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Anxiety Disorders clinical trials
42 of 85 indexed Anxiety Disorders trials are currently recruiting.
85 US clinical trials · 42 currently recruiting
Anxiety Disorders is the subject of 85 registered US clinical trials on ClinicalTrials.gov, 42 of them currently open to new participants. 10 are in Phase 3-4 (later-stage) and 11 in Phase 1-2 (earlier-stage). The most active sponsor is Massachusetts General Hospital, running 5 of these trials.
The research picture
Anxiety Disorders has 85 registered US clinical trials, 42 of them open to new participants right now, about 49% of the total.
- 42
- recruiting participants now
- 49%
- of trials open to enrollment
- 10
- in Phase 3–4 (later-stage)
- 5
- top sponsor: Massachusetts General Hospital
Active & Recent Trials
85 total, page 2 of 2
Testing a Transdiagnostic TMS Treatment Target
Brigham and Women's Hospital
NCT06282146
Harnessing Mobile Technology to Reduce Mental Health Disorders in College Populations
Washington University School of Medicine
NCT04162847
Transdiagnostic Behavioral Activation Therapy for Youth Anxiety and Depression
Rutgers University
NCT01829100
AZD7325 Proof of Concept in Patients With Generalized Anxiety Disorder (GAD)
AstraZeneca
NCT00808249
Safety and Efficacy Maintenance Study of Quetiapine SR to Treat GAD Patients.
AstraZeneca
NCT00314210
A Comparison of Duloxetine Hydrochloride, Marketed Comparator, and Placebo in the Treatment of Generalized Anxiety Disorder
Eli Lilly and Company
NCT00122850
Telephone-Based Care Management Program for Individuals With Anxiety Disorders
University of Pittsburgh
NCT00158327
Efficacy Evaluation of a Unified Transdiagnostic Treatment for Anxiety Disorders
Boston University Charles River Campus
NCT01243606
A Cognitive-Behavioral Intervention for Depression and Anxiety in COPD
US Department of Veterans Affairs
NCT00105911
School-based Treatment of Anxiety Research Study (STARS)
UConn Health
NCT01761396
Treatment for Specific Phobias in Children
Virginia Polytechnic Institute and State University
NCT00051220
Flourishing and Virtue in Cognitive-Behavioral Therapy for Anxiety and Depressive Disorders
Boston University Charles River Campus
NCT05120232
Explanatory Clinical Trial of a Novel Parent Intervention for Childhood Anxiety (SPACE)
Yale University
NCT02310152
Quetiapine Extended Release (XR) in Bipolar Patients With Comorbid Generalized Anxiety Disorder (GAD)
University Hospitals Cleveland Medical Center
NCT00671853
Retraining Attention to Treat Alcohol Dependence and Social Anxiety
University of Cincinnati
NCT01886716
Family-Focused CBT Skills App and Standard Self Help Options for Childhood Anxiety
Kansas City Center for Anxiety Treatment, P.A.
NCT03269370
Inhaled Oxytocin and HPA Axis Reactivity
University of North Carolina, Chapel Hill
NCT03593473
Mindfulness-based Stress Reduction and Cognitive Function in Stress and Aging
Washington University School of Medicine
NCT01693874
Personalized Feedback for Smokers With Elevated Anxiety Sensitivity
University of Houston
NCT03382093
Feasibility of Collateral Information Review and Its Impact on Clinical Decision-Making
Mclean Hospital
NCT04635748
Reward Processes and Rehearsal in Exposure Therapy
University of California, Los Angeles
NCT06132425
Integrated CBT for Cannabis Dependence With Co-occurring Anxiety Disorders
Louisiana State University and A&M College
NCT01875796
Transdiagnostic Sleep and Anxiety Treatment
Florida State University
NCT03664310
A Single-Session Intervention for Families on Waitlists for Child Anxiety Treatment
Florida International University
NCT05841680
Anxiety in Older Veterans
VA Office of Research and Development
NCT02400723
Threat Interpretation Bias as Cognitive Marker and Treatment Target in Pediatric Anxiety
University of Denver
NCT04245501
Effect of Mindfulness Meditation on Physiological Response to Unpredictable Stimuli
Georgetown University
NCT03206437
Evaluating a Personalized Trans-Diagnostic Group Therapy for Anxiety
Stanford University
NCT03457922
Benzodiazepine Taper With Cognitive Behavioral Therapy in Patients Using Prescription Opioids
University of California, Los Angeles
NCT05573906
Relaxation Treatment for Anxiety in Adults Aged 60 or Older
Palo Alto Veterans Institute for Research
NCT02429778
School-based Treatment for Anxious Children
Johns Hopkins University
NCT00536094
Study of Treatment for Opioid Dependence and Anxiety Disorders
Mclean Hospital
NCT02252068
Treatment Effects of Escitalopram (Lexapro®) on Generalized Anxiety Disorder in Patients With HIV and AIDS
Duke University
NCT00887679
Strategies for Treating Anxiety Research Study
University of Nevada, Las Vegas
NCT05398016
Antiglucocorticoid Therapy for Cognitive Impairment in Late-life Anxiety Disorders
Washington University School of Medicine
NCT01333098
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 5 |
| Phase 2 | 6 |
| Phase 3 | 8 |
| Phase 4 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Anxiety Disorders Trial Landscape
85 indexed Anxiety Disorders studies · 42 recruiting (49%).
Phase mix: 10 late (III/IV) vs 11 early (I/II).
Top sponsor: Massachusetts General Hospital (5 trials), 9 others listed. 35 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Anxiety Disorders?
PlainTrial tracks 85 US clinical trials for Anxiety Disorders, of which 42 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Anxiety Disorders?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.