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ClinicalTrials.gov 42 recruiting now full pipeline

Anxiety Disorders: full-pipeline trial registry

42 of 85 indexed Anxiety Disorders trials are currently recruiting.

Corpus placement: #165 of 28,707 conditions by registered trial count.

85 US clinical trials · 42 currently recruiting · #165 of 28,707 conditions by registered trial count

Anxiety Disorders: 85 US clinical trials tracked, 42 recruiting.

Anxiety Disorders is the subject of 85 registered US clinical trials on ClinicalTrials.gov, 42 of them currently open to new participants. 10 are in Phase 3-4 (later-stage) and 11 in Phase 1-2 (earlier-stage). The most active sponsor is Massachusetts General Hospital, running 5 of these trials.

Enrollment posture brief

Registry condition anxiety-disorders

OPEN 42 | RECR 49% | LATE 10 | EARLY 11 | RANK #165 | SPON 5

Nearest open-share peer: Metastatic Malignant Solid Neoplasm (49% recruiting · 93 trials)

Pancreatic Ductal Adenocarci65.9%Suicidal Ideation61.2%Anatomic Stage III Breast Ca56.5%Anxiety Disorders (this)49%Cataract23.5%
Open-enrollment share among volume-matched conditions near Anxiety Disorders

Anxiety Disorders lists 42 open slots (49% of 85 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Anxiety Disorders on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Anxiety Disorders is recruiting above its size-band peers.

    42 of 85 indexed trials (49.4%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Anxiety Disorders trials is spread across many organizations.

    Massachusetts General Hospital accounts for 5 of 85 trials (5.9%). 57 distinct sponsors appear on at least one study for this condition label.

  3. Typical Anxiety Disorders enrolment sits around 109 participants.

    Median target enrolment is 109 among the 85 trials that report a genuine target (sentinel values excluded). 39 of those (45.9%) plan for fewer than 100 participants.

  4. Anxiety Disorders research is mostly interventional.

    75 interventional and 10 observational studies make up this index (88.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 15Phase 26Phase 38Phase 42

Open and recent trials

85 total, page 1 of 2

RECRUITING 50,000 participants

RIVER At Home Ketamine Protocols

RIVER Foundation

NCT06070766

RECRUITING 16,000 participants

Evaluation of Patients With Mood and Anxiety Disorders and Healthy Volunteers

National Institute of Mental Health (NIMH)

NCT00024635

RECRUITING Phase 2 2,530 participants

Study of Neuro-Cognitive Correlates of Pediatric Anxiety Disorders

National Institute of Mental Health (NIMH)

NCT00018057

RECRUITING NA 2,500 participants

Clinical Study Evaluating Pharmacogenomics-informed Pharmacotherapy Versus Dosing as Usual in Psychiatric Disorders

Maastricht University Medical Center

NCT05656469

RECRUITING NA 2,448 participants

Enhancing Engagement by Integrating Goals and Concerns That Matter to Patients

Dartmouth-Hitchcock Medical Center

NCT06898593

RECRUITING NA 2,000 participants

Cultural Adaptation of a SSI for Youth Anxiety

University of Miami

NCT04729504

RECRUITING 1,500 participants

Resilience in Adolescent Development

University of Texas Southwestern Medical Center

NCT03458936

RECRUITING 1,000 participants

Technology Exposure and Child Health: Wellness Impact and Social Effects: an Observational Product Registry Study

Aura

NCT06664944

RECRUITING NA 600 participants

CRISOL Mente: A Multilevel Community Intervention to Reduce Mental Health Disparities Among Latinos

Drexel University

NCT06139159

RECRUITING 500 participants

Ketamine Treatment Plans for Chronic Conditions

RIVER Foundation

NCT06038409

RECRUITING 390 participants

Development of Magnetic Resonance Imaging Techniques for Studying Mood and Anxiety Disorders

National Institute of Mental Health (NIMH)

NCT00397111

RECRUITING NA 306 participants

Enhancing Psychotherapy for Veterans and Service Members With PTSD and Anxiety

Baylor College of Medicine

NCT05843695

RECRUITING NA 240 participants

Neurostimulation Versus Therapy for Problems With Emotions

Duke University

NCT05712057

RECRUITING NA 238 participants

Whole Health in VA Mental Health: Omnis Salutis

VA Office of Research and Development

NCT05400252

RECRUITING 200 participants

An Exploratory Study Examining Biopsychosocial Markers of Anxiety and Depression

Singula Institute

NCT05466851

RECRUITING NA 200 participants

A Comparison of Two School Based Interventions to Manage Anxiety in Autistic Students

University of Colorado, Denver

NCT05863520

RECRUITING NA 192 participants

A Preventive Behavioral Intervention for Young Adults With Psychotic Experiences

Massachusetts General Hospital

NCT06929442

RECRUITING NA 180 participants

Respiratory Training in the Treatment of Transdiagnostic Pathological Anxiety

University of Texas at Austin

NCT05427708

RECRUITING Phase 4 165 participants

Processes and Circuitry Underlying Threat Sensitivity as a Treatment Target for Co-morbid Anxiety and Depression

Laureate Institute for Brain Research

NCT06004115

RECRUITING Phase 4 150 participants

Trial With the Treatment of Sertraline in Youth With Generalized, Separation and/or Social Anxiety Disorders.

University of Cincinnati

NCT04221997

RECRUITING Phase 2 150 participants

Gaze-Contingent Music Therapy Augmentation of CBT for Pediatric Anxiety

National Institute of Mental Health (NIMH)

NCT06595953

RECRUITING NA 150 participants

RXWell to Decrease Post-Operative Opioid Use in Total Knee or Hip Arthroplasty

University of Pittsburgh

NCT05658796

RECRUITING NA 139 participants

Internet-delivered Cognitive-Behavioral Therapy for Adolescents With Autism and Anxiety

Baylor College of Medicine

NCT06537128

RECRUITING Phase 2 128 participants

Enhancing Transdiagnostic Mechanisms of Cognitive Dyscontrol (R33)

University of California, San Diego

NCT06273527

RECRUITING NA 120 participants

Expansion and Evaluation of AI-generated Clinical Assessment (AI-COA®) of Depression and Anxiety Severity

Deliberate Solutions

NCT06923995

RECRUITING Phase 2 108 participants

Pramipexole to Enhance Social Connections

University of California, San Diego

NCT06269146

RECRUITING NA 100 participants

Reducing Mental Health Disparities Among Latinxs With a Telenovela Intervention

University of Nevada, Reno

NCT06163599

RECRUITING NA 96 participants

Pilot Effectiveness Trial of an ACT Self-help Workbook Tailored Specifically for Prisons

University of Wisconsin, Madison

NCT06162624

RECRUITING NA 95 participants

Initial Assessment of the Feasibility and Efficacy of a Scalable Digital CBT for Generalized Anxiety and Associated Health Behaviors in a Cardiovascular Disease Population

Boston University Charles River Campus

NCT04895995

RECRUITING NA 90 participants

Measurement-Based Care (MBC) Implementation, Effectiveness, and Mechanisms of Change

Carilion Clinic

NCT06671158

RECRUITING NA 90 participants

Online Parent Education for Child Anxiety

Massachusetts General Hospital

NCT07153250

RECRUITING Phase 3 90 participants

Cannabidiol-Assisted Learning for Managing Generalized Anxiety Disorder

Wayne State University

NCT07123467

RECRUITING NA 80 participants

Mindful Self-compassion for Anxiety and Depression: Impact of Delivery Method

Georgetown University

NCT07028216

RECRUITING NA 80 participants

Modulating Anxious Coping

Medical University of South Carolina

NCT04824105

RECRUITING NA 76 participants

Toward Understanding Drivers of Patient Engagement With Digital Mental Health Interventions - Part II

Brigham and Women's Hospital

NCT05555875

RECRUITING NA 70 participants

DINO RCT - Treating Anxiety in Children With Autism

Hugo W. Moser Research Institute at Kennedy Krieger

NCT06066983

RECRUITING NA 70 participants

Development of a Transdiagnostic Intervention for Adolescents at Risk for Serious Mental Illness

Massachusetts General Hospital

NCT05962879

RECRUITING NA 60 participants

Managing Anxiety in Pediatric Primary Care (MAPP)

UConn Health

NCT06104904

RECRUITING NA 54 participants

A Single Session Parenting Intervention for Children on a Outpatient Therapy Waitlist

Massachusetts General Hospital

NCT06043271

RECRUITING NA 40 participants

Mindful Self-Compassion for Anxiety Disorders and Depression

Georgetown University

NCT05671419

RECRUITING NA 40 participants

Modulating Escape Using Focused Ultrasound

Medical University of South Carolina

NCT06273904

RECRUITING NA 12 participants

Effectiveness of the SoundHeal Multi-Sensory Integrative Therapy Among Justice-Involved Youth

SoundHeal

NCT07364799

ACTIVE NOT RECRUITING Phase 3 316 participants

Fluoxetine vs CBT in Childhood Anxiety Disorders

Children's Hospital Los Angeles

NCT04760275

ACTIVE NOT RECRUITING NA 174 participants

Reconnecting to Ourselves and Others in Virtual Meetings (ROOM)

Massachusetts General Hospital

NCT06360562

ACTIVE NOT RECRUITING 60 participants

SKY Breath Intervention

University of California, San Francisco

NCT05388110

ACTIVE NOT RECRUITING NA 50 participants

TCI-Massage Clinical Trial

The Center for Victims of Torture, United States

NCT07482358

ACTIVE NOT RECRUITING NA 32 participants

Transitioning Emotionally and Academically to Middle School Successfully (TEAMSS)

UConn Health

NCT05145387

ACTIVE NOT RECRUITING NA 30 participants

Pre-Post Intervention Study to Investigate the Safety, Feasibility, & Efficacy of the NeurGear ZenBud System for the Treatment of Anxiety & Anxiety-Related Symptoms

NeurGear

NCT06574971

ACTIVE NOT RECRUITING NA 20 participants

Focused Ultrasound Amygdala Neuromodulation

University of Texas at Austin

NCT05228964

ACTIVE NOT RECRUITING NA 15 participants

PRISM for Depression and Anxiety in Young Adults With Cancer

Dana-Farber Cancer Institute

NCT06502483

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Phase Distribution

PhaseTrial count
Phase 1 5
Phase 2 6
Phase 3 8
Phase 4 2

Named interventions

Most-linked intervention names on Anxiety Disorders records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Mindful Self-Compassion Behavioral
2 trials
Fluoxetine Drug
2 trials
Diaphragmatic Breathing Behavioral
2 trials
CBT Behavioral
2 trials
Progressive Muscle Relaxation Behavioral
2 trials
Cognitive Behavioral Therapy (CBT) Behavioral
2 trials
Repetitive Transcranial Magnetic Stimulation (rTMS) Device
2 trials
Ketamine Drug
2 trials

US sites by state

Facility locations filed on Anxiety Disorders trials. A trial with sites in several states counts in each.

Massachusetts 15 trials
California 15 trials
Texas 8 trials
Maryland 8 trials
Florida 6 trials
Pennsylvania 5 trials
New York 5 trials
Connecticut 5 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Anxiety Disorders page

85 registered trials, 42 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Anxiety Disorders condition card totals 85 registered trials; most-linked intervention Mindful Self-Compassion; top US site state Massachusetts. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.