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NCT03872128 · ClinicalTrials.gov registry record · Phase 1

The Role of Neuroactive Steroids in Stress, Alcohol Craving and Alcohol Use in Alcohol Use Disorders

A Phase 1 study of Alcohol Use Disorder, sponsored by Yale University.

Completed
Registry status
Phase 1
Development phase
91
Enrollment target
2
Study locations

NCT03872128 is a Phase 1 study of Alcohol Use Disorder that has completed, run by Yale University. The registered enrollment target is 91 participants, below the 328-participant average among 184 other Alcohol Use Disorder trials with a reported enrollment target (72% lower). The trial reports 2 study locations across 1 state.

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The verdict

NCT03872128, a Phase 1 study of Alcohol Use Disorder, has completed, sponsored by Yale University.

COMPLETED
Registry status
Phase 1
Development phase
91 participants
Enrollment target
2
Study locations

Study Summary

To use pregnenolone (PREG; 300; 500mg) daily versus placebo (PLA) as a probe to assess the role of neuroactive steroids in individuals with alcohol use disorder (AUD).

Conditions Studied

Alcohol Use Disorder

Interventions

  • DRUG Placebo
  • DRUG Pregnenolone300
  • DRUG Pregnenolone500

Study Locations (2)

Connecticut

  • The Yale Stress Center: Yale University - New Haven
  • Yale Stress Center - New Haven

Trial Details

FieldValue
Enrollment Target 91 participants
Start Date 2018-09-27
Est. Completion 2023-08-01
Phase Phase 1

Sponsor

Yale University

1,492 total trials

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What the Registry Record Tells You About NCT03872128

The ClinicalTrials.gov registry entry for NCT03872128 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 91 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 328-participant average among 184 other Alcohol Use Disorder trials with a reported enrollment target (72% lower). The listed sponsor is Yale University, which has 1,492 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Alcohol Use Disorder appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.

NCT03872128 reports 2 study locations spanning 1 distinct geographic area - top geographies include Connecticut.

Frequently Asked Questions

What is clinical trial NCT03872128 about?

NCT03872128 is a clinical study titled "The Role of Neuroactive Steroids in Stress, Alcohol Craving and Alcohol Use in Alcohol Use Disorders". To use pregnenolone (PREG; 300; 500mg) daily versus placebo (PLA) as a probe to assess the role of neuroactive steroids in individuals with alcohol use disorder (AUD).

What is the current status of trial NCT03872128?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 91 participants. The study started on 2018-09-27. Estimated completion is 2023-08-01.

What conditions does trial NCT03872128 study?

This clinical trial studies the following conditions: Alcohol Use Disorder.

What interventions are being tested in trial NCT03872128?

The interventions under investigation include: Placebo (DRUG), Pregnenolone300 (DRUG), Pregnenolone500 (DRUG).

Who is sponsoring clinical trial NCT03872128?

This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03872128 being conducted?

This trial has 2 study locations across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.