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NCT05228964 · ClinicalTrials.gov registry record · NA
Focused Ultrasound Amygdala Neuromodulation
A NA study of Depression and PTSD, sponsored by University of Texas at Austin.
- Active
- Registry status
- NA
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT05228964: Active NA study of Depression and PTSD, sponsored by University of Texas at Austin.
NCT05228964 is a NA study of Depression and PTSD that is active but no longer recruiting, run by University of Texas at Austin. The registered enrollment target is 20 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05228964, a NA study of Depression and PTSD, is active but no longer recruiting, sponsored by University of Texas at Austin.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of the study is to examine the feasibility and potential efficacy of low-intensity focused ultrasound as a method of modulating amygdala function to promote improvements in symptoms of an affective disorder. Ultrasound is frequently and safely utilized for diagnostic purposes. In this study, the investigators will utilize magnetic resonance imaging (MRI) and neuronavigation to target the left amygdala and apply ultrasound. This will be conducted once a day, 5 days a week, for 3 weeks. This will be an open-label, single-arm trial.
Primary Outcome
A measure of general distress related to mood and anxiety symptoms. Scores range from 10-50, with lower scores indicating less symptoms.
Conditions Studied
Interventions
- DEVICE Focused ultrasound
Study Locations (1)
Texas
- Health Discovery Building (HDB), 1601 Trinity St., Bldg B., Z0600 - Austin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2022-01-13 |
| Est. Completion | 2024-12-31 |
| Phase | NA |
What the registry record for NCT05228964 still lists
NCT05228964 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 786-participant average among 679 other Depression trials with a reported enrollment target (97% lower).
The record links to 4 conditions, with Depression appearing as the primary indexed condition, and to 1 intervention - of which Focused ultrasound is the first listed.
NCT05228964 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT05228964 about?
NCT05228964 is a clinical study titled "Focused Ultrasound Amygdala Neuromodulation". The purpose of the study is to examine the feasibility and potential efficacy of low-intensity focused ultrasound as a method of modulating amygdala function to promote improvements in symptoms of an affective disorder. Ultrasound is frequently and safely utilized for diagnostic purposes. In this st...
What is the current status of trial NCT05228964?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2022-01-13. Estimated completion is 2024-12-31.
What conditions does trial NCT05228964 study?
This clinical trial studies the following conditions: Depression, PTSD, Anxiety Disorders, Bipolar Depression.
What interventions are being tested in trial NCT05228964?
The interventions under investigation include: Focused ultrasound (DEVICE).
Who is sponsoring clinical trial NCT05228964?
This trial is sponsored by University of Texas at Austin, which has 257 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05228964 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Depression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05228964's enrollment target sits among peer trials
20 612th of 679 higher than 58 of 679 other Depression trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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