carcinoma: 10 US clinical trials tracked, 3 recruiting.

Adrenocortical Carcinoma is the subject of 10 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 2 of these trials.

Enrollment posture brief

Registry condition adrenocortical-carcinoma

OPEN 3 | RECR 30% | LATE 0 | EARLY 7 | RANK #1724 | SPON 2

Nearest open-share peer: Alcohol; Harmful Use (30% recruiting · 10 trials)

Acute Leukemia of Ambiguous 80%Achondroplasia40%Adrenocortical Carcinoma (th…30%Accelerated Phase Chronic My20%Accidental Fall20%
Open-enrollment share among volume-matched conditions near Adrenocortical Carcinoma

Adrenocortical Carcinoma lists 3 open slots (30% of 10 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Adrenocortical Carcinoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Adrenocortical Carcinoma is recruiting below its size-band peers.

    3 of 10 indexed trials (30%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Adrenocortical Carcinoma research.

    Memorial Sloan Kettering Cancer Center accounts for 2 of 10 trials (20%). 9 distinct sponsors appear on at least one study for this condition label.

  3. Most Adrenocortical Carcinoma trials plan to enrol fewer than 100 people.

    Median target enrolment is 68 among the 9 trials that report a genuine target (sentinel values excluded). 6 of those (66.7%) plan for fewer than 100 participants.

  4. Adrenocortical Carcinoma research is mostly interventional.

    7 interventional and 3 observational studies make up this index (70% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 13Phase 24

Open and recent trials

10 total, page 1 of 1

RECRUITING 1,500 participants

Familial Investigations of Childhood Cancer Predisposition

St. Jude Children's Research Hospital

NCT03050268

RECRUITING Phase 2 30 participants

Surgery and Heated Intraperitoneal Chemotherapy for Adrenocortical Carcinoma

Columbia University

NCT03127774

RECRUITING Phase 2 12 participants

Study of Radiotherapy and Pembrolizumab in People With Adrenocortical Carcinoma

Memorial Sloan Kettering Cancer Center

NCT06066333

ACTIVE NOT RECRUITING 1,000 participants

Optimal Methods of Disease Progression and Survival Analysis in Children and Adults Patients With Adrenocortical Cancer (ACC)

National Cancer Institute (NCI)

NCT04358107

ACTIVE NOT RECRUITING Phase 2 100 participants

Nivolumab Combined With Ipilimumab for Patients With Advanced Rare Genitourinary Tumors

Dana-Farber Cancer Institute

NCT03333616

ACTIVE NOT RECRUITING Phase 2 39 participants

Single Agent Pembrolizumab in Subjects With Advanced Adrenocortical Carcinoma

Memorial Sloan Kettering Cancer Center

NCT02673333

COMPLETED 97 participants

Natural History Study of Infants With Adrenal Masses Found on Prenatal and/or Neonatal Imaging

Children's Oncology Group

NCT00445718

COMPLETED Phase 1 68 participants

A Dose Finding Study of TKM-080301 Infusion in Neuroendocrine Tumors (NET) and Adrenocortical Carcinoma (ACC) Patients

Arbutus Biopharma Corporation

NCT01262235

COMPLETED Phase 1 63 participants

Phase 1 Study of ATR-101 in Subjects With Advanced Adrenocortical Carcinoma

Millendo Therapeutics

NCT01898715

COMPLETED Phase 1

Combination Chemotherapy With Suramin Plus Doxorubicin in Treating Patients With Advanced Solid Tumors

Mayo Clinic

NCT00003038

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 4

Named interventions

Most-linked intervention names on Adrenocortical Carcinoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Pembrolizumab Drug
2 trials
TKM-080301 Drug
1 trials
suramin Drug
1 trials
ATR-101 Drug
1 trials
Abdominal Sonogram Procedure
1 trials
3-Tesla magnetic resonance imaging Procedure
1 trials
doxorubicin hydrochloride Drug
1 trials
computed tomography Procedure
1 trials

US sites by state

Facility locations filed on Adrenocortical Carcinoma trials. A trial with sites in several states counts in each.

New York 4 trials
Texas 3 trials
Michigan 3 trials
Massachusetts 3 trials
Florida 3 trials
New Jersey 2 trials
Minnesota 2 trials
Maryland 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Adrenocortical Carcinoma page

10 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Adrenocortical Carcinoma condition card totals 10 registered trials; most-linked intervention Pembrolizumab; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.