Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 279 recruiting now early-phase tilt #6 of 28,963 conditions

Cancer: early-phase trial registry

279 of 621 indexed Cancer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #6 of 28,963 conditions by registered trial count.

621 US clinical trials · 279 currently recruiting · #6 of 28,963 conditions by registered trial count

Cancer: 621 US clinical trials tracked, 279 recruiting.

Cancer is the subject of 621 registered US clinical trials on ClinicalTrials.gov, 279 of them currently open to new participants. 31 are in Phase 3-4 (later-stage) and 164 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 31 of these trials.

Open enrollment, early-phase tilt

Cancer has 621 registered US clinical trials, 279 of them open to new participants right now, about 45% of the total.

279
recruiting participants now
45%
of trials open to enrollment
31
in Phase 3-4 (later-stage)
31
top sponsor: M.D. Anderson Cancer Center

Corpus placement: #6 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.

Key findings

What ClinicalTrials.gov does not surface for Cancer on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.

  1. Cancer is recruiting above its size-band peers.

    279 of 621 indexed trials (44.9%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Cancer trials is spread across many organizations.

    M.D. Anderson Cancer Center accounts for 31 of 621 trials (5%). 270 distinct sponsors appear on at least one study for this condition label.

  3. Typical Cancer enrolment sits around 108 participants.

    Median target enrolment is 108 among the 616 trials that report a genuine target (sentinel values excluded). 287 of those (46.6%) plan for fewer than 100 participants.

  4. Cancer research is mostly interventional.

    462 interventional and 159 observational studies make up this index (74.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 1116Phase 248Phase 327Phase 44

Open and recent trials

621 total, page 7 of 13

ACTIVE NOT RECRUITING Phase 2 350 participants

9-ING-41 in Patients with Advanced Cancers

Actuate Therapeutics

NCT03678883

ACTIVE NOT RECRUITING NA 344 participants

Nurse AMIE (Addressing Malignancies in Individuals Everyday)

University of Pittsburgh

NCT05221606

ACTIVE NOT RECRUITING NA 313 participants

Onco-primary Care Networking to Support TEAM-based Care

Duke University

NCT04258813

ACTIVE NOT RECRUITING NA 304 participants

Optimization of a mHealth Physical Activity Promotion Intervention With Mindful Awareness for AYAO (OPT2MOVE)

Northwestern University

NCT05375162

ACTIVE NOT RECRUITING NA 300 participants

Construal Level as a Novel Pathway for Affect Regulation and Cancer Control

University of Oregon

NCT04620915

ACTIVE NOT RECRUITING 300 participants

Adolescent and Young Adult Cancer Survivors: Identity Development

Memorial Sloan Kettering Cancer Center

NCT00832325

ACTIVE NOT RECRUITING Phase 1 276 participants

Phase 1 Trial of LVGN6051 as Single Agent and in Combination With Keytruda (Pembrolizumab) in Advanced or Metastatic Malignancy

Lyvgen Biopharma Holdings Limited

NCT04130542

ACTIVE NOT RECRUITING NA 256 participants

Decision Support Training for Advanced Cancer Family Caregivers: The CASCADE Factorial Trial

University of Alabama at Birmingham

NCT04803604

ACTIVE NOT RECRUITING NA 250 participants

Guaranteed Income and Financial Treatment

Meredith Doherty, PhD, LCSW

NCT06611982

ACTIVE NOT RECRUITING NA 236 participants

Surgery for Cancer With Option of Palliative Care Expert

Vanderbilt University Medical Center

NCT03436290

ACTIVE NOT RECRUITING NA 216 participants

Using Information Technology to Improve Outcomes for Children Living With Cancer

Northwestern University

NCT04789720

ACTIVE NOT RECRUITING NA 208 participants

Understanding Quality of Life Among Patients With Cancer Receiving Palliative Care

Abramson Cancer Center at Penn Medicine

NCT05331625

ACTIVE NOT RECRUITING NA 187 participants

SMLI With Hispanic Cancer Survivors and Caregivers

University of Arizona

NCT05364372

ACTIVE NOT RECRUITING NA 172 participants

EMPOWER 3: Improving Palliative Care Health Literacy and Utilization

Tulane University

NCT04733469

ACTIVE NOT RECRUITING NA 170 participants

Developing a Culturally Relevant Supportive Care Program for Black Patients Dealing With Advanced Cancer

M.D. Anderson Cancer Center

NCT05763797

ACTIVE NOT RECRUITING Phase 3 165 participants

An Extension Study of Venetoclax for Subjects Who Have Completed a Prior Venetoclax Clinical Trial

AbbVie

NCT03844048

ACTIVE NOT RECRUITING NA 162 participants

Increasing HPV Vaccination in Pediatric, Adolescent, and Young Adult (PAYA) Cancer Survivors

Masonic Cancer Center, University of Minnesota

NCT05665543

ACTIVE NOT RECRUITING 150 participants

Improving Outcomes for Older Adults Undergoing Radiation Therapy

Icahn School of Medicine at Mount Sinai

NCT05721053

ACTIVE NOT RECRUITING Phase 1 150 participants

A Study to Determine the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ABBV-927 With ABBV-368, Budigalimab (ABBV-181) and/or Chemotherapy in Participants With Locally Advanced or Metastatic Solid Tumors

AbbVie

NCT03893955

ACTIVE NOT RECRUITING Phase 1 137 participants

ENB003 Plus Pembrolizumab Phase 1b/2a in Solid Tumors

ENB Therapeutics

NCT04205227

ACTIVE NOT RECRUITING Phase 2 126 participants

Chemoradiation vs Immunotherapy and Radiation for Head and Neck Cancer

Loren Mell, MD

NCT03383094

ACTIVE NOT RECRUITING Phase 1 126 participants

Phase 1 Trial of LVGN7409 (CD40 Agonist Antibody) as Single Agent and Combination Therapies in Advanced or Metastatic Malignancy

Lyvgen Biopharma Holdings Limited

NCT04635995

ACTIVE NOT RECRUITING NA 124 participants

A Study of a Telemedicine Program for Older Adults With Cancer

Memorial Sloan Kettering Cancer Center

NCT04917848

ACTIVE NOT RECRUITING NA 120 participants

IGNITE Firefighters' Health

Stanford University

NCT06567561

ACTIVE NOT RECRUITING Phase 2 120 participants

Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes (PRECISION 1)

Aadi Bioscience

NCT05103358

ACTIVE NOT RECRUITING NA 115 participants

DASH INtervention to INvestigate the Gut

H. Lee Moffitt Cancer Center and Research Institute

NCT04538482

ACTIVE NOT RECRUITING 112 participants

Cancer Survivor Cardiomyopathy Detection

Mayo Clinic

NCT05201014

ACTIVE NOT RECRUITING NA 110 participants

Supportive Oncology Care at Home Post-Discharge

Massachusetts General Hospital

NCT04637035

ACTIVE NOT RECRUITING 100 participants

Technology to Assess Vulnerable Older Adults With Cancer and Their Caregivers

City of Hope Medical Center

NCT02041416

ACTIVE NOT RECRUITING NA 100 participants

Ovarian Tissue Cryopreservation in Children

Mayo Clinic

NCT02646384

ACTIVE NOT RECRUITING 100 participants

The Use of Cannabis (Marijuana) and Cannabidiol (CBD) Among Cancer Patients: A Pilot Study

M.D. Anderson Cancer Center

NCT05836857

ACTIVE NOT RECRUITING NA 91 participants

Addressing Financial and Social Needs Among Patients With Cancer

University of California, Irvine

NCT06430840

ACTIVE NOT RECRUITING 80 participants

Digitally-Captured Step Counts for Evaluating Performance Status in Advanced Cancer Patients

Cedars-Sinai Medical Center

NCT03757182

ACTIVE NOT RECRUITING Phase 1 80 participants

Decreasing Polypharmacy in Older Adults With Curable Cancers Trial

University of Rochester

NCT05046171

ACTIVE NOT RECRUITING NA 80 participants

Motivational Interviewing for Physical Activity

M.D. Anderson Cancer Center

NCT01008787

ACTIVE NOT RECRUITING NA 72 participants

A Stress Management and Resiliency Program for Adolescent and Young Adult Survivors

Massachusetts General Hospital

NCT03768336

ACTIVE NOT RECRUITING NA 70 participants

Electroacupuncture for the Management of Symptom Clusters in Cancer Patients and Survivors

University of California, Irvine

NCT05283577

ACTIVE NOT RECRUITING 69 participants

Biomarkers of Immune-Related Toxicity

University of Colorado, Denver

NCT03409016

ACTIVE NOT RECRUITING Phase 2 68 participants

Testing an Herbal Pain Relief Patch to Reduce Pain in Cancer Survivors

Memorial Sloan Kettering Cancer Center

NCT04916249

ACTIVE NOT RECRUITING Phase 1 65 participants

An Efficacy and Safety Study of Cofetuzumab Pelidotin in Participants With PTK7-Expressing, Recurrent Non-Small Cell Lung Cancer

AbbVie

NCT04189614

ACTIVE NOT RECRUITING NA 60 participants

Better Real-time Information on Documentation of Goals of Care for Engagement in Serious Illness Communication

Dana-Farber Cancer Institute

NCT07147023

ACTIVE NOT RECRUITING Phase 1 58 participants

AZD6244 (ARRY-142886) Solid Oral Dosage Formulation in Participants With Advanced Solid Malignancies

AstraZeneca

NCT00463814

ACTIVE NOT RECRUITING 55 participants

Assessing Reproductive Outcomes in Young Female Cancer Survivors Through a National Fertility Preservation Registry

University of California, San Diego

NCT01843140

ACTIVE NOT RECRUITING Phase 1 50 participants

A Study of TAVO412 in Patients with Cancer

Tavotek Biotherapeutics

NCT05548634

ACTIVE NOT RECRUITING 50 participants

Opiophobia in Adults With Advanced Cancer

M.D. Anderson Cancer Center

NCT07093567

ACTIVE NOT RECRUITING Phase 1 50 participants

A Pilot Trial of Atorvastatin in Tumor Protein 53 (p53) -Mutant and p53 Wild-Type Malignancies

Joaquina Baranda

NCT03560882

ACTIVE NOT RECRUITING Phase 1 48 participants

CAR-macrophages for the Treatment of HER2 Overexpressing Solid Tumors

Carisma Therapeutics

NCT04660929

ACTIVE NOT RECRUITING Phase 2 46 participants

Sirolimus in Combination With Metronomic Chemotherapy in Children With Recurrent and/or Refractory Solid and CNS Tumors

Emory University

NCT02574728

ACTIVE NOT RECRUITING Phase 1 44 participants

A Dose Escalation Study of HBI-2438 in Patients With Solid Tumors Harboring KRAS G12C Mutation

HUYABIO International

NCT05485974

ACTIVE NOT RECRUITING NA 44 participants

Use of Transcranial Photobiomodulation to Improve Cognition and Self-Reported Outcomes in Survivors of Childhood Cancer

St. Jude Children's Research Hospital

NCT05550948

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Phase Distribution

PhaseTrial count
Phase 1 116
Phase 2 48
Phase 3 27
Phase 4 4

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What is open for Cancer right now

279 recruiting of 621 indexed (45% open).

Phase mix: 31 late (III/IV) vs 164 early (I/II) (early-phase heavy).

Top sponsor: M.D. Anderson Cancer Center (31 trials), 9 others listed. 50 shown below, recruiting first. #6 of 28,963 conditions by registered trial count.

How open-enrollment share is computed

Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.

Frequently Asked Questions

How many clinical trials are there for Cancer?

PlainTrial tracks 621 US clinical trials for Cancer, of which 279 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.