Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT02949934 · ClinicalTrials.gov registry record · Phase 2

Effects of Cortical Dopamine Regulation on Drinking, Craving, and Cognitive Control

A Phase 2 study of Alcohol Use Disorder, sponsored by Medical University of South Carolina.

Completed
Registry status
Phase 2
Development phase
90
Enrollment target
1
Study location

NCT02949934 is a Phase 2 study of Alcohol Use Disorder that has completed, run by Medical University of South Carolina. The registered enrollment target is 90 participants, below the 328-participant average among 184 other Alcohol Use Disorder trials with a reported enrollment target (73% lower). The trial reports 1 study location across 1 state.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT02949934, a Phase 2 study of Alcohol Use Disorder, has completed, sponsored by Medical University of South Carolina.

COMPLETED
Registry status
Phase 2
Development phase
90 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to determine whether the catechol-O-methyltransferase (COMT) inhibitor tolcapone, relative to placebo, reduces alcohol drinking and alcohol cue-elicited brain activation and increases brain activation associated with cognitive control as a function of a participant's genotype at a polymorphism in the COMT gene.

Conditions Studied

Alcohol Use Disorder

Interventions

  • DRUG Placebo
  • DRUG Tolcapone

Study Locations (1)

South Carolina

  • Medical University of South Carolina - Charleston

Trial Details

FieldValue
Enrollment Target 90 participants
Start Date 2016-05-01
Est. Completion 2021-04-13
Phase Phase 2

Sponsor

Medical University of South Carolina

755 total trials

Interested in This Trial?

Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT02949934

The ClinicalTrials.gov registry entry for NCT02949934 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 90 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 328-participant average among 184 other Alcohol Use Disorder trials with a reported enrollment target (73% lower). The listed sponsor is Medical University of South Carolina, which has 755 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Alcohol Use Disorder appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT02949934 reports 1 study location spanning 1 distinct geographic area - top geographies include South Carolina.

Frequently Asked Questions

What is clinical trial NCT02949934 about?

NCT02949934 is a clinical study titled "Effects of Cortical Dopamine Regulation on Drinking, Craving, and Cognitive Control". The purpose of this study is to determine whether the catechol-O-methyltransferase (COMT) inhibitor tolcapone, relative to placebo, reduces alcohol drinking and alcohol cue-elicited brain activation and increases brain activation associated with cognitive control as a function of a participant's gen...

What is the current status of trial NCT02949934?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 90 participants. The study started on 2016-05-01. Estimated completion is 2021-04-13.

What conditions does trial NCT02949934 study?

This clinical trial studies the following conditions: Alcohol Use Disorder.

What interventions are being tested in trial NCT02949934?

The interventions under investigation include: Placebo (DRUG), Tolcapone (DRUG).

Who is sponsoring clinical trial NCT02949934?

This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02949934 being conducted?

This trial has 1 study location across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Alcohol Use Disorder

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Explore more on PlainTrial

Alcohol Use Disorder

All registered trials for this condition

South Carolina

All trials with a study site in South Carolina

Recruiting now

Find trials open to new participants near you

Rankings

Top sponsors, conditions, and phases

Read our methodology - how this data is sourced, computed, and verified.

Related

Browse all → | Rankings →
Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.