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NCT04456569 · ClinicalTrials.gov registry record · NA
Geniculate Artery Embolization for Osteoarthritis
A NA study of Osteoarthritis and Osteoarthritis, Knee, sponsored by University of Minnesota.
- Recruiting
- Registry status
- NA
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT04456569: Recruiting NA study of Osteoarthritis and Osteoarthritis, Knee, sponsored by University of Minnesota.
NCT04456569 is a NA study of Osteoarthritis and Osteoarthritis, Knee that is actively recruiting participants, run by University of Minnesota. The registered enrollment target is 20 participants, below the 818-participant average among 135 other Osteoarthritis trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04456569, a NA study of Osteoarthritis and Osteoarthritis, Knee, is actively recruiting participants, sponsored by University of Minnesota.
- RECRUITING
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
The need for exploration of more definitive and cost effective non-arthroplasty treatments of osteoarthritis (OA) has been demonstrated by the orthopedic and health economic research. Embolotherapy of neovessels associated with OA joints has been shown to be promising in patients with knee OA. There is a need for level one evidence drawn from randomized clinical trials to prove the safety, feasibility and efficacy of knee embolotherapy compared to standard of care. This randomized pilot study will assign 10 patients with mild-moderate OA to undergo geniculate artery embolization plus standard of care (defined in this study as: physical therapy and oral anti-inflammatory medications, with a maximum of 1 joint injection at the time of enrollment) and 10 patients to receive only medical standard of care (also having had a maximum of 1 joint injection prior to enrollment). The goal of this pilot study is to obtain preliminary estimates of safety and efficacy of embolotherapy to provide sustained symptom control and modify disease progression in patients with mild to moderate knee OA.
Primary Outcome
Safety will be reported using the combined number of grade 3 and 4 adverse events that occur in each arm.
Conditions Studied
Interventions
- DEVICE Geniculate Artery Embolization
Study Locations (1)
Minnesota
- University of Minnesota - Minneapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2022-02-01 |
| Est. Completion | 2027-03-01 |
| Phase | NA |
What NCT04456569 shows while recruiting
NCT04456569 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 818-participant average among 135 other Osteoarthritis trials with a reported enrollment target (98% lower).
The record links to 3 conditions, with Osteoarthritis appearing as the primary indexed condition, and to 1 intervention - of which Geniculate Artery Embolization is the first listed.
NCT04456569 reports a single indexed study location in Minnesota.
Frequently Asked Questions
What is clinical trial NCT04456569 about?
NCT04456569 is a clinical study titled "Geniculate Artery Embolization for Osteoarthritis". The need for exploration of more definitive and cost effective non-arthroplasty treatments of osteoarthritis (OA) has been demonstrated by the orthopedic and health economic research. Embolotherapy of neovessels associated with OA joints has been shown to be promising in patients with knee OA. Ther...
What is the current status of trial NCT04456569?
This trial is currently recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2022-02-01. Estimated completion is 2027-03-01.
What conditions does trial NCT04456569 study?
This clinical trial studies the following conditions: Osteoarthritis, Osteoarthritis, Knee, Arthritis.
What interventions are being tested in trial NCT04456569?
The interventions under investigation include: Geniculate Artery Embolization (DEVICE).
Who is sponsoring clinical trial NCT04456569?
This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04456569 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Osteoarthritis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04456569's enrollment target sits among peer trials
20 133rd of 135 higher than 2 of 135 other Osteoarthritis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Osteoarthritis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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