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ClinicalTrials.gov 42 recruiting now full pipeline

Anxiety Disorders: full-pipeline trial registry

42 of 85 indexed Anxiety Disorders trials are currently recruiting.

Corpus placement: #165 of 28,707 conditions by registered trial count.

85 US clinical trials · 42 currently recruiting · #165 of 28,707 conditions by registered trial count

Anxiety Disorders: 85 US clinical trials tracked, 42 recruiting.

Anxiety Disorders is the subject of 85 registered US clinical trials on ClinicalTrials.gov, 42 of them currently open to new participants. 10 are in Phase 3-4 (later-stage) and 11 in Phase 1-2 (earlier-stage). The most active sponsor is Massachusetts General Hospital, running 5 of these trials.

Enrollment posture brief

Registry condition anxiety-disorders

OPEN 42 | RECR 49% | LATE 10 | EARLY 11 | RANK #165 | SPON 5

Nearest open-share peer: Metastatic Malignant Solid Neoplasm (49% recruiting · 93 trials)

Pancreatic Ductal Adenocarci65.9%Suicidal Ideation61.2%Anatomic Stage III Breast Ca56.5%Anxiety Disorders (this)49%Cataract23.5%
Open-enrollment share among volume-matched conditions near Anxiety Disorders

Anxiety Disorders lists 42 open slots (49% of 85 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Anxiety Disorders on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Anxiety Disorders is recruiting above its size-band peers.

    42 of 85 indexed trials (49.4%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Anxiety Disorders trials is spread across many organizations.

    Massachusetts General Hospital accounts for 5 of 85 trials (5.9%). 57 distinct sponsors appear on at least one study for this condition label.

  3. Typical Anxiety Disorders enrolment sits around 109 participants.

    Median target enrolment is 109 among the 85 trials that report a genuine target (sentinel values excluded). 39 of those (45.9%) plan for fewer than 100 participants.

  4. Anxiety Disorders research is mostly interventional.

    75 interventional and 10 observational studies make up this index (88.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 15Phase 26Phase 38Phase 42

Open and recent trials

85 total, page 2 of 2

ACTIVE NOT RECRUITING Early Phase 1 10 participants

Testing a Transdiagnostic TMS Treatment Target

Brigham and Women's Hospital

NCT06282146

COMPLETED NA 6,205 participants

Harnessing Mobile Technology to Reduce Mental Health Disorders in College Populations

Washington University School of Medicine

NCT04162847

COMPLETED NA 895 participants

Transdiagnostic Behavioral Activation Therapy for Youth Anxiety and Depression

Rutgers University

NCT01829100

COMPLETED Phase 2 725 participants

AZD7325 Proof of Concept in Patients With Generalized Anxiety Disorder (GAD)

AstraZeneca

NCT00808249

COMPLETED Phase 3 575 participants

Safety and Efficacy Maintenance Study of Quetiapine SR to Treat GAD Patients.

AstraZeneca

NCT00314210

COMPLETED Phase 3 480 participants

A Comparison of Duloxetine Hydrochloride, Marketed Comparator, and Placebo in the Treatment of Generalized Anxiety Disorder

Eli Lilly and Company

NCT00122850

COMPLETED Phase 3 360 participants

Telephone-Based Care Management Program for Individuals With Anxiety Disorders

University of Pittsburgh

NCT00158327

COMPLETED NA 250 participants

Efficacy Evaluation of a Unified Transdiagnostic Treatment for Anxiety Disorders

Boston University Charles River Campus

NCT01243606

COMPLETED NA 222 participants

A Cognitive-Behavioral Intervention for Depression and Anxiety in COPD

US Department of Veterans Affairs

NCT00105911

COMPLETED NA 216 participants

School-based Treatment of Anxiety Research Study (STARS)

UConn Health

NCT01761396

COMPLETED Phase 1 150 participants

Treatment for Specific Phobias in Children

Virginia Polytechnic Institute and State University

NCT00051220

COMPLETED NA 125 participants

Flourishing and Virtue in Cognitive-Behavioral Therapy for Anxiety and Depressive Disorders

Boston University Charles River Campus

NCT05120232

COMPLETED NA 124 participants

Explanatory Clinical Trial of a Novel Parent Intervention for Childhood Anxiety (SPACE)

Yale University

NCT02310152

COMPLETED Phase 3 120 participants

Quetiapine Extended Release (XR) in Bipolar Patients With Comorbid Generalized Anxiety Disorder (GAD)

University Hospitals Cleveland Medical Center

NCT00671853

COMPLETED NA 115 participants

Retraining Attention to Treat Alcohol Dependence and Social Anxiety

University of Cincinnati

NCT01886716

COMPLETED NA 110 participants

Family-Focused CBT Skills App and Standard Self Help Options for Childhood Anxiety

Kansas City Center for Anxiety Treatment, P.A.

NCT03269370

COMPLETED Phase 2 109 participants

Inhaled Oxytocin and HPA Axis Reactivity

University of North Carolina, Chapel Hill

NCT03593473

COMPLETED Phase 1 103 participants

Mindfulness-based Stress Reduction and Cognitive Function in Stress and Aging

Washington University School of Medicine

NCT01693874

COMPLETED NA 95 participants

Personalized Feedback for Smokers With Elevated Anxiety Sensitivity

University of Houston

NCT03382093

COMPLETED 89 participants

Feasibility of Collateral Information Review and Its Impact on Clinical Decision-Making

Mclean Hospital

NCT04635748

COMPLETED NA 88 participants

Reward Processes and Rehearsal in Exposure Therapy

University of California, Los Angeles

NCT06132425

COMPLETED Phase 1 68 participants

Integrated CBT for Cannabis Dependence With Co-occurring Anxiety Disorders

Louisiana State University and A&M College

NCT01875796

COMPLETED NA 61 participants

Transdiagnostic Sleep and Anxiety Treatment

Florida State University

NCT03664310

COMPLETED NA 59 participants

A Single-Session Intervention for Families on Waitlists for Child Anxiety Treatment

Florida International University

NCT05841680

COMPLETED NA 56 participants

Anxiety in Older Veterans

VA Office of Research and Development

NCT02400723

COMPLETED NA 50 participants

Threat Interpretation Bias as Cognitive Marker and Treatment Target in Pediatric Anxiety

University of Denver

NCT04245501

COMPLETED NA 45 participants

Effect of Mindfulness Meditation on Physiological Response to Unpredictable Stimuli

Georgetown University

NCT03206437

COMPLETED 45 participants

Evaluating a Personalized Trans-Diagnostic Group Therapy for Anxiety

Stanford University

NCT03457922

COMPLETED NA 42 participants

Benzodiazepine Taper With Cognitive Behavioral Therapy in Patients Using Prescription Opioids

University of California, Los Angeles

NCT05573906

COMPLETED NA 40 participants

Relaxation Treatment for Anxiety in Adults Aged 60 or Older

Palo Alto Veterans Institute for Research

NCT02429778

COMPLETED Phase 3 40 participants

School-based Treatment for Anxious Children

Johns Hopkins University

NCT00536094

COMPLETED NA 37 participants

Study of Treatment for Opioid Dependence and Anxiety Disorders

Mclean Hospital

NCT02252068

COMPLETED Phase 3 30 participants

Treatment Effects of Escitalopram (Lexapro®) on Generalized Anxiety Disorder in Patients With HIV and AIDS

Duke University

NCT00887679

COMPLETED NA 27 participants

Strategies for Treating Anxiety Research Study

University of Nevada, Las Vegas

NCT05398016

COMPLETED Phase 1 15 participants

Antiglucocorticoid Therapy for Cognitive Impairment in Late-life Anxiety Disorders

Washington University School of Medicine

NCT01333098

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Phase Distribution

PhaseTrial count
Phase 1 5
Phase 2 6
Phase 3 8
Phase 4 2

Named interventions

Most-linked intervention names on Anxiety Disorders records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Mindful Self-Compassion Behavioral
2 trials
Fluoxetine Drug
2 trials
Diaphragmatic Breathing Behavioral
2 trials
CBT Behavioral
2 trials
Progressive Muscle Relaxation Behavioral
2 trials
Cognitive Behavioral Therapy (CBT) Behavioral
2 trials
Repetitive Transcranial Magnetic Stimulation (rTMS) Device
2 trials
Ketamine Drug
2 trials

US sites by state

Facility locations filed on Anxiety Disorders trials. A trial with sites in several states counts in each.

Massachusetts 15 trials
California 15 trials
Texas 8 trials
Maryland 8 trials
Florida 6 trials
Pennsylvania 5 trials
New York 5 trials
Connecticut 5 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Anxiety Disorders page

85 registered trials, 42 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Anxiety Disorders condition card totals 85 registered trials; most-linked intervention Mindful Self-Compassion; top US site state Massachusetts. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.