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NCT06273904 · ClinicalTrials.gov registry record · NA
Modulating Escape Using Focused Ultrasound
A NA study of Anxiety Disorders, sponsored by Medical University of South Carolina.
- Recruiting
- Registry status
- NA
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT06273904: Recruiting NA study of Anxiety Disorders, sponsored by Medical University of South Carolina.
NCT06273904 is a NA study of Anxiety Disorders that is actively recruiting participants, run by Medical University of South Carolina. The registered enrollment target is 40 participants, below the 1,139-participant average among 84 other Anxiety Disorders trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06273904, a NA study of Anxiety Disorders, is actively recruiting participants, sponsored by Medical University of South Carolina.
- RECRUITING
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a study to find out if a cutting-edge technology called transcranial focused ultrasound (tFUS) can be used to treat how people with anxiety or related concerns cope with emotional situations. tFUS is a brain stimulation technology that causes temporary changes in the activity of deep brain areas without a need for any surgery or other permanent or invasive procedures. This study is recruiting participants who recently started treatment for anxiety or a related concern to come in for 3 visits at the Medical University of South Carolina. At the first visit, participants will do interviews and surveys asking about anxiety and related concerns, and they do tasks where they respond to emotional pictures while brain activity is measured using magnetic resonance imaging (MRI). At the next two visits, participants again do a task where they see and react to emotional images, and this time the task is done once before and again once after receiving tFUS that either actively causes temporary changes (lasting for about an hour) in a targeted brain area or is not active (no changes elicited). At each tFUS visit, responses are measured with sensors worn on the hand, arms, face, and head (these visits do not involve MRI). Each visit in this study is expected to last between 2 - 3 hours. This study is not a treatment study, but it could help improve treatment in the future. Participants in this study are paid for their time.
Primary Outcome
Fear-potentiated startle is measured during an experimental task in which participants prepare to avoid, escape, or simply be exposed to aversive pictures. Fear-potentiated startle measures motivational activation during the preparation period.
Conditions Studied
Interventions
- DEVICE Active transcranial focused ultrasound (tFUS)
- DEVICE Sham transcranial focused ultrasound (tFUS)
Study Locations (1)
South Carolina
- Medical University of South Carolina - Charleston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2024-05-20 |
| Est. Completion | 2027-01 |
| Phase | NA |
What NCT06273904 shows while recruiting
NCT06273904 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 1,139-participant average among 84 other Anxiety Disorders trials with a reported enrollment target (96% lower).
The record links to 1 condition, with Anxiety Disorders appearing as the primary indexed condition, and to 2 interventions - of which Active transcranial focused ultrasound (tFUS) is the first listed.
NCT06273904 reports a single indexed study location in South Carolina.
Frequently Asked Questions
What is clinical trial NCT06273904 about?
NCT06273904 is a clinical study titled "Modulating Escape Using Focused Ultrasound". This is a study to find out if a cutting-edge technology called transcranial focused ultrasound (tFUS) can be used to treat how people with anxiety or related concerns cope with emotional situations. tFUS is a brain stimulation technology that causes temporary changes in the activity of deep brain a...
What is the current status of trial NCT06273904?
This trial is currently recruiting. It is a NA study. The enrollment target is 40 participants. The study started on 2024-05-20. Estimated completion is 2027-01.
What conditions does trial NCT06273904 study?
This clinical trial studies the following conditions: Anxiety Disorders.
What interventions are being tested in trial NCT06273904?
The interventions under investigation include: Active transcranial focused ultrasound (tFUS) (DEVICE), Sham transcranial focused ultrasound (tFUS) (DEVICE).
Who is sponsoring clinical trial NCT06273904?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06273904 being conducted?
This trial has 1 study location across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Anxiety Disorders
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06273904's enrollment target sits among peer trials
40 72nd of 84 higher than 10 of 84 other Anxiety Disorders trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Anxiety Disorders trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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