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NCT00001375 · ClinicalTrials.gov registry record
The Pathogenesis of Inflammatory Synovitis: A Study of Early Arthritis
A clinical trial of Arthritis and Arthritis, Rheumatoid, sponsored by National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS).
- Completed
- Registry status
- 500
- Enrollment target
- 1
- Study location
NCT00001375: Completed study of Arthritis and Arthritis, Rheumatoid, sponsored by National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS).
NCT00001375 is a study of Arthritis and Arthritis, Rheumatoid that has completed, run by National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). The registered enrollment target is 500 participants, below the 4,500-participant average among 48 other Arthritis trials with a reported enrollment target (89% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00001375, a study of Arthritis and Arthritis, Rheumatoid, has completed, sponsored by National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS).
- COMPLETED
- Registry status
- 500 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will evaluate patients with inflammatory forms of arthritis within the first year of onset. The study will attempt to clarify factors that may predict disease course such as evolution into rheumatoid arthritis (RA) or other chronic inflammatory arthropathies. Synovial biopsies and synovial fluid will be obtained to search for microbial agents and other initiating and modulating factors that may be most readily distinguished early in the disease and to determine the stage of disease at which certain immunologic and hormonal changes become evident. The study will also search for genetic and other features that may be associated with specific forms of inflammatory arthropathies that might predict the subsequent clinical disease course or response to different agents used in treatment of RA, Reiter's syndrome and other types of chronic inflammatory arthropathies.
Conditions Studied
Study Locations (1)
Maryland
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 500 participants |
| Start Date | 1994-08 |
| Est. Completion | 2000-06 |
Sponsor
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)93 total trials
What the finished NCT00001375 record still lists
NCT00001375 is an observational study that tracks outcomes without assigning an intervention. The registered 500 participants enrollment target is mid-sized for trials with a published cap, below the 4,500-participant average among 48 other Arthritis trials with a reported enrollment target (89% lower).
The record links to 5 conditions, with Arthritis appearing as the primary indexed condition, and to 0 interventions.
NCT00001375 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT00001375 about?
NCT00001375 is a clinical study titled "The Pathogenesis of Inflammatory Synovitis: A Study of Early Arthritis". This study will evaluate patients with inflammatory forms of arthritis within the first year of onset. The study will attempt to clarify factors that may predict disease course such as evolution into rheumatoid arthritis (RA) or other chronic inflammatory arthropathies. Synovial biopsies and synovia...
What is the current status of trial NCT00001375?
This trial is currently completed. The enrollment target is 500 participants. The study started on 1994-08. Estimated completion is 2000-06.
What conditions does trial NCT00001375 study?
This clinical trial studies the following conditions: Arthritis, Arthritis, Rheumatoid, Synovitis, Arthritis, Reactive, Reiter's Disease.
Who is sponsoring clinical trial NCT00001375?
This trial is sponsored by National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), which has 93 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00001375 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT00001375's enrollment target sits among peer trials
500 8th of 48 higher than 41 of 48 other Arthritis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Arthritis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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