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NCT00001375 · ClinicalTrials.gov registry record

The Pathogenesis of Inflammatory Synovitis: A Study of Early Arthritis

A clinical trial of Arthritis and Arthritis, Rheumatoid, sponsored by National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS).

Completed
Registry status
500
Enrollment target
1
Study location

NCT00001375 is a study of Arthritis and Arthritis, Rheumatoid that has completed, run by National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). The registered enrollment target is 500 participants, below the 4,500-participant average among 48 other Arthritis trials with a reported enrollment target (89% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00001375, a study of Arthritis and Arthritis, Rheumatoid, has completed, sponsored by National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS).

COMPLETED
Registry status
500 participants
Enrollment target
1
Study location

Study Summary

This study will evaluate patients with inflammatory forms of arthritis within the first year of onset. The study will attempt to clarify factors that may predict disease course such as evolution into rheumatoid arthritis (RA) or other chronic inflammatory arthropathies. Synovial biopsies and synovial fluid will be obtained to search for microbial agents and other initiating and modulating factors that may be most readily distinguished early in the disease and to determine the stage of disease at which certain immunologic and hormonal changes become evident. The study will also search for genetic and other features that may be associated with specific forms of inflammatory arthropathies that might predict the subsequent clinical disease course or response to different agents used in treatment of RA, Reiter's syndrome and other types of chronic inflammatory arthropathies.

Study Locations (1)

Maryland

  • National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) - Bethesda

Trial Details

FieldValue
Enrollment Target 500 participants
Start Date 1994-08
Est. Completion 2000-06

What the Registry Record Tells You About NCT00001375

The ClinicalTrials.gov registry entry for NCT00001375 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 500 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 4,500-participant average among 48 other Arthritis trials with a reported enrollment target (89% lower). The listed sponsor is National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), which has 93 total studies on file at ClinicalTrials.gov.

The record links to 5 conditions, with Arthritis appearing as the primary indexed condition, and to 0 interventions.

NCT00001375 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.

Frequently Asked Questions

What is clinical trial NCT00001375 about?

NCT00001375 is a clinical study titled "The Pathogenesis of Inflammatory Synovitis: A Study of Early Arthritis". This study will evaluate patients with inflammatory forms of arthritis within the first year of onset. The study will attempt to clarify factors that may predict disease course such as evolution into rheumatoid arthritis (RA) or other chronic inflammatory arthropathies. Synovial biopsies and synovia...

What is the current status of trial NCT00001375?

This trial is currently completed. The enrollment target is 500 participants. The study started on 1994-08. Estimated completion is 2000-06.

What conditions does trial NCT00001375 study?

This clinical trial studies the following conditions: Arthritis, Arthritis, Rheumatoid, Synovitis, Arthritis, Reactive, Reiter's Disease.

Who is sponsoring clinical trial NCT00001375?

This trial is sponsored by National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), which has 93 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00001375 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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