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NCT05844124 · ClinicalTrials.gov registry record · NA
Impact of Different Exercise Programs on Knee OA
A NA study of Osteoarthritis and Knee Osteoarthritis, sponsored by Shirley Ryan AbilityLab.
- Active
- Registry status
- NA
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT05844124 is a NA study of Osteoarthritis and Knee Osteoarthritis that is active but no longer recruiting, run by Shirley Ryan AbilityLab. The registered enrollment target is 60 participants, below the 817-participant average among 135 other Osteoarthritis trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05844124, a NA study of Osteoarthritis and Knee Osteoarthritis, is active but no longer recruiting, sponsored by Shirley Ryan AbilityLab.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will examine and compare the changes in serum biomarkers, joint kinematics, and thigh muscle strength based on three different 8-week exercise protocols in individuals with knee pathology: Lower-body positive-pressure (LBPP) supported low-load treadmill walking and Aquatic exercise program and standard of care treadmill or community walking. Investigators hypothesize that both the 8-week exercise programs which aim to partially off-load the knee joint will be associated with a significant reduction in serum biological markers of joint disease (tissue turnover, cartilage degradation and inflammation) in response to the exercise. The serum biological markers will be directly correlated to participant reported knee pain. Both the LBPP-supported low-load and the aquatic exercise regimens will result in significant increases in thigh muscle strength about the degenerative knee which in-turn will result in diminished knee pain and enhanced joint function. Investigators aim to compare these two exercise programs to understand if benefits of one far exceeds the other as compared to standard of care treadmill or community walking.
Conditions Studied
Interventions
- OTHER Exercise for Knee Osteoarthritis Recommendations (Control group)
- OTHER Exercise for Knee Osteoarthritis -(LBPP supported low-load treadmill Walking)
- OTHER Exercise for Knee Osteoarthritis - (Aquatic Walking)
Study Locations (1)
Illinois
- Shirley Ryan AbilityLab - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2023-04-01 |
| Est. Completion | 2025-07-31 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05844124
The ClinicalTrials.gov registry entry for NCT05844124 describes a study currently listed as active not recruiting, categorized as NA. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 817-participant average among 135 other Osteoarthritis trials with a reported enrollment target (93% lower). The listed sponsor is Shirley Ryan AbilityLab, which has 138 total studies on file at ClinicalTrials.gov.
The record links to 6 conditions, with Osteoarthritis appearing as the primary indexed condition, and to 3 interventions - of which Exercise for Knee Osteoarthritis Recommendations (Control group) is the first listed.
NCT05844124 reports 1 study location spanning 1 distinct geographic area - top geographies include Illinois.
Frequently Asked Questions
What is clinical trial NCT05844124 about?
NCT05844124 is a clinical study titled "Impact of Different Exercise Programs on Knee OA". This study will examine and compare the changes in serum biomarkers, joint kinematics, and thigh muscle strength based on three different 8-week exercise protocols in individuals with knee pathology: Lower-body positive-pressure (LBPP) supported low-load treadmill walking and Aquatic exercise progra...
What is the current status of trial NCT05844124?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2023-04-01. Estimated completion is 2025-07-31.
What conditions does trial NCT05844124 study?
This clinical trial studies the following conditions: Osteoarthritis, Knee Osteoarthritis, Arthritis, Musculoskeletal Diseases, Rheumatic Diseases.
What interventions are being tested in trial NCT05844124?
The interventions under investigation include: Exercise for Knee Osteoarthritis Recommendations (Control group) (OTHER), Exercise for Knee Osteoarthritis -(LBPP supported low-load treadmill Walking) (OTHER), Exercise for Knee Osteoarthritis - (Aquatic Walking) (OTHER).
Who is sponsoring clinical trial NCT05844124?
This trial is sponsored by Shirley Ryan AbilityLab, which has 138 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05844124 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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