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NCT04824105 · ClinicalTrials.gov registry record · NA

Modulating Anxious Coping

A NA study of Anxiety Disorders, sponsored by Medical University of South Carolina.

Recruiting
Registry status
NA
Development phase
80
Enrollment target
1
Study location

NCT04824105: Recruiting NA study of Anxiety Disorders, sponsored by Medical University of South Carolina.

NCT04824105 is a NA study of Anxiety Disorders that is actively recruiting participants, run by Medical University of South Carolina. The registered enrollment target is 80 participants, below the 1,139-participant average among 84 other Anxiety Disorders trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04824105, a NA study of Anxiety Disorders, is actively recruiting participants, sponsored by Medical University of South Carolina.

RECRUITING
Registry status
NA
Development phase
80 participants
Enrollment target
1
Study location

Study Summary

This is a study to find out if a device that temporarily alters brain activity (repetitive transcranial magnetic stimulation, rTMS) might be used to change how people with anxiety or related concerns cope with feared or anxiety-producing situations. The study is recruiting people who recently started treatment for anxiety or a related concern. The study involves 3 visits to the Medical University of South Carolina. At the first visit, participants do interviews and surveys asking about anxiety and related concerns, and they also do tasks where they see and react to emotional pictures while their brain activation is measured. At the next two visits, participants receive rTMS, which works by rapidly turning a focused magnetic field on and off repeatedly over the head in a way that passes directly through the hair, scalp, and skull and onto the brain and can temporarily increase brain activity under the magnetic field. After rTMS, participants do two tasks where they see and react to emotional situations while wearing sensors on their hand, arms, face, and head. Each visit in this study is expected to last between 2 - 4 hours. This is not a treatment study, but the study is being conducted with the hope that it will help improve treatment in the future.

Primary Outcome

Fear-potentiated startle is measured during an experimental task in which participants prepare to avoid, escape, or simply be exposed to aversive pictures. Fear-potentiated startle measures motivational activation during the preparation period.

Conditions Studied

Interventions

  • DEVICE Repetitive Transcranial Magnetic Stimulation (rTMS)

Study Locations (1)

South Carolina

  • Medical University of South Carolina - Charleston

Trial Details

FieldValue
Enrollment Target 80 participants
Start Date 2021-06-26
Est. Completion 2026-12-30
Phase NA

What NCT04824105 shows while recruiting

NCT04824105 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 1,139-participant average among 84 other Anxiety Disorders trials with a reported enrollment target (93% lower).

The record links to 1 condition, with Anxiety Disorders appearing as the primary indexed condition, and to 1 intervention - of which Repetitive Transcranial Magnetic Stimulation (rTMS) is the first listed.

NCT04824105 reports a single indexed study location in South Carolina.

Frequently Asked Questions

What is clinical trial NCT04824105 about?

NCT04824105 is a clinical study titled "Modulating Anxious Coping". This is a study to find out if a device that temporarily alters brain activity (repetitive transcranial magnetic stimulation, rTMS) might be used to change how people with anxiety or related concerns cope with feared or anxiety-producing situations. The study is recruiting people who recently starte...

What is the current status of trial NCT04824105?

This trial is currently recruiting. It is a NA study. The enrollment target is 80 participants. The study started on 2021-06-26. Estimated completion is 2026-12-30.

What conditions does trial NCT04824105 study?

This clinical trial studies the following conditions: Anxiety Disorders.

What interventions are being tested in trial NCT04824105?

The interventions under investigation include: Repetitive Transcranial Magnetic Stimulation (rTMS) (DEVICE).

Who is sponsoring clinical trial NCT04824105?

This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04824105 being conducted?

This trial has 1 study location across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Anxiety Disorders

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04824105's enrollment target sits among peer trials

80 55th of 84 higher than 29 of 84 other Anxiety Disorders trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Anxiety Disorders trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04824105, the US trial registry maintained by the National Library of Medicine. NCT04824105 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.