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NCT00380029 · ClinicalTrials.gov registry record · Phase 2

Erlotinib Before and After Surgery in Treating Patients With Muscle-Invasive Bladder Cancer

A Phase 2 study of Bladder Cancer, sponsored by UNC Lineberger Comprehensive Cancer Center.

Completed
Registry status
Phase 2
Development phase
27
Enrollment target
1
Study location

NCT00380029 is a Phase 2 study of Bladder Cancer that has completed, run by UNC Lineberger Comprehensive Cancer Center. The registered enrollment target is 27 participants, below the 12,754-participant average among 175 other Bladder Cancer trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00380029, a Phase 2 study of Bladder Cancer, has completed, sponsored by UNC Lineberger Comprehensive Cancer Center.

COMPLETED
Registry status
Phase 2
Development phase
27 participants
Enrollment target
1
Study location

Study Summary

RATIONALE: Erlotinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving erlotinib before surgery may make the tumor smaller and reduce the amount of normal tissue that needs to be removed. Giving erlotinib after surgery may kill any tumor cells that remain after surgery. PURPOSE: This phase II trial is studying how well erlotinib works when given before and after surgery in treating patients with muscle-invasive bladder cancer.

Conditions Studied

Interventions

  • DRUG Erlotinib
  • PROCEDURE Radical Cystectomy

Study Locations (1)

North Carolina

  • Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill - Chapel Hill

Trial Details

FieldValue
Enrollment Target 27 participants
Start Date 2006-05
Est. Completion 2014-06
Phase Phase 2

What the Registry Record Tells You About NCT00380029

The ClinicalTrials.gov registry entry for NCT00380029 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 27 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 12,754-participant average among 175 other Bladder Cancer trials with a reported enrollment target (100% lower). The listed sponsor is UNC Lineberger Comprehensive Cancer Center, which has 366 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Bladder Cancer appearing as the primary indexed condition, and to 2 interventions - of which Erlotinib is the first listed.

NCT00380029 reports 1 study location spanning 1 distinct geographic area - top geographies include North Carolina.

Frequently Asked Questions

What is clinical trial NCT00380029 about?

NCT00380029 is a clinical study titled "Erlotinib Before and After Surgery in Treating Patients With Muscle-Invasive Bladder Cancer". RATIONALE: Erlotinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving erlotinib before surgery may make the tumor smaller and reduce the amount of normal tissue that needs to be removed. Giving erlotinib after surgery may kill any tumor cells that rem...

What is the current status of trial NCT00380029?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 27 participants. The study started on 2006-05. Estimated completion is 2014-06.

What conditions does trial NCT00380029 study?

This clinical trial studies the following conditions: Bladder Cancer.

What interventions are being tested in trial NCT00380029?

The interventions under investigation include: Erlotinib (DRUG), Radical Cystectomy (PROCEDURE).

Who is sponsoring clinical trial NCT00380029?

This trial is sponsored by UNC Lineberger Comprehensive Cancer Center, which has 366 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00380029 being conducted?

This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.