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NCT00646906 · ClinicalTrials.gov registry record · NA
Mechanisms of Action of Acetaminophen
A NA study of Myocardial Infarction and Arthritis, sponsored by University of Pennsylvania.
- Completed
- Registry status
- NA
- Development phase
- 55
- Enrollment target
- 1
- Study location
NCT00646906 is a NA study of Myocardial Infarction and Arthritis that has completed, run by University of Pennsylvania. The registered enrollment target is 55 participants, below the 4,681-participant average among 64 other Myocardial Infarction trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.
The verdict
NCT00646906, a NA study of Myocardial Infarction and Arthritis, has completed, sponsored by University of Pennsylvania.
- COMPLETED
- Registry status
- NA
- Development phase
- 55 participants
- Enrollment target
- 1
- Study location
Study Summary
This research study investigates whether the ability of aspirin to reduce the risk of heart attacks may be diminished by the administration of acetaminophen. Patients who have heart disease are often prescribed aspirin because of its unique ability to permanently prevent platelets from aggregating and forming a blood clot. Such blood clots cause heart attacks when they form in a blood vessel that supplies the heart with oxygen rich blood. Some of these same patients also take acetaminophen everyday for relief from arthritis pain. Higher doses of acetaminophen may also have the ability to prevent the platelets from clotting, however only temporarily. Therefore, this study evaluates whether the timing of the administration of acetaminophen (before or after aspirin) interferes with the permanent blood clotting effects of aspirin. The primary hypothesis is that acetaminophen given two hours before aspirin will antagonize the effects of aspirin, while reversing the order of administration will not.
Conditions Studied
Interventions
- DRUG Aspirin First
- DRUG Aspirin Last
- DRUG Acetaminophen 1000 mg/d
- DRUG Acetaminophen 4000 mg/d
- DRUG Ibuprofen 800 mg/d
Study Locations (1)
Pennsylvania
- Hospital of The University of Pennsylvania - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 55 participants |
| Start Date | 2004-06-02 |
| Est. Completion | 2012-01-24 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00646906
The ClinicalTrials.gov registry entry for NCT00646906 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 55 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 4,681-participant average among 64 other Myocardial Infarction trials with a reported enrollment target (99% lower). The listed sponsor is University of Pennsylvania, which has 1,423 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Myocardial Infarction appearing as the primary indexed condition, and to 5 interventions - of which Aspirin First is the first listed.
NCT00646906 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT00646906 about?
NCT00646906 is a clinical study titled "Mechanisms of Action of Acetaminophen". This research study investigates whether the ability of aspirin to reduce the risk of heart attacks may be diminished by the administration of acetaminophen. Patients who have heart disease are often prescribed aspirin because of its unique ability to permanently prevent platelets from aggregating a...
What is the current status of trial NCT00646906?
This trial is currently completed. It is a NA study. The enrollment target is 55 participants. The study started on 2004-06-02. Estimated completion is 2012-01-24.
What conditions does trial NCT00646906 study?
This clinical trial studies the following conditions: Myocardial Infarction, Arthritis.
What interventions are being tested in trial NCT00646906?
The interventions under investigation include: Aspirin First (DRUG), Aspirin Last (DRUG), Acetaminophen 1000 mg/d (DRUG), Acetaminophen 4000 mg/d (DRUG), Ibuprofen 800 mg/d (DRUG).
Who is sponsoring clinical trial NCT00646906?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00646906 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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