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NCT05427708 · ClinicalTrials.gov registry record · NA

Respiratory Training in the Treatment of Transdiagnostic Pathological Anxiety

A NA study of Post Traumatic Stress Disorder and Anxiety Disorders, sponsored by University of Texas at Austin.

Recruiting
Registry status
NA
Development phase
180
Enrollment target
1
Study location

NCT05427708: Recruiting NA study of Post Traumatic Stress Disorder and Anxiety Disorders, sponsored by University of Texas at Austin.

NCT05427708 is a NA study of Post Traumatic Stress Disorder and Anxiety Disorders that is actively recruiting participants, run by University of Texas at Austin. The registered enrollment target is 180 participants, below the 663-participant average among 262 other Post Traumatic Stress Disorder trials with a reported enrollment target (73% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05427708, a NA study of Post Traumatic Stress Disorder and Anxiety Disorders, is actively recruiting participants, sponsored by University of Texas at Austin.

RECRUITING
Registry status
NA
Development phase
180 participants
Enrollment target
1
Study location

Study Summary

Purpose of the Research: The primary aim of the proposed study is to conduct a randomized parallel-group 2-arm clinical trial investigating capnometry-guided respiratory intervention (CGRI) for pathological anxiety. CGRI aims to raise end-tidal CO2 levels thereby lowering hyperventilation-induced respiratory alkalosis and its associated fear-eliciting somatic reactions. Psycho-education about anxiety and its effects (PsyEd) will serve as a credible control comparator.

Primary Outcome

Change from baseline in self-reported transdiagnostic anxiety symptoms (range = 0 - 20, with higher scores indexing more symptoms).

Interventions

  • DEVICE Capnometry-Guided Respiratory Intervention
  • BEHAVIORAL Psycho-Education

Study Locations (1)

Texas

  • University of Texas at Austin - Austin

Trial Details

FieldValue
Enrollment Target 180 participants
Start Date 2022-08-22
Est. Completion 2027-05
Phase NA
University of Texas at Austin

257 total trials

What NCT05427708 shows while recruiting

NCT05427708 is an interventional study that assigns participants to a tested intervention. The registered 180 participants enrollment target is mid-sized for trials with a published cap, below the 663-participant average among 262 other Post Traumatic Stress Disorder trials with a reported enrollment target (73% lower).

The record links to 10 conditions, with Post Traumatic Stress Disorder appearing as the primary indexed condition, and to 2 interventions - of which Capnometry-Guided Respiratory Intervention is the first listed.

NCT05427708 reports a single indexed study location in Texas.

Frequently Asked Questions

What is clinical trial NCT05427708 about?

NCT05427708 is a clinical study titled "Respiratory Training in the Treatment of Transdiagnostic Pathological Anxiety". Purpose of the Research: The primary aim of the proposed study is to conduct a randomized parallel-group 2-arm clinical trial investigating capnometry-guided respiratory intervention (CGRI) for pathological anxiety. CGRI aims to raise end-tidal CO2 levels thereby lowering hyperventilation-induced re...

What is the current status of trial NCT05427708?

This trial is currently recruiting. It is a NA study. The enrollment target is 180 participants. The study started on 2022-08-22. Estimated completion is 2027-05.

What conditions does trial NCT05427708 study?

This clinical trial studies the following conditions: Post Traumatic Stress Disorder, Anxiety Disorders, Trauma, Generalized Anxiety Disorder, Social Anxiety Disorder.

What interventions are being tested in trial NCT05427708?

The interventions under investigation include: Capnometry-Guided Respiratory Intervention (DEVICE), Psycho-Education (BEHAVIORAL).

Who is sponsoring clinical trial NCT05427708?

This trial is sponsored by University of Texas at Austin, which has 257 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05427708 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Post Traumatic Stress Disorder

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05427708's enrollment target sits among peer trials

180 63rd of 262 higher than 198 of 262 other Post Traumatic Stress Disorder trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Post Traumatic Stress Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05427708, the US trial registry maintained by the National Library of Medicine. NCT05427708 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.